Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Amgen to present data on Nplate studies for chronic ITP at ASH Annual Meeting

Amgen today announced that it will present data from several key Nplate (romiplostim) studies at the 52nd Annual Meeting and Exposition of the American Society of Hematology (ASH), Dec. 4-7, 2010, in Orlando, Fla.

2 Dec 2010

HSS creates Center for Musculoskeletal Outcomes and Patient Oriented Research

Hospital for Special Surgery (HSS) announced the creation of the Center for Musculoskeletal Outcomes and Patient Oriented Research to translate information collected from an extensive patient population into studies that will guide experts in preventing, diagnosing and treating musculoskeletal disorders.

2 Dec 2010

Study reveals role of VSV in killing cancer cells through turning off major survival signal

Researchers from Boston University School of Medicine (BUSM) have identified a mechanism by which specific viruses acting as oncolytic agents can enter and kill cancer cells. This finding, which is currently featured in an online edition of the Journal of Virology, could help lead to the development of more targeted treatments against many types of cancer.

2 Dec 2010

Current Opinion in Lipidology journal publishes data on VB-201 for immune-mediated disorders

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced the publication of a new concept in the Current Opinion in Lipidology evaluating oxidized phospholipid analogs as potential treatments for chronic inflammatory diseases.

2 Dec 2010

Researchers show an oncolytic virus switches off cancer cell survival signal

1 Dec 2010

RCUK Academic Fellow to discuss microbial pathogens, immune system at Henry Wellcome Building

The Frank May Prize Lecture 2010 will be given by Dr Russell Wallis, speaking on microbial pathogens, and will be on Wednesday 1st December 2010, 5.30pm, in the Frank and Katherine May Lecture Theatre, Henry Wellcome Building (Lancaster Road), University of Leicester.

1 Dec 2010

Alliance of Specialty Medicine calls for permanent fix to Medicare SGR formula

In response to Congress acting to postpone unprecedented reimbursement cuts to doctors who treat Medicare patients, The Alliance of Specialty Medicine (Alliance) today called on lawmakers to work towards a permanent solution to fix to the program's Sustainable Growth Rate (SGR) formula so temporary fixes would no longer be necessary.

1 Dec 2010

Initial data from resminostat Phase II Hodgkin Lymphoma trial to be presented at 52nd ASH

4SC, a drug discovery and development company focused on autoimmune and cancer indications, today announced that initial safety and efficacy data from its ongoing Phase II Study with resminostat, a pan-Histone Deacetylase (HDAC) Inhibitor, in relapsed/refractory Hodgkin Lymphoma (HL) patients after high dose chemotherapy and autologous hematopoietic stem cell transplantation will be presented at the 52nd Annual Meeting of the American Society of Hematology (ASH) in Orlando, Florida, USA.

1 Dec 2010

NSAID Celebrex may help prevent non-melanoma skin cancer development: Research

New research shows the NSAID Celebrex may help prevent some non-melanoma skin cancers from developing in patients who have pre-cancerous actinic keratoses lesions and are at high risk for having the disease.

30 Nov 2010

Golimumab with methotrexate improves markers of inflammation and structural damage in RA patients

Magnetic resonance imaging (MRI) analyses from two Phase 3 clinical trials showed that once every four week subcutaneous injections of golimumab 50 mg plus methotrexate resulted in statistically significant improvements in markers of inflammation and structural damage in patients with active rheumatoid arthritis (RA) compared with placebo plus methotrexate.

30 Nov 2010

Cytheris' combinational therapy demonstrates possible therapeutic strategy for PML

Cytheris SA, a clinical-stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced the publication of a case study report based on successful treatment of Progressive Multifocal Leukoencephalopathy (PML) with combination therapy consisting of two investigational agents, Cytheris' recombinant human interleukin-7 (CYT107) and CMX001, an investigational, oral broad-spectrum antiviral drug (Chimerix, Research Triangle Park, NC) in the Journal of Antimicrobial Chemotherapy.

30 Nov 2010

Affymax, Takeda to regulate peginesatide drug for treating anemia in CRF patients

Affymax, Inc. and Takeda Pharmaceutical Company Limited , today announced that following pre-New Drug Application (NDA) discussions with the U.S. Food and Drug Administration (FDA), the companies will move forward with their regulatory strategy for the investigational drug, peginesatide, for the treatment of anemia in chronic renal failure (CRF) patients on dialysis in the United States.

29 Nov 2010

Study finds light exercise may protect against osteoarthritis

People at risk for osteoarthritis may be able to delay the onset of the disease or even prevent it with simple changes to their physical activity, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

29 Nov 2010

Superantigens can disrupt immune system, can cause more illnesses

Superantigens, the toxins produced by staphylococcus bacteria, are more complex than previously believed, reveals a team of researchers from the University of Gothenburg in an article published today in the scientific journal Nature Communications. Their discovery shows that the body's immune system can cause more illnesses than realised.

29 Nov 2010

Phase 3 trial: TYSABRI improves vision in MS patients

Results recently presented from a study of multiple sclerosis (MS) patients taking TYSABRI (natalizumab) are supported by a Canadian woman's improved vision since starting the therapy.

25 Nov 2010

Bacterial study confirms TLR2 signaling vital for activating human airway epithelial cells

Researchers from the Boston University School of Medicine (BUSM) have demonstrated that commensal species of the genus Neisseriae are low inducers of human airway epithelial cell responses as compared to the pathogenic species.

24 Nov 2010

African American cigarette smokers at higher risk of rheumatoid arthritis

A new study determined that African Americans who smoke cigarettes have a higher risk of developing rheumatoid arthritis (RA). RA risk is more pronounced among individuals positive for the HLA-DRB1 shared epitope, a genetic risk factor for RA. Findings from this study—the largest to date examining the impact of smoking on RA risk in an African American population—are available in the December issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

23 Nov 2010

Early diagnosis and treatment result in positive outcomes for RA patients

Positive outcomes in rheumatoid arthritis (RA) are closely linked to early diagnosis and treatment with disease-modifying antirheumatic drugs (DMARDs). A study by researchers in the Netherlands found that patients who are assessed by rheumatologists soon after RA symptoms appear are more likely to experience less joint destruction and improved chances of DMARD-free disease remission.

23 Nov 2010

Ergothioneine international congress 2011 to be held at UCLA

OXIS International, Inc., today announced that the "First International Congress on Ergothioneine, Anti-Oxidants, and Age Management Medicine" will be held Friday to Sunday, July 15-17, 2011, in the DeNeve Auditorium at the University of California, Los Angeles.

23 Nov 2010

Erbitux development program featured in ASCO's Clinical Cancer Advances report for third consecutive year

For the third year in a row, the American Society of Clinical Oncology (ASCO) has included Erbitux® (cetuximab) research in its annual report, Clinical Cancer Advances, which features the most significant studies of 2010. The report cites as a notable advance this year the finding that BRAF mutation status is a prognostic, not predictive, marker for Erbitux efficacy in metastatic colorectal cancer (mCRC).

23 Nov 2010

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Amgen to present data on Nplate studies for chronic ITP at ASH Annual Meeting

HSS creates Center for Musculoskeletal Outcomes and Patient Oriented Research

Study reveals role of VSV in killing cancer cells through turning off major survival signal

Current Opinion in Lipidology journal publishes data on VB-201 for immune-mediated disorders

Researchers show an oncolytic virus switches off cancer cell survival signal

RCUK Academic Fellow to discuss microbial pathogens, immune system at Henry Wellcome Building

Alliance of Specialty Medicine calls for permanent fix to Medicare SGR formula

Initial data from resminostat Phase II Hodgkin Lymphoma trial to be presented at 52nd ASH

NSAID Celebrex may help prevent non-melanoma skin cancer development: Research

Golimumab with methotrexate improves markers of inflammation and structural damage in RA patients

Cytheris' combinational therapy demonstrates possible therapeutic strategy for PML

Affymax, Takeda to regulate peginesatide drug for treating anemia in CRF patients

Study finds light exercise may protect against osteoarthritis

Superantigens can disrupt immune system, can cause more illnesses

Phase 3 trial: TYSABRI improves vision in MS patients

Bacterial study confirms TLR2 signaling vital for activating human airway epithelial cells

African American cigarette smokers at higher risk of rheumatoid arthritis

Early diagnosis and treatment result in positive outcomes for RA patients

Ergothioneine international congress 2011 to be held at UCLA

Erbitux development program featured in ASCO's Clinical Cancer Advances report for third consecutive year

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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