Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Rottapharm Madaus, Selvita sign drug discovery services contract

Rottapharm Madaus and Selvita announced today signature of a services contract for delivery of drug discovery services. The aim of this project is to deliver to Rottapharm Madaus a set of designed and synthesized compounds, including their optimized synthesis route, which will have a therapeutic potential in an indicated area.

20 Jul 2010

Rice University bioengineers win $1.7M NIH grant for cartilage-regeneration research

Bioengineers from Rice University's BioScience Research Collaborative have won a $1.7 million grant from the National Institutes of Health to develop an injectable mix of polymers and adult stem cells that can spur the growth of new cartilage in injured knees and other joints.

20 Jul 2010

Ronald Reagan UCLA Medical Center ranks first: U.S. News & World Report survey

Ronald Reagan UCLA Medical Center ranks as one of the top five American hospitals -- and the best hospital in the western United States for the 21st consecutive year -- according to a U.S. News & World Report survey that reviewed patient-outcomes data, reputation among physicians and other care-

17 Jul 2010

Amgen granted FDA priority review designation for denosumab BLA

Amgen today announced that the U.S. Food and Drug Administration (FDA) has granted priority review designation to denosumab, a subcutaneous RANK Ligand inhibitor, for the treatment of bone metastases to reduce skeletal related events (SREs) in patients with cancer.

17 Jul 2010

Johns Hopkins Hospital takes top spot in annual rankings of American hospitals for 20th year in a row

Once more — and for the 20th year in a row — The Johns Hopkins Hospital has taken the top spot in U.S. News & World Report's annual rankings of American hospitals, placing first in five medical specialties and in the top five in 10 others.

16 Jul 2010

Study shows high rate of return to pre-injury level of function with arthroscopic treatment

Athletes who undergo arthroscopic surgery for a mechanical disorder of the hip have a good chance of being able to return to their sport at a high level of competition, according to a study that will be presented at the annual meeting of the American Orthopaedic Society for Sports Medicine, held July 15-18 in Providence, R.I. Almost 80 percent of patients were able to return to play after hip arthroscopy at an average of 9.4 months after surgery, and roughly 90 percent were able to return to the same level of competition.

16 Jul 2010

AAOS releases evidence-based clinical practice guideline for treating glenohumeral joint osteoarthritis

The American Academy of Orthopaedic Surgeons has approved and released an evidence-based clinical practice guideline on "The Treatment of Glenohumeral Joint Osteoarthritis." This major joint in the shoulder - the ball and socket joint - is sometimes affected by osteoarthritis, causing pain, loss of function, and reduced quality of life.

16 Jul 2010

VCU Medical Center ranked in 2010-2011 Best Hospitals

The Virginia Commonwealth University Medical Center on Thursday was ranked in the 2010-2011 Best Hospitals in the country by U.S. News and World Report, making it one of 152 medical centers nationwide selected out of nearly 2,000 eligible institutions.

16 Jul 2010

The Children's Hospital, UCH to jointly establish new center for advanced maternal fetal medicine

The Children's Hospital and the University of Colorado Hospital have finalized an agreement to jointly establish a center for advanced maternal fetal medicine offering state-of-the-art care for high-risk pregnant women and their babies. The two leading academic medical centers have individually provided such services for more than three decades, and by building on already existing adult and pediatric expertise, they together will be able to provide unparalleled care and treatment for the region's most at-risk moms and babies.

16 Jul 2010

New findings on macrophage activation can facilitate development of early diagnosis tools

Immune system cells called macrophages spring into action to surround and destroy threats such as viruses or cancer cells. But sometimes the would-be protective response leads to persistent inflammation, which, in turn, can cause disease.Scientists don't know exactly how macrophages cross the line from being good cops to bad cops, but researchers at the University of Florida recently unearthed several clues about the mechanisms involved. Through the lens of two inflammation-related diseases, HIV and rheumatoid arthritis, they identified changes in specific proteins linked to the action of macrophages, white blood cells that are key to the body's natural defenses.

16 Jul 2010

ACTOS offers safety profile regarding risk of CV events in people with type 2 diabetes: Takeda

The U.S. Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee held a joint meeting primarily focused on reviewing the cardiovascular safety of rosiglitazone, as presented by the FDA and GlaxoSmithKline. Following this two day discussion, Takeda Pharmaceuticals North America, Inc. ("Takeda") underscores its position that ACTOS (pioglitazone HCl) offers an established safety profile regarding the risk of CV events in people living with type 2 diabetes.

16 Jul 2010

Ligand Pharmaceuticals announces launch of redesigned Web site

Ligand Pharmaceuticals Incorporated announces the launch of its completely redesigned Web site: www.ligand.com. The new Web site is designed as a comprehensive resource for investors, prospective corporate partners and the life science community to learn more about Ligand's business model, robust pipeline, high-profile partnerships and innovative technology.

15 Jul 2010

NIH awards MacroGenics $9.8 million grant for three projects

MacroGenics, Inc, a privately held biotechnology company that develops immunotherapeutics to treat autoimmune disorders, cancer and infectious diseases, today announced that the National Institutes of Health (NIH) has awarded the company three new grants representing total funding of $9.8 million.

15 Jul 2010

Plexxikon announces promising preclinical data of PLX3397

Plexxikon Inc. today announced promising preclinical data from in vivo Alzheimer's Disease studies demonstrating a dramatic reduction in activated microglia in the brains of very old (22 months) 3xTG-AD mice, a triple transgenic model for Alzheimer's Disease. This reduction of activated microglia led to significantly improved learning in the treated group.

15 Jul 2010

Hospital for Special Surgery named top hospital for orthopedics

Hospital for Special Surgery has been named the top hospital in the nation for orthopedics by U.S. News & World Report in its 2010 "America's Best Hospitals" issue. Once again the hospital ranked as a leader in rheumatology at number 3 in the nation. In addition, neurology was ranked at number 16.

15 Jul 2010

Mylan subsidiary receives FDA final approval for Nabumetone Tablets ANDA

Mylan Inc. today announced that its subsidiary Matrix Laboratories Limited has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Nabumetone Tablets USP, 500 mg and 750 mg.

15 Jul 2010

U-M Hospitals and Health Centers ranked 14th among America's best hospitals

The University of Michigan Hospitals and Health Centers have been ranked among the country's best hospitals, placing 14th overall for the second consecutive year by U.S. News & World Report magazine. This year, U-M was ranked in every specialty and those rankings went up in 11 of the 16 specialties.

15 Jul 2010

Susceptibility to Behcet's disease associated with genes involved in body's immune response

Researchers with the National Institutes of Health have found susceptibility to Behcet's disease, a painful, inflammatory condition, to be associated with genes involved in the body's immune response.

14 Jul 2010

TLR7, TLR9 proteins could be culprit behind lupus patients' resistance to steroid treatments: Scientists

Two immune system proteins could be the culprit behind many lupus patients' resistance to widely used steroid treatments, scientists with the Baylor Research Institute in Dallas announced today. It is estimated that more than 5 million people suffer from lupus worldwide.

13 Jul 2010

Biogen Idec, Swedish Orphan Biovitrum present results from rFIXFc Phase 1/2a study in hemophilia B

Biogen Idec and Swedish Orphan Biovitrum AB today announced results from a Phase 1/2a open-label, dose-escalation, safety and pharmacokinetic study of the companies' long-lasting, fully-recombinant factor IX Fc fusion protein (rFIXFc) in hemophilia B patients. The data, which were presented at the World Federation of Hemophilia Congress in Buenos Aires, Argentina, on July 11, 2010, showed that rFIXFc was well tolerated and demonstrated an approximately three-fold increase in half-life compared to historical data for existing therapies.

12 Jul 2010

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Rottapharm Madaus, Selvita sign drug discovery services contract

Rice University bioengineers win $1.7M NIH grant for cartilage-regeneration research

Ronald Reagan UCLA Medical Center ranks first: U.S. News & World Report survey

Amgen granted FDA priority review designation for denosumab BLA

Johns Hopkins Hospital takes top spot in annual rankings of American hospitals for 20th year in a row

Study shows high rate of return to pre-injury level of function with arthroscopic treatment

AAOS releases evidence-based clinical practice guideline for treating glenohumeral joint osteoarthritis

VCU Medical Center ranked in 2010-2011 Best Hospitals

The Children's Hospital, UCH to jointly establish new center for advanced maternal fetal medicine

New findings on macrophage activation can facilitate development of early diagnosis tools

ACTOS offers safety profile regarding risk of CV events in people with type 2 diabetes: Takeda

Ligand Pharmaceuticals announces launch of redesigned Web site

NIH awards MacroGenics $9.8 million grant for three projects

Plexxikon announces promising preclinical data of PLX3397

Hospital for Special Surgery named top hospital for orthopedics

Mylan subsidiary receives FDA final approval for Nabumetone Tablets ANDA

U-M Hospitals and Health Centers ranked 14th among America's best hospitals

Susceptibility to Behcet's disease associated with genes involved in body's immune response

TLR7, TLR9 proteins could be culprit behind lupus patients' resistance to steroid treatments: Scientists

Biogen Idec, Swedish Orphan Biovitrum present results from rFIXFc Phase 1/2a study in hemophilia B

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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