Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Discovery of 100 new antiangiogenesis peptides

Using computer models and live cell experiments, biomedical engineers at the Johns Hopkins University School of Medicine have discovered more than 100 human protein fragments that can slow or stop the growth of cells that make up new blood vessels.

5 Oct 2008

Statin-induced muscle disorders are focus of $2.5 million in grants from NIH

Approximately 200,000 of the 38 million people in the U.S. who take statins to treat high cholesterol may develop life-threatening muscle disease.

2 Oct 2008

New gout gene discovery

Researchers have identified two new genes - and confirmed the role of a third gene - associated with increased risk of higher levels of uric acid in the blood, which can lead to gout, a common, painful form of arthritis.

30 Sep 2008

Arthritis treatments glucosamine and chondroitin shown to be no better than placebo

According to the latest research, the popular supplements glucosamine and chondroitin sulfate, used to fight arthritis and joint pain, do not seem to work any better than a placebo in slowing the loss of knee cartilage in osteoarthritis.

30 Sep 2008

An occupational therapist-led approach gets people with osteoarthritis moving

Physical activity is the cornerstone of any healthy lifestyle - and especially for people with osteoarthritis as exercise helps maintain good joint health, manage their symptoms, and prevent functional decline. Osteoarthritis, however, often makes physical activity, such as exercise, and even performing daily activities, a challenge.

29 Sep 2008

Arana files U.S. IND for lead anti-Inflammatory

Biotechnology company Arana Therapeutics Limited today announced it has submitted an Investigational New Drug application (IND) to the FDA (U.S. Food and Drug Administration) for the anti-inflammatory product ART621 in a rheumatoid arthritis (RA) indication.

29 Sep 2008

Pain is not a symptom of arthritis, pain causes arthritis

Pain is more than a symptom of osteoarthritis, it is an inherent and damaging part of the disease itself, according to a study published today in journal Arthritis and Rheumatism.

29 Sep 2008

Arana updates inflammatory pipeline milestones

Biotechnology company Arana Therapeutics Limited today provided an update on the major inflammatory compounds in its drug development pipeline. As part of this update, Arana said it has developed a new antibody candidate ART123, targeting inflammatory diseases and it plans to start a Phase I clinical trial for age-related macular degeneration (AMD) candidate PMX53 in 2009.

21 Sep 2008

Gender differences in experience of rheumatism

Rheumatoid arthritis is often a more painful experience for women than it is for men, even though the visible symptoms are the same.

15 Sep 2008

BioServe introduces customizable DNA panels for genetic research

BioServe has announced a more affordable pricing plan for its vast bank of DNA with comprehensive, de-identified, covariate data that includes age, gender, diet, body mass index (BMI), and race. In addition, each sample has data on the complete diagnostic and treatment history of the donor.

14 Sep 2008

GlaxoSmithKline and Cellzome announce major strategic alliance

Cellzome Inc. and GlaxoSmithKline have announced the signing of a worldwide strategic alliance to discover, develop and market novel kinase-targeted therapeutics to treat inflammatory diseases.

10 Sep 2008

Asian-Americans, blacks more skeptical of joint replacement surgery than whites, study finds

Blacks and Asian-Americans perceive joint replacement surgery as a riskier procedure than whites do, according to a study published in the August issue of the Journal of Rheumatology, Reuters Health reports.

9 Sep 2008

FDA forces manufacturers of TNF-blockers to highlight risk of fungal infections

The U.S. Food and Drug Administration today announced that the manufacturers of Humira, Cimzia, Enbrel, and Remicade must strengthen the existing warnings, in the Warnings and Precaution sections of the drugs' prescribing information and Medication Guides, on the risk of developing opportunistic fungal infections. Some patients with invasive fungal infections have died.

5 Sep 2008

Hurricane Katrina increased mental and physical health problems in New Orleans by up to three times

Half the residents of New Orleans were suffering from poor mental and physical health more than a year after their homes and community were devastated by Hurricane Katrina in August 2005, according to research published in the September issue of the UK-based Journal of Clinical Nursing.

3 Sep 2008

Knee osteoarthritis a growing problem in U.S.

Almost half of all U.S. adults and nearly two-thirds of obese adults will develop painful osteoarthritis of the knee by age 85, a study based at the University of North Carolina at Chapel Hill suggests.

2 Sep 2008

Researchers find genetic proof on how osteoarthritis destroys cartilage

A team of orthopaedic researchers has found definitive, genetic proof of how the most common form of arthritis destroys joint cartilage in nearly 21 million aging Americans, according to a study published online Sept. 2 in the Journal of Bone and Mineral Research. The findings serve as an important foundation for the design of new treatments for osteoarthritis (OA), researchers said.

2 Sep 2008