Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Medarex announces preliminary data for investigational anti-PD-1 antibody

Medarex, Inc. has announced preliminary data from an ongoing Phase 1 study of MDX-1106 (ONO-4538: development code of Ono Pharmaceutical Co., Ltd.), a fully human anti-PD-1 antibody.

2 Jun 2008

Global drug research programme comes to Diamond in Oxfordshire

Diamond has announced that USA-based global biotechnology company Vertex Pharmaceuticals Incorporated is the first industrial user at the UK's world class new research facility, Diamond Light Source

27 May 2008

Iraq war and risk of developing bronchiolitis

A large group of soldiers returning from Iraq have been diagnosed with bronchiolitis, a disease affecting the small airways of the lung, according to Vanderbilt University Medical Center physicians who will present their findings at the American Thoracic Society's 2008 International Conference in Toronto on Wednesday, May 21.

21 May 2008

Tuberculosis not the only risk from new immunological drugs

A new survey cautions physicians that drugs commonly prescribed for patients suffering from immunological disorders such as rheumatoid arthritis and inflammatory bowel disease may carry risks of serious infections other than the known risk of tuberculosis. The survey published is in the June 1 issue of Clinical Infectious Diseases, currently available online.

20 May 2008

VCU research team awarded NIH grant to study asthma, allergic disease

A team of Virginia Commonwealth University researchers has received a National Institute of Allergy and Infectious Diseases grant totaling nearly $7.3 million for a Cooperative Research Center to study various aspects of asthma and allergic disease.

20 May 2008

Minocycline may find new life as a stroke treatment

An old intravenous antibiotic may have new life as a stroke treatment, researchers say. Minocycline appears to reduce stroke damage in multiple ways - inhibiting white blood cells and enzymes that, at least acutely, can destroy brain tissue and blood vessels, respectively, says Dr. David Hess, chair of the Department of Neurology in the Medical College of Georgia School of Medicine.

19 May 2008

Researchers who helped millions with arthritis receive Janssen Award

Two British researchers who pioneered treatments which have helped millions of people with rheumatoid arthritis and other autoimmune diseases have been awarded the prestigious 2008 Dr. Paul Janssen Award for Biomedical Research, announced today.

13 May 2008

Breastfeeding may protect women from rheumatoid arthritis

Swedish researchers have found in a study on rheumatoid arthritis that breastfeeding protects women from the disease.

13 May 2008

Study shows how T cell's machinery dials down autoimmunity

A St. Jude Children's Research Hospital study shows that T cells, the body's master immune regulators, do not use simple on/off switches to govern the cellular machinery that regulates their development and function. Rather, they possess sophisticated molecular controls that enable them to adjust their function with exquisite precision. Such subtle adjustment enables T cells to modulate their development and function, including avoiding autoimmunity

12 May 2008

Molecular pathway in muscle helps explain effectiveness of diabetes interventions

Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), demonstrate for the first time in a mouse model that skeletal muscle cells cultured in a low-calorie environment refrain from differentiating, an energy-demanding process by which cells mature and specialize.

12 May 2008

New theory suggests how hepatitis C may cause rare immune disease

Of the hepatitis alphabet, the C variant may be the nastiest. In 1990, researchers observed that most patients with hepatitis C also develop a rare autoimmune disease called mixed cryoglobulinemia, a condition that frequently leads to cancer, arthritis or both.

10 May 2008

Study affirms effectiveness of medication for juvenile rheumatoid arthritis

Juvenile rheumatoid arthritis (JRA) is a chronic autoimmune disease that strikes children between the ages of newborn to 16 years. All children with JRA have joint pain, stiffness, and swelling and some also have fever and skin rashes.

9 May 2008

Outcomes of obese and nonobese patients undergoing revision total hip arthroplasty

Along with age and injuries, obesity is a leading risk factor for osteoarthritis (OA), a painful and disabling joint disease. While excessive weight can aggravate the toll on almost any joint, obesity has been associated with a higher prevalence of hip OA and an increase in total hip arthroplasty (THA).

8 May 2008

Study finds arthritis can be a barrier for adults seeking to manage diabetes through exercise

More than half of adults with diagnosed diabetes also have arthritis, a painful condition that can be a barrier to physical activity -- an important health strategy for managing diabetes, according to a study released by the Centers for Disease Control and Prevention in today's Morbidity and Mortality Weekly Report.

8 May 2008

A new search for causes of autism

Dr. Eric Fombonne, from the Research Institute of the MUHC at the Montreal Children's Hospital, is involved in a multi-site consortium to gather DNA samples from 2,000 autism patients and their families over the next three years.

7 May 2008

Relief in sight for arthritis triggered by viral infections such as Ross River fever

Australian scientists believe they may have discovered the possibility of relief for those suffering with the debilitating arthritis triggered by viral infections such as Ross River fever.

6 May 2008

New tool for tissue damage assessment

A tool with the potential to determine the level of tissue damage in patients with osteo-arthritis, sports injuries and other conditions affecting bone and cartilage is being developed by QUT researchers. Professor Oloyede said that the device, which he calls a "smarthroscope", may be able to reduce the cost of surgery, eliminate unnecessary surgery, and could be useful in developing countries.

2 May 2008

Breakthrough compound could lead to new class of antihypertensive drugs

University of Florida researchers have identified a drug compound that dramatically lowers blood pressure, improves heart function and - in a remarkable finding - prevents damage to the heart and kidneys in rats with persistent hypertension

1 May 2008

Aspirin a day cuts risk of common breast cancer

Scientists in the U.S. say an aspirin a day may afford women some protection against the most common type of breast cancer, estrogen receptor or ER-positive breast cancer.

30 Apr 2008

Mothers and offspring can share cells throughout life - with positive and negative effects

Cutting the umbilical cord doesn't necessarily sever the physical link between mother and child. Many cells pass back and forth between the mother and fetus during pregnancy and can be detected in the tissues and organs of both even decades later. This mixing of cells from two genetically distinct individuals is called microchimerism. The phenomenon is the focus of an increasing number of scientists who wonder what role these cells play in the body.

30 Apr 2008