Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Potential new targeted treatments for Lupus

New research provides clues about the causes of lupus symptoms and suggests specific new targeted treatment strategies, according to Nilamadham Mishra, M.D., from Wake Forest University Baptist Medical Center, in presentations this week at the American College of Rheumatology in Boston.

13 Nov 2007

Overexpression of neuroglobin reduces severity of Alzheimer's disease in mice

Mice genetically engineered to both overproduce the protein neuroglobin and to develop Alzheimer's disease (AD) had a much milder form of the disease when compared to mice engineered to have AD alone, researchers at the Buck Institute for Age Research have reported.

13 Nov 2007

Mycophenolate mofetil therapy effective for reducing lupus flares

Mayo Clinic researchers have shown that an immunosuppressive drug used in organ transplant cases is effective in reducing flare-ups in patients with systemic lupus erythematosus (SLE)

13 Nov 2007

Lexicon files investigational NDA for LX2931 in rheumatoid arthritis

Lexicon Pharmaceuticals, Inc. has announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration (FDA) for LX2931, an oral drug candidate for rheumatoid arthritis and other autoimmune conditions.

13 Nov 2007

Discovery of key pathway, potential drug targets in autoinflammatory disease

Molecular biologists at Jefferson's Kimmel Cancer Center in Philadelphia have detailed the cascade of cellular events behind some potentially dangerous autoinflammatory diseases.

13 Nov 2007

Human Genome Sciences announces positive phase 2 LymphoStat-B results

Human Genome Sciences, Inc. has announced the presentation of Phase 2 clinical results demonstrating that LymphoStat-B (belimumab) achieved a sustained improvement in disease activity across multiple clinical measures, decreased the frequency of disease flares over time, and was well tolerated through 2.5 years on treatment in combination with standard of care in patients with active systemic lupus erythematosus (SLE).

13 Nov 2007

Research sheds new light on how joints work

Mice that don't produce lubricin, a thin film of protein found in the cartilage of joints, showed early wear and higher friction in their joints, a new study led by Brown University researchers shows.

6 Nov 2007

Prazosin curbs brain damage from post-traumatic stress disorder

A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia.

6 Nov 2007

NSAIDs may lower risk of Parkinson's disease

Over-the-counter pain medications known as non-steroidal anti-inflammatory drugs (NSAIDs) may reduce a person's risk of Parkinson's disease, according to a study published in the November 6, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

6 Nov 2007

Scientists challenge the underlying scientific premise behind folic acid fortification

Scientists at the Institute of Food Research have highlighted possible consequences of fortifying flour with folic acid due to new evidence of how it is absorbed by the body.

5 Nov 2007

Researchers identify gene behind rheumatoid arthritis

University of Manchester researchers have identified a genetic variant in a region on chromosome 6 that is associated with rheumatoid arthritis (RA), the most common inflammatory arthritis affecting 387,000 people in the UK.

From The University of Manchester 5 Nov 2007

Fibromyalgia pain caused by neuron mismatch

The unexplained pain experienced by patients with fibromyalgia is the result of a mismatch between sensory and motor systems, new research suggests.

31 Oct 2007

Lithium commonly used to treat bi-polar disorder increases lifespan in Nematode worms

Nematode worms treated with lithium show a 46 percent increase in lifespan, raising the tantalizing question of whether humans taking the mood affecting drug are also taking an anti-aging medication.

31 Oct 2007

Most people living longer except rheumatoid arthritis sufferers

New research by the Mayo Clinic has found that while most people are living longer the same is not true for sufferers from rheumatoid arthritis.

30 Oct 2007

Comparison of mortality trends among rheumatoid arthritis subjects

An autoimmune inflammatory disease that takes a progressive toll on the heart, kidney and liver as well as the joints, rheumatoid arthritis (RA) is associated with a high risk of early death.

29 Oct 2007

Research finds novel mechanism for synovial inflammation in degenerative arthritis

The most common degenerative joint disease, osteoarthritis (OA) is marked by the breakdown of articular cartilage, which is the type of cartilage that lines the ends of most limb bones.

29 Oct 2007

Smoking linked to enduring risk of psoriasis

According to new research smokers have a higher risk of developing the skin condition psoriasis.

29 Oct 2007

Extensive review supports safety of silicone breast implants

An exhaustive review - the first in almost a decade, including the latest evidence on the health effects of silicone breast implants - finds no increase in the risk of cancers, connective tissue diseases, or other serious chronic diseases.

28 Oct 2007

New imaging technique ensures rapid profiling of autoantibodies in rheumatoid arthritis

Using a new imaging technique, a fast and accurate profile of autoantibodies present in the blood serum of rheumatic patients can be made.

25 Oct 2007

Amazon jungle plant compound blocks tissue destruction

Scientists at Case Western Reserve University's School of Medicine have published in the Journal of Inflammation a remarkable discovery with a natural product derived from the Amazon rainforest.

24 Oct 2007