Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Pfizer adds warning to Celebrex arthritis drug

Pharmaceutical giant Pfizer has adapted the label of its Celebrex arthritis drug and added a prominent warning of possible cardiovascular risks, such as increased risk of heart attacks.

3 Aug 2005

Omega-6 fatty acids promote the growth of prostate tumor cells in the laboratory

A study conducted at the San Francisco VA Medical Center (SFVAMC) has demonstrated that omega-6 fatty acids such as the fat found in corn oil promote the growth of prostate tumor cells in the laboratory.

2 Aug 2005

New understanding of cell movement may yield ways to brake cancer's spread

From birth until death, our cells migrate: nerve cells make their vital connections, embryonic cells move to the proper places to form organs, immune cells zero in to destroy pathogenic organisms, and cancer cells metastasize, spreading deadly disease through the body. Scientists studying these migrations didn't know how cells determined where to go. Until now.

1 Aug 2005

Knee pain more often part of a package of aches and pains

A new study suggests that knee pain experienced by older people is usually not an isolated problem, but is more often part of a constellation of chronic aches.

29 Jul 2005

First trial of pramipexole for the treatment of fibromyalgia

The mechanism of fibromyalgia, a chronic illness characterized by muscle pain, fatigue, and sleep disturbances, is unknown and medications used to treat it (such as antidepressants, antiepileptics, muscle relaxants, antiinflammatories, sedative hypnotics, pain relievers and nutriceuticals) have had limited success.

28 Jul 2005

Most people with knee pain also have pain elsewhere

Joint pain, especially in the knees, is a common complaint in older patients and can impact quality of life. A team of researchers recently set out to examine how often knee pain is accompanied by pain elsewhere in the body and whether the presence of multiple joint pain affects older patients' general health and psychological status.

28 Jul 2005

Specialized immune-system B cells play dual role in triggering both kinds of immunity - innate and acquired

A specialized subpopulation of the antibody-producing B cells of the immune system plays a "double-barreled" role in triggering both kinds of immunity - innate and acquired, Duke University Medical Center immunologists have discovered.

26 Jul 2005

Rush to offer new treatment for arterio-venous malformations

Rush University Medical Center will be the first in Chicago and among the first hospitals in the nation to offer a promising new treatment for arterio-venous malformations (AVMs) following its approval by the FDA on July 21.

26 Jul 2005

Direct relationship between inflammation and glucose levels

Scientists at Galileo Pharmaceuticals, Inc. have demonstrated a direct relationship between inflammation and glucose levels. Through its recently established metabolic disease program, Galileo confirmed in preclinical models that inhibiting lipoxygenases, known mediators of inflammatory response, significantly lowers blood glucose levels in animal models of diabetes.

26 Jul 2005

Biologic treatments to treat the physical symptoms of psoriasis

More than 4.5 million adults in the United States have been diagnosed with psoriasis and 21 percent of those have moderate to severe psoriasis. This chronic condition, characterized by thick, red, scaly plaques that itch and bleed, not only makes the activities of daily life difficult, but also can affect a person's emotional well being.

21 Jul 2005

Ibuprofen can increase bleeding during surgery

Researchers from the Case Western Reserve University School of Dental Medicine recommend the discontinuation of ibuprofen prior to surgery to correct gum disease because blood loss is two times greater for those using the medication than those not taking it.

19 Jul 2005

Startling discovery about the properties of human bone

The scientists describe their results - finding a sort of "glue" in human bone - in the cover story of the August issue of the international scientific journal, Nature Materials. The article was published on-line on July 17. It describes how healthy bone resists fracture and how unhealthy bone fractures at the molecular level.

18 Jul 2005

Curcumin has potent anticancer powers

Curcumin, a spice commonly used in curries and other south Asian cooking, blocks a key biological pathway needed for development of melanoma and other cancers, say researchers from the University of Texas M. D. Anderson Cancer Center.

12 Jul 2005

New understanding of degeneration of brain cells in patients with Alzheimer's, Huntington's, and Parkinson's diseases

A ground-breaking new research approach to understanding the cellular processes of Alzheimer's and other degenerative diseases has revealed a promising pathway to the development of new types of drugs for these diseases.

11 Jul 2005

Research explains one of the fundamental mysteries of multiple sclerosis

Scientists have pinpointed a chemical messenger that frees some white blood cells from the body's normal constraints, allowing the cells to act like renegades that could damage nerves in the central nervous system. The work, to be published in the July 15 issue of the Journal of Immunology and just published on-line, helps explain one of the fundamental mysteries of multiple sclerosis (MS).

11 Jul 2005

Scientists discover how an HIV protein fragment shuts down an immune response

The HIV virus hides out in the very immune system cells that are meant to protect the body from viral infection. But how does it prevent these cells from mounting a full-scale attack against the invader?

11 Jul 2005

Vioxx safe enough for Canadian market says health panel

A canadian health advisory panel says that Merck's arthritis drug Vioxx should be allowed to go on sale again in the country, 10 months after the company withdrew the blockbuster painkiller over reports that it increased the risk of heart disease.

11 Jul 2005

Stress on arthritic knees significantly eased by small weight loss

A new study says that overweight people suffering from arthritis in the knees, could diminish the stress the knees take with every step, by just losing one pound.

11 Jul 2005

Tetracycline antibiotic shows promise for treating osteoarthritis

A tetracycline antibiotic, doxycycline, has been successfully used to treat a wide-range of bacterial infections. In addition to its effects as an antibiotic, doxycycline has other actions as a drug and, in laboratory studies with animals and with human tissue, can inhibit the degradation of cartilage in a way that could be useful for the treatment of osteoarthritis (OA).

28 Jun 2005

Patients with rheumatoid arthritis are at increased risk of coronary artery disease

The findings of research published today in Arthritis Research & Therapy show that CAD is accelerated in RA patients, and patients with both RA and CAD are at an increased risk of death from heart disease.

28 Jun 2005