Arthritis News and Research

Latest Arthritis News and Research

Study throws light on why gout not well managed in many patients

A study published online this month in the Arthritis Care and Research journal is shedding light on why gout, a painful and common form of arthritis, is not well managed in many patients. The journal is published by the American College of Rheumatology.

22 Jan 2016

Bariatric surgery prior to knee replacement benefits morbidly obese patients with end-stage osteoarthritis

Previous research studies have linked obesity to adverse outcomes and increased costs following total knee replacement surgery (TKR). A new, computer model-based evaluation appearing in the Journal of Bone and Joint Surgery, supports bariatric surgery in morbidly obese patients with end-stage osteoarthritis (loss of cartilage and joint pain, caused by aging and use) prior to TKR.

22 Jan 2016

Immunotherapy could be the future of cancer treatments

For decades most cancers have been treated with the standard of care treatments which typically include surgery, radiation and/or chemotherapy. Now there is talk that immunotherapy represents "the future of cancer treatments."

21 Jan 2016

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Scientists at Sanford Burnham Prebys Medical Discovery Institute have solved the atomic structure of a unique ubiquitin ligase complex. Ubiquitin is best known for its role in protein degradation, but more recently seen as important for cell signaling, DNA repair, anti-inflammatory, and immune responses.

21 Jan 2016

Genetics play vital role in knee pain sensitivity

Genetics play a key role in knee pain sensitivity, according to a team of researchers studying knee osteoarthritis patients.

20 Jan 2016

BENEPALI granted marketing authorization in the EU for treatment of chronic inflammatory diseases

The joint venture between Biogen and Samsung BioLogics, Samsung Bioepis, has been granted European Commission (EC) approval for BENEPALI , an etanercept biosimilar referencing Enbrel.

19 Jan 2016

TSRI researchers develop new technique for modifying complex drug molecules

Chemists at The Scripps Research Institute have developed a versatile new technique for making modifications—especially one type of extremely difficult, but much-sought-after modification—to complex drug molecules.

18 Jan 2016

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made from an RNA that was previously believed to be a blank or non-coding RNA, suggesting there may be many other small 'non-coding' segments that play important biological roles.

18 Jan 2016

Scientists find new way to re-engineer body’s immune system to target cancer

Scientists have demonstrated a new way of re-engineering the body’s immune system to target cancer, paving the way for a new generation of drugs, unprecedented in safety and effectiveness.

18 Jan 2016

New BSR guidelines on prescribing anti-rheumatic medication during pregnancy, breastfeeding

The new BSR guidelines make a number of specific recommendations for the use of standard and/or biologic disease modifying anti-rheumatic drugs (DMARDs), providing crucial advice for clinicians, obstetricians and midwives.

18 Jan 2016

New study shows bone marrow lesions could help identify rapidly progressing osteoarthritis

A new study from the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, shows lesions, which can best be seen on MRI scans, could help identify individuals who are more likely to suffer from more rapidly progressing osteoarthritis.

18 Jan 2016

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

Novartis announced today that the US Food and Drug Administration has approved Cosentyx (secukinumab) for two new indications - the treatment of adult patients with active ankylosing spondylitis (AS) and active psoriatic arthritis (PsA).

17 Jan 2016

UHN's multi-disciplinary team successfully completes Canada's first transplant of the upper limb

In a Canadian first, a multi-disciplinary team, led by Dr. Steven McCabe, has successfully completed the country's first transplant of the upper limb.

13 Jan 2016

Common painkiller diclofenac has significant anti-cancer properties

Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers from the Repurposing Drugs in Oncology project.

12 Jan 2016

UTA researchers map out chemical mechanism of key enzyme found in autism, Alzheimer's and Down syndrome

Biochemists at The University of Texas at Arlington are mapping the catalytic processes of sulfur-oxidizing enzymes to improve understanding of the chemical imbalances found in patients with autism, Alzheimer's disease and Down syndrome.

11 Jan 2016

Patient recommendations for rheumatoid arthritis treatment: an interview with Dr Nowell

The study, “When patients write the guidelines: Patient panel recommendations for the treatment of RA,” published in Arthritis Research & Care, demonstrated the feasibility of developing CPG recommendations based on a voting panel composed entirely of patients.

8 Jan 2016

New, personalized approach to detecting low back pain

Scientists at The Feinstein Institute for Medical Research have discovered a new, personalized approach to diagnosing low back pain. The findings from a clinical study show that serum levels of the proinflammatory cytokine interleukin-6 (IL-6) vary in individuals with lumbar intervertebral disc disease and that biochemical profiling of circulating cytokines may assist in refining personalized diagnoses of disc diseases.

8 Jan 2016

$Major bone fracture may increase risk of widespread chronic body pain in later life$

Major bone fracture may increase risk of widespread chronic body pain in later life

Breaking a major bone may increase risk of widespread chronic body pain in later life, a new study has found.

6 Jan 2016

MUSC researchers receive PCORI grant to study safety, effectiveness of three blood-thinning drugs

A research team at the Medical University of South Carolina has been approved for a $13.5 million funding award by the Patient-Centered Outcomes Research Institute to study the safety and effectiveness of three blood-thinning drugs used to prevent potentially deadly blood clots in patients undergoing hip and knee replacement.

5 Jan 2016

New AARDA report highlights key issues and trends at State of Autoimmunity National Summit

What are the known environmental factors that trigger autoimmune disease and what are the latest technologies being developed to measure an individual's exposure to such risks?

29 Dec 2015

Arthritis News and Research

Latest Arthritis News and Research

Study throws light on why gout not well managed in many patients

Bariatric surgery prior to knee replacement benefits morbidly obese patients with end-stage osteoarthritis

Immunotherapy could be the future of cancer treatments

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Genetics play vital role in knee pain sensitivity

BENEPALI granted marketing authorization in the EU for treatment of chronic inflammatory diseases

TSRI researchers develop new technique for modifying complex drug molecules

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Scientists find new way to re-engineer body’s immune system to target cancer

New BSR guidelines on prescribing anti-rheumatic medication during pregnancy, breastfeeding

New study shows bone marrow lesions could help identify rapidly progressing osteoarthritis

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

UHN's multi-disciplinary team successfully completes Canada's first transplant of the upper limb

Common painkiller diclofenac has significant anti-cancer properties

UTA researchers map out chemical mechanism of key enzyme found in autism, Alzheimer's and Down syndrome

Patient recommendations for rheumatoid arthritis treatment: an interview with Dr Nowell

New, personalized approach to detecting low back pain

Major bone fracture may increase risk of widespread chronic body pain in later life

MUSC researchers receive PCORI grant to study safety, effectiveness of three blood-thinning drugs

New AARDA report highlights key issues and trends at State of Autoimmunity National Summit

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Arthritis News and Research

Latest Arthritis News and Research

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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