Arthritis News and Research

Latest Arthritis News and Research

Vertex reports interim data from VX-809 and KALYDECO combination Phase 2 study for cystic fibrosis

Vertex Pharmaceuticals Incorporated announced today an interim analysis of data from an ongoing Phase 2 study of VX-809 and KALYDECO (ivacaftor) that showed significant improvements in lung function (FEV1) among adults with cystic fibrosis (CF) who have two copies.

7 May 2012

Positive results from PROLOR Biotech's hGH-CTP Phase II trial for growth hormone deficiency

PROLOR Biotech, Inc. today reported top-line results from a Phase II four-month treatment extension study of hGH-CTP, its long-acting version of human growth hormone, in growth hormone deficient adults.

7 May 2012

Eye color linked to high-risk for skin conditions

Eye color may be an indicator of whether a person is high-risk for certain serious skin conditions. A study, led by the University of Colorado School of Medicine, shows people with blue eyes are less likely to have vitiligo.

7 May 2012

Human stem cells effective in treating muscular dystrophy

Researchers from the University of Minnesota's Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that - for the first time - makes the production of human muscle cells from stem cells efficient and effective.

5 May 2012

LRI applauds ACR colleagues for new lupus nephritis guidelines

The Lupus Research Institute (LRI) applauds our colleagues at the American College of Rheumatology (ACR) for issuing new guidelines to help healthcare professionals screen, diagnose and treat lupus nephritis, a type of kidney disease associated with lupus. Available on the ACR website, the new guidelines are just published in the April 2012 issue of Arthritis Care & Research.

5 May 2012

Researchers create new systematic assessment for malnutrition

A new systematic assessment of malnutrition, created by researchers at Penn State, will aid dietitians and other health care providers in diagnosis and treatment.

4 May 2012

Lexicon to receive funding for LX4211 Phase 2 trial in type 1 diabetes

Lexicon Pharmaceuticals, Inc. announced today that an independent, non-profit organization will provide funding to support the Phase 2 development of LX4211 in type 1 diabetes.

4 May 2012

One in six prescriptions may carry a medication error: GMC survey finds

A new study has found that more than one in six patients who are put on medication after seeing their GP are given a prescription containing an error. The study comes from the General Medical Council.

3 May 2012

Lexicon first quarter revenues decrease 50% to $0.3 million

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering breakthrough treatments for human disease, today updated its drug development progress and reported financial results for the three months ended March 31, 2012.

3 May 2012

SC formulation of Genentech’s ACTEMRA shows promise against RA

Genentech, a member of the Roche Group, today announced that the SUMMACTA study met its primary endpoint, showing comparable efficacy (non-inferiority) of the subcutaneous (SC) formulation of ACTEMRA (tocilizumab) 162mg weekly compared to 8 mg/kg ACTEMRA intravenous (IV) formulation every four weeks.

3 May 2012

Contemporary form of swaddling recommended to prevent dysplasia in infants

While tight swaddling may provide a newborn infant with a feeling of warmth and security, studies have found that regularly wrapping a child too tightly in a blanket or cloth may lead to an abnormal development of the hip joint, causing the ball of the hip to dislocate from the hip socket.

2 May 2012

Tips to help homeowners tick-proof their yards

For more than 250,000 Americans, the bite of a deer tick meant the start of a life changing disease. With record warm temperatures and the start of May's National Lyme Disease Awareness Month, Mosquito Squad is on watch and has six tips to help homeowners tick-proof their yards.

2 May 2012

Rigel first quarter net loss increases to $23.2 million

Rigel Pharmaceuticals, Inc. today reported financial results for the first quarter ended March 31, 2012.

2 May 2012

High-dose glucocorticoids double risk of bacterial infections in children with JIA

Children with juvenile idiopathic arthritis have higher rates of bacterial infection requiring hospitalization, and use of high-dose steroids significantly increases that risk, according to research from the University of Alabama at Birmingham.

2 May 2012

High-dose steroids increase infection risk in children with juvenile idiopathic arthritis

Children with juvenile idiopathic arthritis (JIA) have higher rates of hospitalized bacterial infection than children without JIA according to an observational study appearing in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

2 May 2012

Enrollment complete in Zalicus Synavive Phase 2b clinical trial for rheumatoid arthritis

Zalicus Inc., a biopharmaceutical company that discovers and develops novel treatments for patients suffering from pain and immuno-inflammatory diseases, today announced it has completed enrollment with 292 patients enrolled in the SYNERGY trial, a Phase 2b clinical trial designed to evaluate the safety and efficacy of Synavive, a low-dose glucocorticoid with the potential for amplified immuno-inflammatory benefits, in patients with rheumatoid arthritis (RA).

30 Apr 2012

Tolero granted exclusive global rights to commercialize MannKind's novel BTK compounds

Tolero Pharmaceuticals and MannKind Corporation today announced a license agreement granting Tolero exclusive worldwide rights to develop and commercialize compounds from MannKind's novel BTK (Bruton's tyrosine kinase) program, which are currently being developed for the treatment of hematological malignancies and inflammatory diseases.

30 Apr 2012

Anxiety more common than depression among people with arthritis

Researchers from the Centers for Disease Control and Prevention (CDC) found that one-third of U.S. adults with arthritis, 45 years and older, report having anxiety or depression. According to findings that appear today in Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR), anxiety is nearly twice as common as depression among people with arthritis, despite more clinical focus on the latter mental health condition.

30 Apr 2012

Study reveals direct correlation between negative thinking about pain and poor sleep

Chronic pain sufferers who learn to dwell less on their ailments may sleep better and experience less day-to-day pain, according to results of research conducted on 214 people with chronic face and jaw pain.

27 Apr 2012

FDA issues Complete Response Letter to Amgen’s sBLA for XGEVA

Amgen today announced that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter for the supplemental Biologics License Application (sBLA) for XGEVA (denosumab) to treat men with castration-resistant prostate cancer (CRPC) at high risk of developing bone metastases.

27 Apr 2012

Arthritis News and Research

Latest Arthritis News and Research

Vertex reports interim data from VX-809 and KALYDECO combination Phase 2 study for cystic fibrosis

Positive results from PROLOR Biotech's hGH-CTP Phase II trial for growth hormone deficiency

Eye color linked to high-risk for skin conditions

Human stem cells effective in treating muscular dystrophy

LRI applauds ACR colleagues for new lupus nephritis guidelines

Researchers create new systematic assessment for malnutrition

Lexicon to receive funding for LX4211 Phase 2 trial in type 1 diabetes

One in six prescriptions may carry a medication error: GMC survey finds

Lexicon first quarter revenues decrease 50% to $0.3 million

SC formulation of Genentech’s ACTEMRA shows promise against RA

Contemporary form of swaddling recommended to prevent dysplasia in infants

Tips to help homeowners tick-proof their yards

Rigel first quarter net loss increases to $23.2 million

High-dose glucocorticoids double risk of bacterial infections in children with JIA

High-dose steroids increase infection risk in children with juvenile idiopathic arthritis

Enrollment complete in Zalicus Synavive Phase 2b clinical trial for rheumatoid arthritis

Tolero granted exclusive global rights to commercialize MannKind's novel BTK compounds

Anxiety more common than depression among people with arthritis

Study reveals direct correlation between negative thinking about pain and poor sleep

FDA issues Complete Response Letter to Amgen’s sBLA for XGEVA

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Arthritis News and Research

Latest Arthritis News and Research

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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