Arthritis News and Research

Latest Arthritis News and Research

Amgen's Prolia receives FDA approval for new indications to treat cancer patients

Amgen today announced that the U.S. Food and Drug Administration (FDA) approved two new indications for Prolia® (denosumab) as a treatment to increase bone mass in women at high risk for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer and as a treatment to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for non-metastatic prostate cancer.

19 Sep 2011

New report finds decline in clinical trial recruitment for autoimmune disorders

The number of patients recruited to clinical trials for autoimmune disorders has waned in the last ten years, according to a new report available on companiesandmarkets.com.

19 Sep 2011

Power wheelchairs are not 'government waste', they give freedom and independence to people with disabilities

"The public would be better served if policymakers left their desks in Washington and met with us in our homes, where every day is a struggle."

17 Sep 2011

Novel therapies remove the brakes cancer puts on the immune system

Some of the newest therapies in the war on cancer remove the brakes cancer puts on the immune system, Georgia Health Sciences University researchers report.

17 Sep 2011

Novartis reports positive results from first pivotal ACZ885 Phase III trial in systemic juvenile idiopathic arthritis

Novartis announced today positive results of the first pivotal Phase III trial of ACZ885 in patients with systemic juvenile idiopathic arthritis (SJIA), a rare and serious childhood auto-inflammatory disease. The results, presented at the 2011 European Pediatric Rheumatology Congress in Bruges, Belgium, showed all primary and secondary endpoints of the study were met.

17 Sep 2011

New insight into how nervous system regulates immunity

Scientists have identified a surprising new role for a new type of T cell in the immune system: some of them can be activated by nerves to make a neurotransmitter (acetylcholine) that blocks inflammation. The discovery of these T cells is novel and suggests that it may be possible to treat inflammation and autoimmune diseases by targeting the nerves and the T cells. The study was published this week in Science.

17 Sep 2011

Adult stem cells hold hope for treatment of lupus

With a patient's own adult stem cells, there is new hope for the intractable autoimmune disease lupus - systemic lupus erythematosus (SLE) - which is difficult to cure.

17 Sep 2011

Positive results from PROLOR Biotech's Factor VIIa-CTP preclinical study on hemophilia

PROLOR Biotech, Inc.,, today reported positive results from a comparative study of its biobetter longer-acting version of the hemophilia drug Factor VIIa (Factor VIIa-CTP) in hemophilic mice.

15 Sep 2011

UIC researchers to conduct study on televised drug commercials

Do pharmaceutical ads educate patients and improve health -- or merely spur drug sales? Researchers at the University of Illinois at Chicago's Institute for Health Research and Policy will conduct the first comprehensive study of televised drug commercials using Nielsen Media Research and health care utilization data.

15 Sep 2011

Roundup: N.J. Governor opts not to cut Medicaid rolls; Seattle council mandates sick leave

Thousands of New Jersey's working poor will keep their health insurance under a new administration proposal to restructure Medicaid, abandoning a controversial plan that would have drastically reduced the number of eligible recipients.

14 Sep 2011

Lexicon's LX4211 clinical data presented at EASD annual meeting

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering breakthrough treatments for human disease, announced today that the company is presenting clinical data this week at the European Association for the Study of Diabetes (EASD) annual meeting in Lisbon, Portugal.

14 Sep 2011

Older drugs may be better than newly approved ones

It is a common belief that drugs given the okay by the Food and Drug Administration (FDA) are safer and more effective than they have to be to win approval, according to a new study. Especially in the first few years after a drug becomes available, researchers note, there are still questions about how well it will work and whether it will have any serious side effects warn experts. For example FDA-approved painkiller Vioxx was pulled off the market in 2004 after longer-term evidence showed that it may increase the risk of heart attack and stroke.

13 Sep 2011

Human gliomas release excess levels of glutamate and trigger seizures

Glioma, one of the most deadly and common types of brain tumor, is often associated with seizures, but the origins of these seizures and effective treatments for them have been elusive. Now a team funded by the National Institutes of Health has found that human gliomas implanted in mice release excess levels of the brain chemical glutamate, overstimulating neurons near the tumor and triggering seizures.

12 Sep 2011

Study pinpoints relationship between primary brain tumors and onset of epileptic seizures

New research from the University of Alabama at Birmingham pinpoints the relationship between primary brain tumors and the onset of epileptic seizures and reveals that a drug used to treat Crohn's disease inhibits those seizures and may be able to slow a tumor's growth.

12 Sep 2011

Nektar announces positive results from NKTR-102 Phase 2 study on metastatic breast cancer

Nektar Therapeutics announced today that positive results from the company's Phase 2 clinical study of NKTR-102 in patients with metastatic breast cancer were presented at the ASCO 2011 Breast Cancer Symposium in San Francisco, California.

12 Sep 2011

Researchers identify bouncer protein that plays a vital role in RA prevention

Researchers at Northwestern University Feinberg School of Medicine have discovered why the immune cells of people with rheumatoid arthritis become hyperactive and attack the joints and bones. The immune cells have lost their bouncer, the burly protein that keeps them in line the same way a bouncer in a nightclub controls rowdy patrons.

8 Sep 2011

Cam impingement may increase risk of hip OA in young men

Hip impingement may be a risk factor of osteoarthritis (OA) of the hip. A new study reveals that the presence of an underlying deformity, known as cam impingement, is associated with hip damage in young men without any arthritis symptoms and detected using magnetic resonance imaging.

8 Sep 2011

Ardea Biosciences reports positive outcome from lesinurad End-of-Phase 2 meetings with FDA

Ardea Biosciences, Inc. announced that it has completed formal End-of-Phase 2 meetings with the U.S. Food and Drug Administration (FDA) and successfully reached agreement on the following key aspects of its proposed lesinurad Phase 3 development plan: the overall size and design of the planned Phase 3 clinical studies, the primary endpoints, the total safety database proposed for NDA filing, manufacturing plans for both drug substance and drug product, the preclinical toxicology program and the clinical pharmacology program.

7 Sep 2011

Researchers investigate special diets that could help youngsters keep the weight off

A shocking 17 per cent of boys and 15 per cent of girls aged two to 15 years are obese in the UK, putting them at risk of serious, long-term health problems. Now a team of Aberdeen researchers are investigating special diets which could help youngsters keep the weight off, thanks to a grant from children's charity Action Medical Research.

7 Sep 2011

Duodenal switch may lead to more weight loss but more complications: Study

A less usual and common type of obesity surgery may spur more weight loss than its far more popular cousin, gastric bypass - but at the price of greater long-term risks, researchers reported.

6 Sep 2011

Arthritis News and Research

Latest Arthritis News and Research

Amgen's Prolia receives FDA approval for new indications to treat cancer patients

New report finds decline in clinical trial recruitment for autoimmune disorders

Power wheelchairs are not 'government waste', they give freedom and independence to people with disabilities

Novel therapies remove the brakes cancer puts on the immune system

Novartis reports positive results from first pivotal ACZ885 Phase III trial in systemic juvenile idiopathic arthritis

New insight into how nervous system regulates immunity

Adult stem cells hold hope for treatment of lupus

Positive results from PROLOR Biotech's Factor VIIa-CTP preclinical study on hemophilia

UIC researchers to conduct study on televised drug commercials

Roundup: N.J. Governor opts not to cut Medicaid rolls; Seattle council mandates sick leave

Lexicon's LX4211 clinical data presented at EASD annual meeting

Older drugs may be better than newly approved ones

Human gliomas release excess levels of glutamate and trigger seizures

Study pinpoints relationship between primary brain tumors and onset of epileptic seizures

Nektar announces positive results from NKTR-102 Phase 2 study on metastatic breast cancer

Researchers identify bouncer protein that plays a vital role in RA prevention

Cam impingement may increase risk of hip OA in young men

Ardea Biosciences reports positive outcome from lesinurad End-of-Phase 2 meetings with FDA

Researchers investigate special diets that could help youngsters keep the weight off

Duodenal switch may lead to more weight loss but more complications: Study

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Arthritis News and Research

Latest Arthritis News and Research

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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