Bipolar Disorder News and Research

Latest Bipolar Disorder News and Research

UCI researchers uncover new underlying factor of seizures

University of California, Irvine researchers with the School of Medicine have identified the mechanism by which valproic acid controls epileptic seizures, and by doing so, also revealed an underlying factor of seizures.

15 Sep 2015

Antidepressants can increase depression, mood cycling in rapid-cycling bipolar disorder patients

In patients with rapid-cycling bipolar disorder, antidepressants can increase incidents of depression and mood cycling. Rif S. El-Mallakh, M.D., director of the Mood Disorders Clinical and Research Program at the University of Louisville, along with Nassir Ghaemi, M.D., of Tufts University and other researchers, conducted the first randomized clinical trial that analyzes how modern antidepressants affect patients with rapid-cycling (RC) bipolar disorder (BD).

15 Sep 2015

Researchers examine neuroanatomical signature of schizophrenia in different ethnic groups

While it is known that the incidence and outward symptoms of schizophrenia are strongly influenced by ethnic factors--for instance, patients from Asian ethnicities are more likely to experience visual hallucinations, whereas patients from western cultures and Caucasian ethnicities are more likely to suffer from auditory hallucinations--it was unclear if brain deficits would differ amongst suffers from various ethnic backgrounds.

14 Sep 2015

Ex-prisoners with common psychiatric disorders more likely to commit violent crimes after release

Ex-prisoners with common psychiatric disorders such as bipolar disorder (manic-depressive disorder) and alcohol and drug abuse are substantially more likely to commit a violent crime after release than other prisoners, according to new research published in The Lancet Psychiatry journal.

4 Sep 2015

Brain scans may help predict patients' response to antipsychotic drug treatment

Investigators at The Feinstein Institute for Medical Research have discovered that brain scans can be used to predict patients' response to antipsychotic drug treatment. The findings are published online in the latest issue of The American Journal of Psychiatry.

28 Aug 2015

UiO researchers test new nasal spray device for treating mental illness

Researchers at the University of Oslo have tested a new device for delivering hormone treatments for mental illness through the nose. This method was found to deliver medicine to the brain with few side effects.

27 Aug 2015

Psychiatric disorders may follow trigeminal neuralgia

Patients with trigeminal neuralgia have an increased risk of later developing certain psychiatric disorders, a population-based study suggests.

21 Aug 2015

Medicaid could save billions as patents for several blockbuster antipsychotic medications expire

Medicaid is expected to save billions of dollars a year as patents for several blockbuster antipsychotic medications expire and use of generic versions of these drugs increases, according to a new study by researchers at the University of Maryland School of Medicine. These savings may provide relief from the high costs of these medications and allow policymakers to lift restrictions on patients' access, the researchers argue.

21 Aug 2015

Physicians may now have tools to predict people at greater risk of attempting suicide

People being treated for bipolar disorder and other psychiatric illnesses are at greater risk of attempting suicide, but physicians may now have tools to predict which of those individuals will attempt it and intervene early to prevent such tragedies from occurring.

18 Aug 2015

Neurocrine completes enrollment in Phase III clinical trial of NBI-98854 in tardive dyskinesia patients

Neurocrine Biosciences, Inc. announced today that it has recently completed subject randomization of the Phase III clinical trial (Kinect 3 Study) of its proprietary Vesicular Mono-Amine Transporter 2 (VMAT2) compound NBI-98854 in tardive dyskinesia patients.

13 Aug 2015

FDA accepts sNDA to review Brintellix clinical trial data for treatment of major depressive disorder

Takeda Pharmaceutical Company Limited (Takeda) and H. Lundbeck A/S (Lundbeck) announced today the U.S. Food and Drug Administration (FDA) has accepted a supplemental New Drug Application (sNDA) for review to add clinical data regarding the effect of Brintellix (vortioxetine) on certain aspects of cognitive function in adults with Major Depressive Disorder (MDD) to the current product label.

11 Aug 2015

DISC-1: schizophrenia's "Rosetta Stone" gene? An interview with Professor Kevin Fox

The DISC-1 gene has been studied intensively over the years because people with mutations in DISC1 have a high likelihood of mental illness. DISC-1 was known to be associated with schizophrenia, bipolar disorder, major clinical depression and autism.

10 Aug 2015

Mice without specific brain chemical develop characteristics similar to bipolar disorder, shows study

Mice that have a particular brain chemical switched off become hyperactive and sleep for just 65 per cent of their normal time.

29 Jul 2015

Low-dose lithium lowers involuntary motor movements in mouse model of Parkinson's disease

Low-dose lithium reduced involuntary motor movements - the troubling side effect of the medication most commonly used to treat Parkinson's disease (PD) - in a mouse model of the condition that is diagnosed in about 60,000 Americans each year. The third in a series of studies from the Andersen lab involving PD and low-dose lithium, the results add to mounting evidence that low-doses of the psychotropic drug could benefit patients suffering from the incurable, degenerative condition.

28 Jul 2015

Diagnosing psychiatric disorder may not be as important as prescribing effective treatment

Nailing the diagnosis of a psychiatric disorder may not be important in prescribing effective treatment, according to Mark Zimmerman, M.D., a clinical researcher at Rhode Island Hospital. His opinion editorial was published online today in the Journal of Clinical Psychiatry.

24 Jul 2015

Breakthrough reveals influence of schizophrenia’s 'Rosetta Stone' gene in brain development

Scientists have identified a critical function of what they believe to be schizophrenia's "Rosetta Stone" gene that could hold the key to decoding the function of all genes involved in the disease.

24 Jul 2015

New approach holds great promise for developing effective treatments for human mitochondrial diseases

Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases.

21 Jul 2015

Allergan announces U.S. availability of SAPHRIS 2.5 mg tablets for children with bipolar I disorder

Allergan plc today announced that SAPHRIS (asenapine) 2.5 mg sublingual (placed under the tongue) black-cherry flavored tablets are available in pharmacies throughout the U.S. In March 2015, the U.S. Food and Drug Administration approved SAPHRIS for the acute treatment of manic or mixed episodes associated with bipolar I disorder in pediatric patients (ages 10 – 17).

17 Jul 2015

New study shows that lithium chloride could be used to treat arthritis

Lithium chloride which is used as a mood stabiliser in the treatment of mental health problems, mainly bipolar disorder, could be used to treat arthritis according to a new study.

16 Jul 2015

Gene function in the human brain could help reveal basis of autism

UNSW Australia scientists have discovered a link between autism and genetic changes in some segments of DNA that are responsible for switching on genes in the brain.

14 Jul 2015

Bipolar Disorder News and Research

Latest Bipolar Disorder News and Research

UCI researchers uncover new underlying factor of seizures

Antidepressants can increase depression, mood cycling in rapid-cycling bipolar disorder patients

Researchers examine neuroanatomical signature of schizophrenia in different ethnic groups

Ex-prisoners with common psychiatric disorders more likely to commit violent crimes after release

Brain scans may help predict patients' response to antipsychotic drug treatment

UiO researchers test new nasal spray device for treating mental illness

Psychiatric disorders may follow trigeminal neuralgia

Medicaid could save billions as patents for several blockbuster antipsychotic medications expire

Physicians may now have tools to predict people at greater risk of attempting suicide

Neurocrine completes enrollment in Phase III clinical trial of NBI-98854 in tardive dyskinesia patients

FDA accepts sNDA to review Brintellix clinical trial data for treatment of major depressive disorder

DISC-1: schizophrenia's "Rosetta Stone" gene? An interview with Professor Kevin Fox

Mice without specific brain chemical develop characteristics similar to bipolar disorder, shows study

Low-dose lithium lowers involuntary motor movements in mouse model of Parkinson's disease

Diagnosing psychiatric disorder may not be as important as prescribing effective treatment

Breakthrough reveals influence of schizophrenia’s 'Rosetta Stone' gene in brain development

New approach holds great promise for developing effective treatments for human mitochondrial diseases

Allergan announces U.S. availability of SAPHRIS 2.5 mg tablets for children with bipolar I disorder

New study shows that lithium chloride could be used to treat arthritis

Gene function in the human brain could help reveal basis of autism

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Bipolar Disorder News and Research

Latest Bipolar Disorder News and Research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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