Breast Cancer News and Research

Latest Breast Cancer News and Research

Gene subnetworks provide new prognostic markers for breast cancer

The metastasis or spread of breast cancer to other tissues in the body can be predicted more accurately by examining subnetworks of gene expression patterns in a patient's tumor, than by conventional gene expression microarrays, according to a presentation at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

15 Dec 2008

Fruits, vegetables and fiber may cut risk of breast cancer recurrence in women without hot flashes

A secondary analysis of a large, multicenter clinical trial has shown that a diet loaded with fruits, vegetables and fiber and somewhat lower in fat compared to standard federal dietary recommendations cuts the risk of recurrence in a subgroup of early-stage breast cancer survivors - women who didn't have hot flashes - by approximately 31 percent.

15 Dec 2008

Breast cancer genome shows instability of cancer

A newly published genome sequence of a breast cancer cell line reveals a heavily rearranged genetic blueprint involving breaks and fusions of genes and a broken DNA repair machinery, said researchers at Baylor College of Medicine in a report that appears online in the journal Genome Research.

15 Dec 2008

Computer-aided detection (CAD) mammography for breast cancer screening

Computer programs designed to help radiologists could identify more cases of breast cancer, but they might also increase the number of false-positive results, which can lead to biopsies in healthy women, according to a recent systematic review.

15 Dec 2008

New research moves us one step closer to personalised breast cancer treatment

Cancer Research UK scientists have found that a test, already used in breast cancer diagnosis, can also predict who will and who won't benefit from commonly used chemotherapy drugs.

15 Dec 2008

How tamoxifen prevents breast cancer in some women but not others

The power of the drug tamoxifen to reduce breast density is key in preventing breast cancer - according to a presentation in America by Cancer Research UK scientists.

15 Dec 2008

Three studies of bioTheranostics molecular breast cancer diagnostics presented at symposium

bioTheranostics, a bioMerieux company that discovers, develops and commercializes new molecular diagnostic tests in oncology, reported today findings from three studies using the company's molecular breast cancer assay to predict risk of disease recurrence in individual patients.

14 Dec 2008

Tau protein expression predicts breast cancer survival in an unexpected way

Expression of the microtubule-binding protein Tau is not a reliable means of selecting breast cancer patients for adjuvant paclitaxel chemotherapy, according to research led by The University of Texas M. D. Anderson Cancer Center.

14 Dec 2008

Doxil and docetaxel combination treatment delays disease progression in metastatic breast cancer

Results from a Phase 3 study show that patients with metastatic breast cancer who were treated previously with an anthracycline in the adjuvant setting experienced a significant improvement in time to disease progression (TTP) and overall response rates after receiving a combination of DOXIL (doxorubicin HCl liposome injection) and docetaxel as compared to docetaxel alone.

14 Dec 2008

Planned safety analysis of a breast cancer prevention study reveals encouraging news for Exemestane

An interim analysis of a breast cancer prevention study using exemestane (Aromasin) finds an "acceptable" level of bone loss.

14 Dec 2008

Zometa (zoledronic acid) shown to enhance chemotherapy in reducing breast tumor size

New data released demonstrates that the addition of Zometa (zoledronic acid) injection to standard chemotherapy before breast cancer surgery reduces the size of breast tumors more effectively than chemotherapy alone in women with early-stage disease.

14 Dec 2008

Having dense breasts increases breast cancer risk

Having dense breasts - areas that show up light on a mammogram - is strongly associated with increased breast cancer risk, but "why" remains to be answered.

14 Dec 2008

Postmenopausal patients being considered for tamoxifen therapy should be tested for CYP2D6 gene deficiency

Findings from a new study have prompted Mayo Clinic researchers to recommend CYP2D6 gene testing for postmenopausal women about to begin tamoxifen therapy.

14 Dec 2008

Femara shows reduced risk of death versus tamoxifen after breast cancer surgery

Femara showed reduced risk of death by 13% (P=0.08) versus tamoxifen, despite inclusion of patients who had switched over from tamoxifen to Femara during the study period, following the study's unblinding.

14 Dec 2008

Exciting cancer discovery

Metastasis is the ability of cancer cells to spread from a primary site, to form tumours at distant sites.

14 Dec 2008

Early-stage breast cancer patients with HER2 positive tumors at increased risk of recurrence

Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, according to a study led by researchers at The University of Texas M. D. Anderson Cancer Center.

14 Dec 2008

Atypical hyperplasia increases risk of developing breast cancer

A type of benign breast disease (BBD) known as atypical hyperplasia substantially increases a young woman's risk of developing breast cancer, even if there is no history of breast cancer in her family, say researchers at Mayo Clinic.

14 Dec 2008

Magnetic resonance imaging alternated with mammography may be best for high-risk women

Magnetic resonance imaging (MRI) alternated with mammography at six-month intervals can detect breast cancers not identified by mammography alone, a research team from The University of Texas M. D. Anderson Cancer Center will report at the 31st at the CRTC-AACR San Antonio Breast Cancer Symposium.

14 Dec 2008

Aromatase inhibitors most effective in preventing breast cancer from coming back

Two separate meta-analyses of clinical trials from around the world that tested tamoxifen against aromatase inhibitor drugs in postmenopausal women with early breast cancer have each reached the same conclusion: aromatase inhibitors are more effective in preventing breast cancer from coming back.

12 Dec 2008

Researchers find tamoxifen's power comes from endoxifen

Mayo Clinic researchers have discovered that a chemical known as endoxifen appears to be the primary metabolite responsible for the effectiveness of tamoxifen in treating breast cancer, and that it works against cancer in an entirely unexpected way.

12 Dec 2008

Breast Cancer News and Research

Latest Breast Cancer News and Research

Gene subnetworks provide new prognostic markers for breast cancer

Fruits, vegetables and fiber may cut risk of breast cancer recurrence in women without hot flashes

Breast cancer genome shows instability of cancer

Computer-aided detection (CAD) mammography for breast cancer screening

New research moves us one step closer to personalised breast cancer treatment

How tamoxifen prevents breast cancer in some women but not others

Three studies of bioTheranostics molecular breast cancer diagnostics presented at symposium

Tau protein expression predicts breast cancer survival in an unexpected way

Doxil and docetaxel combination treatment delays disease progression in metastatic breast cancer

Planned safety analysis of a breast cancer prevention study reveals encouraging news for Exemestane

Zometa (zoledronic acid) shown to enhance chemotherapy in reducing breast tumor size

Having dense breasts increases breast cancer risk

Postmenopausal patients being considered for tamoxifen therapy should be tested for CYP2D6 gene deficiency

Femara shows reduced risk of death versus tamoxifen after breast cancer surgery

Exciting cancer discovery

Early-stage breast cancer patients with HER2 positive tumors at increased risk of recurrence

Atypical hyperplasia increases risk of developing breast cancer

Magnetic resonance imaging alternated with mammography may be best for high-risk women

Aromatase inhibitors most effective in preventing breast cancer from coming back

Researchers find tamoxifen's power comes from endoxifen

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Breast Cancer News and Research

Latest Breast Cancer News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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