Cancer News and Research

Latest Cancer News and Research

Switching treatment to exemestane after 2-3 years on tamoxifen, improves survival

The Intergroup Exemestane Study (IES), an extensive, international study, tested the superiority of switching to exemestane (an aromatase inhibitor) from tamoxifen in patients with early breast cancer.

13 Feb 2007

Variation in gene caspase-8 may help protect against breast cancer

A large-scale analysis of data on breast cancer risk has concluded that a common variation in the gene caspase-8 (CASP8) is associated with a somewhat lower risk of the disease. Variants are small changes that occur in a gene sequence.

13 Feb 2007

Breast cancer survival rates improved by novel drug sequence

Changing the way women are treated for breast cancer could improve their overall chance of survival, according to research published in the Lancet.

13 Feb 2007

Texas lawmakers ask Gov. Perry to rescind order mandating HPV vaccination for girls entering sixth grade

Thirty-two Texas lawmakers last Thursday sent a letter to Gov. Rick Perry (R) reiterating their plea for him to rescind an executive order that would mandate vaccination against human papillomavirus for girls entering the sixth grade, the AP/Dallas Morning News reports.

13 Feb 2007

Women who donate eggs for stem cell research face few health risks

Women who donate their eggs for stem cell research or in vitro fertilization are not at increased risk of health complications, and most of the risks are a result of the hormones used to stimulate their bodies to release more than one egg, according to a report commissioned by the California Institute of Regenerative Medicine and released by the Institute of Medicine, Bloomberg reports.

13 Feb 2007

Actions taken on HPV vaccine proposals in Alabama, Louisiana, Utah, Washington

The following highlights recent news of state actions on human papillomavirus vaccine proposals. Merck's HPV vaccine Gardasil and GlaxoSmithKline's HPV vaccine Cervarix in clinical trials have been shown to be 100% effective in preventing infection with HPV strains 16 and 18, which together cause about 70% of cervical cancer cases.

13 Feb 2007

Healthier wines

A new technique that uses ozone to preserve grapes could help prevent allergies and boost healthy compounds at the same time, reports Jennifer Rohn in Chemistry & Industry, the magazine of the Society of Chemical Industry.

12 Feb 2007

Targeting bladder tumor cells in vivo and in the urine with a peptide identified by phage display

Efforts to create nanoparticles that deliver anticancer drugs or imaging agents to tumors while avoiding healthy cells are often stymied by a lack of known tumor targets, that is, molecules found on the surface of malignant cells but not healthy cells.

12 Feb 2007

Nanoparticle boost for antitumor vaccines

Researchers have known for some time that certain sequences of synthetic DNA induce potent immune responses when injected into animals and humans.

12 Feb 2007

Nanotechnology and the public: Effectively communicating nanoscale science and engineering concepts

If you could paint a gallon's worth of paint one nanometer thick, how much area could you cover?

12 Feb 2007

Natural gum improves gold nanoparticles for cancer imaging

Gold nanoparticles have shown significant promise as agents to detect and treat cancer, but researchers have had difficulty creating gold nanoparticles that have suitable pharmacological properties for use in humans.

12 Feb 2007

DNA-encoded antibody libraries

During the past several years, breakthroughs in genomic and proteomic technologies have enabled researchers to more clearly identify the biochemical networks that malfunction when a healthy cell becomes malignant.

12 Feb 2007

Cancer breakthrough - first treatment to directly target tumor supply

For the first time, physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City have demonstrated in patients the ability of an antibody to directly target the blood supply of a wide variety of tumors, leaving healthy tissues unharmed.

12 Feb 2007

Combination drug treatment helps beat mesothelioma

People with mesothelioma - a form of cancer associated with asbestos exposure - have a higher survival rate when treated with a combination of two cancer drugs, a large multicenter study finds.

12 Feb 2007

Switching to an aromatase inhibitor provides mortality benefit in early breast carcinoma

For breast cancer patients taking tamoxifen, switching to an aromatase inhibitor within three years significantly improves survival rates, according to a new study.

12 Feb 2007

Changes in breast cancer management

Aggressive research currently underway brings hope of dramatic advances in breast cancer management, according to a new review.

12 Feb 2007

PALB2 gene mutation elevates risk of breast cancer four-fold

Cancer is a complex and common disease caused by a combination of both genetic and environmental factors. An inherited predisposition seems to be involved in at least 5-10 per cent of all cases of breast cancer.

11 Feb 2007

Rate of stem cell transplants among African-Americans lower

Lower transplant rates in ethnic communities may be explained somewhat by a lack of suitable anonymous donors, a problem the medical community has long known and been working to address. Surprisingly, the study found the discrepancy in treatment held true even when the transplant was autologous (e.g. self-donated stem cells were used) or when the cells were donated by a relative, typically a sibling.

11 Feb 2007

South Africa starts major HIV/AIDS vaccine trial

The launch of the first large-scale study to evaluate a candidate HIV vaccine on the African continent was announced today by study collaborators in the United States and South Africa. The trial will involve up to 3,000 participants at five sites throughout South Africa and is expected to continue for four years.

11 Feb 2007

Researchers discover master switch for a tumor suppressive network

A decades-old cancer mystery has been solved by researchers at Cold Spring Harbor Laboratory (CSHL). "We not only found a critical tumor suppressor gene, but have revealed a master switch for a tumor suppressive network that means more targeted and effective cancer therapy in the future," said CSHL Associate Professor Alea Mills, Ph.D.

11 Feb 2007