Cancer News and Research

Latest Cancer News and Research

NYU Langone IBD Center celebrates two years of transforming lives

A complex, chronic, and debilitating condition, inflammatory bowel disease (IBD) affects roughly 3 million Americans, including those with Crohn's disease and ulcerative colitis.

16 Dec 2024

A new era of targeted therapy with antibody–drug conjugates

TBC

From Sino Biological Inc. 16 Dec 2024

Fairjourney Biologics establishes Scientific Advisory Board

FairJourney Biologics S.A., leaders in the discovery and optimization of antibodies, today announced it has established a Scientific Advisory Board (SAB) to support its strategy for ongoing growth and innovation.

16 Dec 2024

Study reveals tumor and immune cell interactions in craniopharyngiomas

Craniopharyngiomas are brain tumors that negatively impact the hormonal function of the nearby pituitary.

16 Dec 2024

How AI is advancing mammographic density-based breast cancer risk prediction

Innovative AI techniques are uncovering mammographic features that enhance breast cancer risk prediction, crucial for effective screening and risk mitigation.

16 Dec 2024

Global study reveals shifting trends in ovarian cancer incidence by subtype and region

Study analyzed global patterns and trends in ovarian cancer incidence from 1988 to 2017, highlighting variations by histological subtypes and regions. It revealed significant geographic disparities, with higher rates in regions with very high HDIs and emphasized the need for targeted prevention and surveillance strategies.

15 Dec 2024

Research sheds light on how hypoxia affects T cell function in cancer

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective.

14 Dec 2024

Research finds no change in mortality despite platinum chemotherapy shortage

During a shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023, there was no difference in mortality rates among patients with advanced cancer compared to the previous year, and prescription rates for the two drugs fell less than three percent overall - and 15.1 percent at the peak - according to an analysis published this week in the Journal of the National Cancer Institute by researchers from the University of Pennsylvania's Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

14 Dec 2024

Dietary adjustments may help control prostate cancer in men undergoing active surveillance

A new study led by UCLA Health Jonsson Comprehensive Cancer Center investigators offers new evidence that dietary changes may help reduce cancer cell growth in patients undergoing active surveillance, a treatment approach that involves regular monitoring of the cancer without immediate intervention.

14 Dec 2024

Australian research unlocks new path for cancer immunotherapy

Australian-led research is unlocking new ways for immunotherapy to better target cancer.

14 Dec 2024

Promising combination therapy could improve liver cancer outcomes

Dan G. Duda, DMD, PhD, of the Edwin L. Steele Laboratories for Tumor Biology and Department of Radiation Oncology at Massachusetts General Hospital, is the corresponding author of a paper published in Cancer Immunology Research, "Combination CXCR4 and PD1 Blockade Enhances Intratumoral Dendritic Cell Activation and Immune Responses Against Hepatocellular Carcinoma."

14 Dec 2024

Genetic insights into reproductive health and longevity

Led by researchers from the University of Oxford's Leverhulme Centre for Demographic Science and the University of Iceland, the review explores how genetic variations can explain differences in reproductive health and longevity.

14 Dec 2024

Gene variant in Andean populations could help predict blood cancer treatment outcomes

Two researchers from Huntsman Cancer Institute at the University of Utah (the U) have discovered a gene variant found in high-altitude Andean populations that they believe could be a new biomarker for predicting the severity of diseases and treatment responses for certain types of blood cancer.

14 Dec 2024

ZEST trial fails to meet enrollment goals for ctDNA testing in breast cancer

The ZEST clinical trial, designed to evaluate niraparib (Zejula) for the prevention of breast cancer recurrence in patients with circulating tumor DNA (ctDNA), failed to accrue enough patients positive for ctDNA, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

Study unveils key mechanism behind prostate cancer's uncontrolled growth

Prostate cancer hijacks the normal prostate's growth regulation program to release the brakes and grow freely, according to Weill Cornell Medicine researchers.

14 Dec 2024

Machine learning model predicts CDK4/6 inhibitor effectiveness in metastatic breast cancer

A machine learning (ML) model incorporating both clinical and genomic factors outperformed models based solely on either clinical or genomic data in predicting which patients with hormone receptor (HR)-positive, HER2-negative metastatic breast cancer would have better outcomes from adding CDK4/6 inhibitors to endocrine therapy as first-line treatment, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

Targeted gene therapy shuts down cancer cells' energy centers

Researchers are shining a light on cancer cells' energy centers – literally – to damage these power sources and trigger widespread cancer cell death.

14 Dec 2024

Adjuvant anthracycline- plus taxane-based chemotherapy regimen improves survival in high-risk breast cancer patients

Patients with early-stage, node-negative, hormone receptor (HR)-positive, HER2- negative breast cancer who have a high risk of recurrence based on the OncotypeDX genomic test had better outcomes when treated with adjuvant anthracycline- plus taxane-based chemotherapy regimens compared with those receiving adjuvant taxane-based chemotherapy regimens alone, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

CNIC team develops a comprehensive set of genetic tools and mouse lines

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a comprehensive set of innovative genetic tools and mouse lines, called iFlpMosaics, designed to enhance the study of gene function and its implications in health and disease.

14 Dec 2024

Exploring the cytotoxic potential of neocryptolepine derivatives against cancer

Announcing a new publication for Acta Materia Medica journal. Cancer has been a severe public health and social problem, a leading disease that has diminished the quality of life, and a barrier to improving life expectancy.

13 Dec 2024