Cannabinoid

Cannabinoids are a group of terpenophenolic compounds present in Cannabis (''Cannabis sativa'') and occur naturally in the nervous and immune systems of animals.

What are Cannabinoids?

Cannabinoids are naturally occurring compounds found in the Cannabis sativa plant. Of over 480 different compounds present in the plant, only around 66 are termed cannabinoids.

Synthetic and Patented Cannabinoids

Pharmacology of Cannabinoid Receptors

The Immunological Effects of Cannabinoids

Crystal Structure of the Human Cannabinoid Receptor CB2

A Failed Cannabis Hair Test - How Topical Application Results in Cannabinoid Incorporation

Does CBD Oil Work for Arthritis Pain?

Latest Cannabinoid News and Research

Understanding the mechanisms behind alcohol-associated liver disease

A newly published review in eGastroenterology compiles recent research on alcohol-associated liver disease (ALD), offering an overview of its pathogenesis and efforts to better understand this condition.

19 Dec 2024

Pioneering study shows promising results for cognitive treatment in Down syndrome

The ICOD (Improving Condition in Down syndrome) project, a pioneering study in addressing the cognitive difficulties associated with Down syndrome, has demonstrated the safety of treatment with the molecule AEF0217, developed by the French biotech Aelis Farma, as well as its effectiveness in improving cognitive function in these people.

17 Dec 2024

Targeting brain enzyme may offer new treatment for obesity

Endocannabinoids in the brain play a key role in food intake and energy use. Modulating the action of these molecules could help fight obesity, say researchers at Université de Montréal's affiliated hospital research center.

16 Dec 2024

Boosting endocannabinoids could reduce opioid addiction risk

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ability to relieve pain, according to Weill Cornell Medicine investigators working with researchers from The Center for Youth Mental Health at NewYork-Presbyterian.

2 Dec 2024

Study links cannabis use to genotoxicity and transgenerational health impacts

Cannabis exposure leads to genetic damage and accelerated aging, raising concerns about its transgenerational health effects and public health implications.

18 Nov 2024

EASI algorithm set to transform forensic drug identification processes

Relief is coming for crime scene investigators and toxicologists who have struggled to accurately and swiftly identify drugs that have been seized by law enforcement and may be relied on as evidence at trial, thanks to a research partnership between West Virginia University and the U.S. Drug Enforcement Administration.

15 Nov 2024

Cannabinol enhances sleep in rats, study shows

Research by scientists at the University of Sydney has identified a constituent in the cannabis plant that improves sleep.

11 Nov 2024

Study questions causal link between cannabis and brain changes

Lifetime cannabis use is associated with several changes in brain structure and function in later life, suggests an observational study, but these associations may not be causal, finds a genetic analysis of the same data, published in the open access journal BMJ Mental Health.

30 Oct 2024

Prenatal exposure to cannabinoids impacts adult health in rats

Scientists who exposed pregnant rats to a synthetic cannabinoid that activates the same receptors in the brain as marijuana detected effects of the drug on their offspring, such as cardiovascular problems in females and augmented susceptibility to panic attacks in males, and showed that these adverse effects persisted into adulthood.

3 Oct 2024

High linoleic acid intake during pregnancy may harm fetal growth and raise obesity risk

High maternal linoleic acid intake during pregnancy may impact fetal development and increase the risk of obesity and inflammation in offspring. However, more research is needed to fully understand these effects in humans.

10 Sep 2024

Calorie reduction doesn't hinder exercise in mice, new research finds

A new UC Riverside study demonstrates that calorie restriction doesn't deter mice from exercising, challenging the belief that dieting drains workout energy.

9 Aug 2024

Study finds cannabigerol effectively reduces anxiety, boosts memory recall

A lesser-known cannabinoid that is gaining in popularity Cannabigerol (CBG) effectively reduced anxiety in a clinical trial without the intoxication typically associated with whole plant cannabis.

31 Jul 2024

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population.

30 Jul 2024

Study finds 3% of adolescents use CBD for health reasons

Since cannabidiol (CBD), the non-intoxicating component of cannabis, was legalized in the United States by the 2018 Farm Bill, products containing the compound have flooded the consumer health sector.

22 May 2024

Study reveals perceived risk of weekly cannabis use among women of childbearing age with disabilities

A growing number of states and territories in the United States have legalized medical and recreational cannabis use.

7 May 2024

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

A review in Current Research in Food Science explores how bioactive compounds in coffee, tea, and cocoa combat obesity by inhibiting white adipogenesis and promoting brown adipogenesis and lipolysis.

22 Apr 2024

Salk scientists explain how CBN protects the brain against aging and neurodegeneration

One in every 10 individuals above the age of 65 develops an age-related neurological disorder like Alzheimer's or Parkinson's, yet treatment options remain sparse for this population.

17 Apr 2024

Study explores how cannabis use affects breast milk and lactation

Study reviews the impact of cannabis use during pregnancy and lactation, highlighting potential changes in breast milk composition and lactation due to cannabinoid effects.

3 Apr 2024

Study unveils how cannabis affects brain's feeding center

While it is well known that cannabis can cause the munchies, researchers have now revealed a mechanism in the brain that promotes appetite in a set of animal studies at Washington State University.

16 Jan 2024

Unlocking the appetite-stimulating secrets of cannabis through rodent brain studies

Study reveals that cannabinoid-1 receptor-expressing neurons in the mediobasal hypothalamus play a key role in the appetite-stimulating effects of inhaled cannabis in rodents, offering insights into potential treatments for anorexia.

2 Jan 2024