Cardiovascular Disease News and Research

Latest Cardiovascular Disease News and Research

Daily moderate drinking may decrease atherosclerosis

For the first time, new research shows that patterns of alcohol consumption - a drink or two every night, or several cocktails on Friday and Saturday nights only - may be more important in determining alcohol's influence on heart health than the total amount consumed.

8 Sep 2011

New surprising discovery on division of mitochondria within cells

A surprising new discovery by the University of Colorado Boulder and the University of California, Davis regarding the division of tiny "power plants" within cells known as mitochondria has implications for better understanding a wide variety of human diseases and conditions due to mitochondrial defects.

8 Sep 2011

APS sponsors 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels

The American Physiological Society is sponsoring the 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels, being held September 18-22 at the Asilomar Conference Grounds in Pacific Grove, Calif. This scientific conference explores the connection between fluid balance in the body and hypertension, a growing global health concern.

8 Sep 2011

Ardea Biosciences reports positive outcome from lesinurad End-of-Phase 2 meetings with FDA

Ardea Biosciences, Inc. announced that it has completed formal End-of-Phase 2 meetings with the U.S. Food and Drug Administration (FDA) and successfully reached agreement on the following key aspects of its proposed lesinurad Phase 3 development plan: the overall size and design of the planned Phase 3 clinical studies, the primary endpoints, the total safety database proposed for NDA filing, manufacturing plans for both drug substance and drug product, the preclinical toxicology program and the clinical pharmacology program.

7 Sep 2011

International researchers to assess role of pre-clinical animal models in drug discovery

The New York Academy of Sciences and the Global Medical Excellence Cluster (GMEC), in collaboration with Imperial College London and King's College London, will host a two-day scientific conference, "Animal Models and Their Value in Predicting Drug Efficacy and Toxicity," that will provide a forum to critically examine the role of pre-clinical animal models in drug discovery.

7 Sep 2011

Individuals with excess BMI more likely to develop type 2 diabetes

Obesity is a known risk factor for developing type 2 diabetes. But it hasn't been clear whether the "dose" of obesity—how much excess weight a person has, and for how long—affects the risk of diabetes.

7 Sep 2011

Cheap medicines could prevent huge number of deaths from heart attacks, strokes

A major new international study involving researchers from the Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital has revealed that aspirin, statins, beta blockers and ACE inhibitors are prescribed far too infrequently. They are cheap, preventive medicines that could prevent a huge number of deaths from heart attacks and strokes.

7 Sep 2011

Chocolate protects heart but stirs debate on intake

A new study shows that chocolates are beneficial for heart health. The study published in the British Medical Journal and presented at the European Cardiology Society's annual congress in Paris analyzed data from seven studies involving 114,009 adults, ages 25 to 93, and including information on their diets and occurrences of cardiovascular disease over periods from eight to 16 years.

6 Sep 2011

Australia’s Mesoblast receives nod to start first European trial of allogeneic stem cell treatment for heart attacks

Global regenerative medicine company, Mesoblast Limited, (ASX: MSB), today announced that it had received clearance from the European Medicines Agency (EMA) to begin a 225-patient multi-center Phase 2 clinical trial in Europe for its lead cardiovascular product Revascor™ in conjunction with angioplasty and stent procedures to prevent heart failure after a major heart attack. Revascor™ is an allogeneic, or “off-the-shelf”, adult stem cell product derived from Mesoblast's proprietary Mesenchymal Precursor Cell (MPC) platform technology which is being developed for use in a range of cardiovascular diseases including congestive heart failure, chronic angina, and heart attacks (acute myocardial infarction).

5 Sep 2011

Combination of resistance training, AT does not benefit cardiac patients

For patients undergoing rehabilitation following cardiac events, aerobic exercise training (AT) is widely recommended. Resistance training (RT) has also been shown to be beneficial because it enhances muscular strength and endurance, functional capacity and independence, and quality of life, while reducing disability.

3 Sep 2011

New research puts an unexpected twist on how mitochondria divide within cells

New research from the University of California, Davis, and the University of Colorado at Boulder puts an unexpected twist on how mitochondria, the energy-generating structures within cells, divide.

3 Sep 2011

PTC restructures collaboration with Genzyme

PTC Therapeutics, Inc. and Genzyme, a Sanofi company, announced today the restructuring of their collaboration. Under the original agreement, PTC held commercial rights for the U.S. and Canada and Genzyme held commercial rights in all other countries.

2 Sep 2011

NCD summit negotiations must get back on track to help millions worldwide

With negotiations over the outcomes for the U.N. High-level Meeting on Non-Communicable Diseases (NCDs) stalled, "[i]t is feared that sound proposals for clear goals and timelines to tackle these devastating diseases are being systematically deleted, diluted and downgraded by some U.N. Member States and urgent action is needed to put the negotiations back on track, when they recommence on September 1," Rob Moodie, chair of Global Health at the Nossal Institute of Global Health, writes in the Crikey health blog "Croakey."

2 Sep 2011

Dr. Reddy’s initiates DRL-17822 Phase II study in type II dyslipidemia

Dr. Reddy's Laboratories announced the initiation of dosing with DRL-17822 in patients with diagnosis of type II dyslipidemia. DRL-17822 is a selective, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP), for the treatment and/or prevention of dyslipidemia, atherosclerosis and associated cardiovascular disease.

2 Sep 2011

Medtronic initiates U.S. post-approval study of Endurant AAA Stent Graft System

Leading the development of endovascular aortic repair (EVAR), Medtronic, Inc. today announced the start of its U.S. post-approval study of the Endurant AAA Stent Graft System, a medical device used to treat abdominal aortic aneurysms.

From Medtronic 2 Sep 2011

Inadequate sleep linked to high blood pressure: Study

In the study, men with the lowest level of the deeper stages of slumber, known as slow-wave sleep, had an 80 percent higher chance of developing high blood pressure than men with the highest level of this restorative sleep. The link held regardless of other factors, such as obesity or how long the men slept.

31 Aug 2011

Patients with coronary artery disease more likely to have complications from orthopedic surgery

Thrombotic and bleeding events are complications that may occur after surgery. With the aging population in the western world, there are more patients undergoing orthopedic surgery than ever before. This makes understanding the risk of complications from orthopedic surgery exceedingly important. However, there is a lack of data investigating the incidence of thrombotic and bleeding complications in orthopedic surgery.

31 Aug 2011

Life Expectancy with Disability is worse in European women than men

European women live longer than men, because of both biological and behavioural advantages, but women's longer lives are not necessarily healthy lives. Studies commented on by Dr Vannuzzo at the ESC Congress 2011, show that due to increase in tobacco and alcohol consumption in women, the gender gap is decreasing.

30 Aug 2011

BIOTRONIK Home Monitoring reduces inappropriate shocks, improves ICD battery longevity

BIOTRONIK, a leading manufacturer of implantable cardiac devices and the pioneer of wireless remote monitoring technology, announced today the first presentation of results from the ECOST randomized controlled trial.

30 Aug 2011

Stent for Life Initiative aims to support implementation of primary PCI in the ESC countries

Primary PCI is the best reperfusion therapy for patients presenting with acute ST-elevation myocardial infarction. CJ Terkelsen and co-workers used the Western Denmark Heart Registry to describe the implementation of primary PCI in Denmark.

30 Aug 2011

Cardiovascular Disease News and Research

Latest Cardiovascular Disease News and Research

Daily moderate drinking may decrease atherosclerosis

New surprising discovery on division of mitochondria within cells

APS sponsors 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels

Ardea Biosciences reports positive outcome from lesinurad End-of-Phase 2 meetings with FDA

International researchers to assess role of pre-clinical animal models in drug discovery

Individuals with excess BMI more likely to develop type 2 diabetes

Cheap medicines could prevent huge number of deaths from heart attacks, strokes

Chocolate protects heart but stirs debate on intake

Australia’s Mesoblast receives nod to start first European trial of allogeneic stem cell treatment for heart attacks

Combination of resistance training, AT does not benefit cardiac patients

New research puts an unexpected twist on how mitochondria divide within cells

PTC restructures collaboration with Genzyme

NCD summit negotiations must get back on track to help millions worldwide

Dr. Reddy’s initiates DRL-17822 Phase II study in type II dyslipidemia

Medtronic initiates U.S. post-approval study of Endurant AAA Stent Graft System

Inadequate sleep linked to high blood pressure: Study

Patients with coronary artery disease more likely to have complications from orthopedic surgery

Life Expectancy with Disability is worse in European women than men

BIOTRONIK Home Monitoring reduces inappropriate shocks, improves ICD battery longevity

Stent for Life Initiative aims to support implementation of primary PCI in the ESC countries

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Cardiovascular Disease News and Research

Latest Cardiovascular Disease News and Research

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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