Chemotherapy News and Research

Latest Chemotherapy News and Research

New ASPIRE trial tests chemotherapy combination for advanced prostate cancer

The Alliance for Clinical Trials in Oncology has launched the ASPIRE trial-a large-scale, Phase III clinical study investigating whether adding chemotherapy to current standard treatments can extend survival for men living with advanced prostate cancer.

6 Oct 2025

DKMS advances blood cancer research with groundbreaking ASAP study

The selection of patients for allo-HSCT and the best approach to bridging patients to transplantation is continuously discussed by experts.

6 Oct 2025

Inflammatory responses may play a role in cancer-related fatigue

New research reveals that inflammatory responses may play a role in different types of fatigue experienced by many people with cancer.

6 Oct 2025

Innovative topical cream relieves chemotherapy-induced peripheral neuropathy

Most patients receiving chemotherapy with taxanes or platinum salts develop pain and loss of sensitivity in their hands and feet—a severe side effect that can interfere with proper treatment.

3 Oct 2025

Newly discovered mechanism helps leukemia cells to evade the immune system

A research team at Lund University in Sweden has discovered a mechanism that helps acute myeloid leukemia cells to evade the body's immune system.

3 Oct 2025

Deadly brain cancer erodes skull bone and alters immune marrow

Scientists at Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine have shown for the first time that glioblastoma-the deadliest form of brain cancer-affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body's immune response.

3 Oct 2025

Nuclear missile workers are contracting cancer. They blame the bases.

At a memorial service in 2022, veteran Air Force Capt. Monte Watts bumped into a fellow former Minuteman III nuclear missile operator, who told him that she had non-Hodgkin lymphoma.

3 Oct 2025

Boosting the immune system to prevent cancer recurrence and improve survival

In experiments with mouse models of breast, pancreatic, and muscle cancers, researchers at Johns Hopkins All Children's Hospital report new evidence that a novel means of boosting the natural immune system prevents cancer recurrence and improves survival.

30 Sep 2025

Discovery of EUDAL reveals new mechanism behind chemotherapy resistance in oral cancer

Oral cancer is one of the most common head and neck cancers worldwide, with hundreds of thousands of new cases diagnosed every year. Despite advances in surgery, radiotherapy, and chemotherapy, survival rates remain poor.

30 Sep 2025

Tissue-mimicking hydrogels drive cell reprogramming via matrix remodeling

The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, which are closely associated with various diseases including neurodegenerative diseases and cancers.

30 Sep 2025

Post-operative radiation therapy reduces pelvic relapse in high-risk bladder cancer

Radiation therapy could be an underused tool to reduce pelvic relapse risk for patients with locally advanced, muscle-invasive bladder cancer, according to results of a new phase III randomized trial.

29 Sep 2025

Proton therapy and IMRT show similar outcomes in head and neck cancer trial

A new phase III clinical trial finds that intensity-modulated radiation therapy (IMRT) and proton beam therapy resulted in similar quality-of-life outcomes and low rates of side effects for people with locally advanced oropharyngeal cancer.

29 Sep 2025

Genetic variant linked to liver injury after chemotherapy in colorectal cancer patients

A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients with colorectal cancer that has spread to the liver experience more severe liver damage after chemotherapy.

29 Sep 2025

Small molecule AVJ16 shows promise in targeting lung cancer growth

Researchers have discovered a promising new approach to lung cancer treatment. A small molecule called AVJ16 selectively blocks the cancer-driving protein IGF2BP1, halting tumor growth in preclinical studies and killing cancer cells in patient-derived models—while leaving healthy cells unharmed.

29 Sep 2025

AI tool accurately distinguishes between glioblastoma and primary central nervous system lymphoma

A Harvard Medical School–led research team has developed an AI tool that can reliably tell apart two look-alike cancers found in the brain but with different origins, behaviors, and treatments.

29 Sep 2025

Novel treatment disrupts tumor immunosuppression in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%.

26 Sep 2025

Off-label drug helps one boy with autism speak, parents say. But experts want more data.

Caroline Connor's concerns about her son's development began around his 1st birthday, when she noticed he wasn't talking or using any words. Their pediatrician didn't seem worried, but the speech delay persisted. At 2½, Mason was diagnosed with autism.

26 Sep 2025