Chemotherapy News and Research

Latest Chemotherapy News and Research

Chemotherapy before surgery appears better than surgery alone for nonsmall cell lung cancer

Combining pre-operative chemotherapy and surgery increases the average chance of survival at five years by approximately 6% compared with surgery alone.

18 Jul 2007

Protein km23 - potential target for ovarian cancer treatment

A traffic cop protein in the cell may have an even more important role: transporting a messenger protein that tells components in the nucleus to stop cell growth.

17 Jul 2007

Researchers identify new combination therapy that promotes cancer cell death

Researchers at the University of Pennsylvania School of Medicine identified a combination therapy as a way to sensitize resistant human cancer cells to a treatment currently being tested in clinical trials They propose that the therapy may help to selectively eliminate cancer cells while leaving healthy cells intact, providing a cancer treatment with fewer side effects.

17 Jul 2007

New hope for childhood cancer sufferers

Scientists investigating drug therapies for children with Acute Lymphoblastic Leukaemia (ALL) have presented new data demonstrating for the very first time that a small molecule called ABT-737 can increase the effectiveness of standard therapies.

17 Jul 2007

Sequential and combination chemotherapy equally effective in treating advanced colorectal cancer

Many patients with incurable advanced colorectal cancer could be offered a more gentle treatment strategy starting with a single chemotherapy drug, as an alternative to current standard initial combination chemotherapy, without compromising their survival.

16 Jul 2007

Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer

The number of lymph nodes that contain evidence of cancer is the best predictor of the effectiveness of adding chemotherapy and radiation to a treatment plan prior to surgery in individuals with oesophageal cancer, according to a study published last month in the Annals of Surgery.

16 Jul 2007

Co-operation between GSF and clinic improves outlook for sarcoma patients

Hyperthermia, combined with chemotherapy, improves the chances of healing and survival of patients with low-lying, soft tissue sarcomas. At the Annual General Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, the GSF scientist Prof. Dr Rolf D.

16 Jul 2007

Scientists develop largest ever series of human breasts cancers grafted into mice

At the Institut Curie, Inserm researchers and physicians have established the largest ever panel of human breast cancer xenografts in animal models.

13 Jul 2007

St. Jude study holds promise for improving neuroblastoma treatment

A treatment for neuroblastoma that lands a one-two punch works best when the second punch is timed to take maximum advantage of the first one, according to results of studies at St. Jude Children's Research Hospital.

12 Jul 2007

Chemically-modified mitochondrial toxin could lead to a new molecularly-targeted chemo drug

A chemically-modified version of a mitochondrial toxin long used to control species of invasive fish in lakes has been found to selectively inhibit two "survival proteins" in cancer cells.

12 Jul 2007

Chemotherapy may benefit all women with a BRCA1 mutation

Breast cancer patients who possess one of the so-called "breast cancer" or BRCA genetic mutations do not have a higher risk of dying than patients with no BRCA mutations, according to a detailed study by researchers at the Technion-Israel Institute of Technology and the University of Toronto.

12 Jul 2007

New use for a cell toxin found to inhibit survival proteins in cancer cells

A chemically-modified version of a mitochondrial toxin long used to control species of invasive fish in lakes has been found to selectively inhibit two "survival proteins" in cancer cells.

11 Jul 2007

Potential role of milk thistle as an anticancer agent

Milk thistle extract, an herbal remedy since the times of the ancient Greeks and Romans, is today one of the most popular herbal supplements, with U.S. retail sales of nearly nine million dollars.

11 Jul 2007

Uncooked fish linked with liver cancer in Asia

An age old preference for eating uncooked fish dishes like koi-pla puts people in SE Asia at risk of ingesting trematodes that can cause a type of liver cancer called cholangiocarcinoma (cancer of the bile ducts), say researchers in this week's PLoS Medicine.

10 Jul 2007

Modified herpes virus - a killer of cancer cells

Scientists have developed a virus specifically designed to target cancer tissue while not affecting normal healthy tissue.

9 Jul 2007

Should soft tissue sarcomas be treated at high volume centres?

Soft tissue sarcomas -rare tumours of the connective tissue- should be treated at the few centres which see most cases, in order to give patients the best chance of good outcomes, concludes an analysis of sarcoma management in Florida, published in the Annals of Surgery last month.

9 Jul 2007

Abiraterone reduces levels of prostate specific antigen

For prostate cancer patients whose tumors have continued to grow despite medical or surgical castration, a new drug candidate that inhibits production of male hormones anywhere in the body is showing promise in early trials.

9 Jul 2007

Modified herpes simplex virus shows promise in early clinical trial

A virus that has been specifically designed by scientists to be safe to normal tissue but deadly to cancer is showing early promise in a preliminary study, researchers said at the ESMO Conference Lugano (ECLU), Switzerland.

9 Jul 2007

Trastuzumab and chemo improves survival in women with operable HER-2 positive breast cancer

A recent meta-analysis of five major breast cancer trials has confirmed that combination treatment with the antibody trastuzumab and chemotherapy improves survival in women with operable HER-2 positive breast cancer.

9 Jul 2007

OncoLife web-based cancer survivorhip care plan

A team of cancer specialists from OncoLink.org, the award-winning cancer Web-based resource of the Abramson Cancer Center of the University of Pennsylvania, has launched OncoLife, the first and only individualized plan-of-care based on the national Institute of Medicine's recommendations for adult cancer survivors.

4 Jul 2007