Cholera News and Research

Latest Cholera News and Research

Researchers develop early warning systems for preventing epidemics

The environment has an impact on our health. Preventing epidemics relies on activating the right counter-measures, and scientists are now trying to find out how better use of forecasting can help.

24 Feb 2014

PaxVax reports interim data from Phase 3 cholera challenge study of PXVX0200

PaxVax Inc, which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced interim data from a Phase 3 cholera challenge study of its single-dose oral cholera vaccine candidate, PXVX0200 (also known as CVD 103-HgR). Trial investigators compared the rate of diarrhea in participants vaccinated with PXVX0200 to the rate in participants who had received placebo.

10 Jan 2014

Transport of bacterial substrates through injectisome observed almost in real time

When attacking body cells, bacteria, such as salmonellae or Yersinia (plague pathogens), inject specific bacterial proteins through hollow, syringe-like structures - called injectisomes - into the host cells. These substances reprogram the cells and can thus overcome their defense. From then on, they can infiltrate the cells unhindered in large numbers, and trigger diseases such as typhus, plague, or cholera.

13 Dec 2013

Penn researchers identify protein that could clear Alzheimer's plaques

The body is structured to ensure that any invading organisms have a tough time reaching the brain, an organ obviously critical to survival. Known as the blood-brain barrier, cells that line the brain and spinal cord are tightly packed, making it difficult for anything besides very small molecules to cross from the bloodstream into the central nervous system. While beneficial, this blockade also stands in the way of delivering drugs intended to treat neurological disorders, such as Alzheimer's.

9 Dec 2013

URC leads new project to improve people's health status in Haiti

University Research Co., LLC is leading a new project in Haiti, a country with complex public health issues, including decentralization, HIV/AIDS, and cholera, to improve the population's health status.

22 Oct 2013

Evidence shows vaccination pilot campaigns highly successful during 2010 cholera epidemic

The deadly cholera epidemic that rocked earthquake-shattered Haiti in 2010, claiming 8,000 lives and counting, has rallied the public health community to seek water and sewer improvements that, combined with vaccination, could prevent some 89,000 future cholera infections.

11 Oct 2013

University of Maryland receives renewed NIH funding for vaccine research

The University of Maryland School of Medicine's Center for Vaccine Development (CVD) has successfully competed for and received a renewed contract to conduct basic research and clinical studies of vaccines, diagnostics, and therapeutics. Support for this work to combat existing and emerging infectious diseases is provided by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

27 Sep 2013

Group Health helps protect public from infectious diseases through nationwide network

A nationwide group of institutions that conducts clinical trials of promising candidate vaccines and therapies for infectious diseases, known as the Vaccine and Treatment Evaluation Units (VTEUs), has been awarded nine contracts to strengthen and broaden the scope of its research. Group Health Research Institute is one of these institutions.

27 Sep 2013

MIT engineers develop nanoparticles that deliver cancer vaccines to lungs

Many viruses and bacteria infect humans through mucosal surfaces, such as those in the lungs, gastrointestinal tract and reproductive tract. To help fight these pathogens, scientists are working on vaccines that can establish a front line of defense at mucosal surfaces.

26 Sep 2013

Researchers discover how Yersinia immobilizes immune system to spread within organs

Researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have identified how one type of bacteria, Yersinia, immobilizes the immune system in order to grow in the organs of mice. To do so, the researchers extended the use of a technique and suggest that it could be used to study other bacteria that use the same or similar means of infection.

17 Sep 2013

Annual treated wastewater in North America roughly equals volume of Niagara Falls; less than 4% is reused

Amid growing competition for freshwater from industry and cities, coupled with a rising world shortage of potash, nitrogen and phosphorus, an international study predicts a rapid increase in the use of treated wastewater for farming and other purposes worldwide.

7 Sep 2013

PaxVax commences phase 3 clinical trial for single-dose oral cholera vaccine candidate

PaxVax Inc, which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced that it has commenced its Phase 3 clinical trial program for its single-dose oral cholera vaccine candidate, PXVX0200 (also known as CVD 103-HgR). Approximately 3,000 participants will be enrolled in this pivotal program, which is comprised of cholera challenge, safety, and immunogenicity studies.

7 Sep 2013

New techniques for predicting severity of seasonal cholera epidemics

In two recently published papers, Tufts University School of Engineering researchers have established new techniques for predicting the severity of seasonal cholera epidemics months before they occur and with a greater degree of accuracy than other methods based on remote satellite imaging.

16 Aug 2013

Study highlights challenges of predicting disease outcomes in warming world

Climate change is already affecting the spread of infectious diseases--and human health and biodiversity worldwide--according to disease ecologists reporting research results in this week's issue of the journal Science.

13 Aug 2013

Researchers uncover evidence that genetic changes play role in resistance to deadly disease

Researchers have long understood that genetics can play a role in how susceptible people are to contracting cholera, but a team of Harvard scientists is now uncovering evidence of genetic changes that might also help protect some people from contracting the deadly disease.

20 Jul 2013

Study identifies genomic regions associated with cholera susceptibility

An international research team has used a novel approach to identify genetic factors that appear to influence susceptibility to cholera. The findings by investigators from Massachusetts General Hospital (MGH), the Broad Institute and the International Center for Diarrh-al Disease Research, Bangladesh (ICDDR,B) indicate the importance of pathways involved in regulating water loss in intestinal cells and of the innate immune system in the body's response to the bacteria that causes cholera, which affects from 3 to 5 million people each year and causes more than 100,000 deaths.

4 Jul 2013

Researchers discover role of TonB bacterial protein that causes various diseases

A Kansas State University-led study has discovered the role of a protein in bacteria that cause a wide variety of diseases, including typhoid fever, plague, meningitis and dysentery. The results may lead to new and improved antibiotics for humans and animals.

2 Jul 2013

Study reveals strain of V. cholerae in Haiti cholera outbreak originated from single source

The strain of cholera that has sickened thousands in Haiti came from a single source and was not repeatedly introduced to the island over the past three years as some have thought, according to a new study published in mBio-, the online open-access journal of the American Society for Microbiology.

2 Jul 2013

Study explores potential of satellite remote sensing data on the occurrence of cholera

Cholera remains one of the most prevalent water-related infections in many tropical regions of the world, specifically coastal areas of South Asia, Africa, and Latin America. We now know how to treat cholera patients, and hence mortality for cholera has considerably decreased in several parts of the globe.

4 Jun 2013

Experts from ProfNet are available to discuss hurricane preparedness and response

With hurricane season on its way, here are experts from the ProfNet network that are available to discuss hurricane preparedness and response for consumers and businesses. If you are interested in interviewing any of the experts, please contact them via the contact information at the end of the listing.

1 Jun 2013

Cholera News and Research

Latest Cholera News and Research

Researchers develop early warning systems for preventing epidemics

PaxVax reports interim data from Phase 3 cholera challenge study of PXVX0200

Transport of bacterial substrates through injectisome observed almost in real time

Penn researchers identify protein that could clear Alzheimer's plaques

URC leads new project to improve people's health status in Haiti

Evidence shows vaccination pilot campaigns highly successful during 2010 cholera epidemic

University of Maryland receives renewed NIH funding for vaccine research

Group Health helps protect public from infectious diseases through nationwide network

MIT engineers develop nanoparticles that deliver cancer vaccines to lungs

Researchers discover how Yersinia immobilizes immune system to spread within organs

Annual treated wastewater in North America roughly equals volume of Niagara Falls; less than 4% is reused

PaxVax commences phase 3 clinical trial for single-dose oral cholera vaccine candidate

New techniques for predicting severity of seasonal cholera epidemics

Study highlights challenges of predicting disease outcomes in warming world

Researchers uncover evidence that genetic changes play role in resistance to deadly disease

Study identifies genomic regions associated with cholera susceptibility

Researchers discover role of TonB bacterial protein that causes various diseases

Study reveals strain of V. cholerae in Haiti cholera outbreak originated from single source

Study explores potential of satellite remote sensing data on the occurrence of cholera

Experts from ProfNet are available to discuss hurricane preparedness and response

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Cholera News and Research

Latest Cholera News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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