Chromosome News and Research

Latest Chromosome News and Research

Scientists identify link between rare mutations in RINT1 gene and early onset breast cancer risk

An international team of scientists has identified an association between heritable, rare mutations in the RINT1 gene and increased risk of early onset breast cancer, according to research reported today (Oct. 24) at the American Society of Human Genetics 2013 annual meeting in Boston.

25 Oct 2013

Study identifies gene that raises risk for colorectal cancer from eating red or processed meat

A common genetic variant that affects 1 in 3 people significantly increases the risk of colorectal cancer from the consumption of red meat and processed meat, according to a study presented today at the annual American Society of Human Genetics 2013 meeting, the largest gathering of human geneticists in the world.

25 Oct 2013

U of T researchers develop method to screen human stem cells

University of Toronto researchers have developed a method that can rapidly screen human stem cells and better control what they will turn into. The technology could have potential use in regenerative medicine and drug development. Findings are published in this week's issue of the journal Nature Methods.

23 Oct 2013

Scientist receives NIH New Innovator Award to design innovative approaches for cancer treatment

Derek Taylor, PhD, a member of the Case Western Reserve School of Medicine, has been awarded the prestigious New Innovator Award by the National Institutes of Health (NIH).

22 Oct 2013

Study finds inherited GATA3 gene variation increases risk of developing pediatric leukemia

Research led by St. Jude Children's Research Hospital scientists has linked an inherited gene variation to a nearly four-fold increased risk of developing a pediatric acute lymphoblastic leukemia (ALL) subtype that is associated with a poor outcome.

21 Oct 2013

Study: Pds5 proteins modulate behavior of cohesins to ensure proper division of cells

Cohesins are protein complexes that join the two copies of each chromosome-called sister chromatids-to ensure that they are shared fairly between the daughter cells during cell division. In this way, each daughter cell receives exactly the same genetic information from the parent cell.

19 Oct 2013

Research: Hypermutation in cancer is more frequent in inactive X chromosome

Every case of cancer originates from changes in a person's genetic material (mutations). These usually occur as "somatic mutations" in individual cells during an individual's lifetime, rather than being inherited from a person's parents.

19 Oct 2013

Ariad Ends Phase III Leukemia Drug Trial

...

18 Oct 2013

ARIAD discontinues Phase 3 EPIC trial of Iclusig in patients with chronic myeloid leukemia

ARIAD Pharmaceuticals, Inc. today announced that it is discontinuing the Phase 3 EPIC (Evaluation of Ponatinib versus Imatinib in Chronic Myeloid Leukemia) trial of Iclusig (ponatinib) in patients with newly diagnosed chronic myeloid leukemia.

18 Oct 2013

National survey reveals misconceptions about miscarriage

The majority of Americans inaccurately believe miscarriage is rare and misunderstand its causes, creating an often isolating and guilt-ridden experience for those who experience it. These are the findings in the first-ever national survey to assess attitudes and perceptions towards miscarriage, which was conducted by researchers at Montefiore Medical Center and the Albert Einstein College of Medicine of Yeshiva University.

18 Oct 2013

Researchers identify genetic variants associated with Barrett's and esophageal cancer

An international consortium co-led by researchers at Fred Hutchinson Cancer Research Center and the QIMR Berghofer Medical Research Institute in Australia has identified four genetic variants associated with an increased risk of esophageal cancer and its precursor, a condition called Barrett's esophagus.

14 Oct 2013

CNIO researchers perform first exome sequencing for non-infiltrating bladder cancer

Bladder cancer represents a serious public health problem in many countries, especially in Spain, where 11,200 new cases are recorded every year, one of the highest rates in the world. The majority of these tumours have a good prognosis -- 70-80% five-year survival after diagnosis -- and they do not infiltrate the bladder muscle at the time of diagnosis -- in around 80% of cases.

14 Oct 2013

Research findings may lead to new ways to combat cancer

The way cells divide to form new cells - to support growth, to repair damaged tissues, or simply to maintain our healthy adult functioning - is controlled in previously unsuspected ways UC San Francisco researchers have discovered.

12 Oct 2013

Research findings may lead to potential treatments for inherited diseases

New research from the University of California, Davis, shows that the tiny proportion of a cell's DNA that is located outside the cell nucleus has a disproportionately large effect on a cell's metabolism.

12 Oct 2013

People who lower stress levels through meditation, yoga have longer telomeres

Targeting telomeres, the protective caps at the end of all chromosomes that are critical to healthy cell function, T.A. Sciences' products activate an enzyme that can slow down and possibly reverse age- and lifestyle-related telomere shortening. Short telomeres can cause mutations and degradations to chromosomes leading to loss of cell functionality. Its inaugural product, TA-65 is the only proven product specifically focused on the telomerase activation market.

12 Oct 2013

Research delves deeply into genomics of glioblastoma multiforme cases to better target disease

When The Cancer Genome Atlas launched its massively collaborative approach to organ-by-organ genomic analysis of cancers, the brain had both the benefit, and the challenge, of going first.

11 Oct 2013

IVF and chromosome testing: an interview with Dr. Santiago Munné

The Society for Assisted Reproductive Technology (SART) releases every year a report on pregnancy rates by maternal age. The last one shows a decline on implantation rates per embryo from 36% in young women, to 27.3% in women 35-37, 17.5% in 38-40, and less than 10% above 40 years of age.

10 Oct 2013

Mechanism preserving genome integrity help develop new therapies against DiGeorge syndrome

An international team of scientists-including researchers at GENYO, the Centre for Genomics and Oncological Research (Pfizer-University of Granada- Andalusian Regional Government)-has described a molecular mechanism that facilitates the defence of the human genome against "bombarding" by mobile DNA sequences.

10 Oct 2013

Thwarting Greatwall May Trigger Mitotic Collapse And Suppress Tumor Development

...

9 Oct 2013

ARIAD announces changes in Iclusig product labeling to reflect updated safety information

ARIAD Pharmaceuticals, Inc. today announced results of its review of updated clinical data from the pivotal PACE trial of Iclusig® (ponatinib) and actions that it is taking following consultations with the U.S. Food and Drug Administration (FDA).

9 Oct 2013

Chromosome News and Research

Latest Chromosome News and Research

Scientists identify link between rare mutations in RINT1 gene and early onset breast cancer risk

Study identifies gene that raises risk for colorectal cancer from eating red or processed meat

U of T researchers develop method to screen human stem cells

Scientist receives NIH New Innovator Award to design innovative approaches for cancer treatment

Study finds inherited GATA3 gene variation increases risk of developing pediatric leukemia

Study: Pds5 proteins modulate behavior of cohesins to ensure proper division of cells

Research: Hypermutation in cancer is more frequent in inactive X chromosome

Ariad Ends Phase III Leukemia Drug Trial

ARIAD discontinues Phase 3 EPIC trial of Iclusig in patients with chronic myeloid leukemia

National survey reveals misconceptions about miscarriage

Researchers identify genetic variants associated with Barrett's and esophageal cancer

CNIO researchers perform first exome sequencing for non-infiltrating bladder cancer

Research findings may lead to new ways to combat cancer

Research findings may lead to potential treatments for inherited diseases

People who lower stress levels through meditation, yoga have longer telomeres

Research delves deeply into genomics of glioblastoma multiforme cases to better target disease

IVF and chromosome testing: an interview with Dr. Santiago Munné

Mechanism preserving genome integrity help develop new therapies against DiGeorge syndrome

Thwarting Greatwall May Trigger Mitotic Collapse And Suppress Tumor Development

ARIAD announces changes in Iclusig product labeling to reflect updated safety information

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Chromosome News and Research

Latest Chromosome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Newsletters you may be interested in