Chromosome News and Research

Latest Chromosome News and Research

C. albicans capable of sexual reproduction

Like many fungi and one-celled organisms, Candida albicans, a normally harmless microbe that can turn deadly, has long been thought to reproduce without sexual mating. But a new study by Professor Judith Berman and colleagues at the University of Minnesota and Tel Aviv University shows that C. albicans is capable of sexual reproduction.

31 Jan 2013

Researchers identify mechanism by which vancomycin resistance spreads between bacteria

Worldwide, many strains of the bacterium Staphyloccocus aureus, commonly known as staph infections, are already resistant to all antibiotics except vancomycin. But as bacteria are becoming resistant to this once powerful antidote, S. aureus has moved one step closer to becoming an unstoppable killer.

31 Jan 2013

Bipolar pedigree endophenotypes found

Researchers have found cognitive endophenotypes in a single extended family showing linkage of bipolar disorder to a risk locus on chromosome 4.

30 Jan 2013

Telomerase gene mutation immortalizes deadly skin cancer

About ten percent of all cases of malignant melanoma are familial cases. The genome of affected families tells scientists a lot about how the disease develops. Prof. Dr. Rajiv Kumar of the German Cancer Research Center together with Prof. Dr. Dirk Schadendorf from Essen University Hospital studied a family where 14 family members were affected by malignant melanoma.

28 Jan 2013

Novartis receives FDA approval for Ph+ acute lymphoblastic leukemia

The U.S. Food and Drug Administration today approved a new use of Gleevec (imatinib) to treat children newly diagnosed with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL).

27 Jan 2013

Genome sequencing data gives important clues on cancer

Genome sequencing data once regarded as junk is now being used to gain important clues to help understand disease.

25 Jan 2013

Mice with reduced caloric intake accumulate longer telomeres

One of the indicators of a cell's health is the state of its DNA and containers-the chromosomes-so when these fuse together or suffer anomalies, they can become the source of illnesses like cancer and/or ageing processes.

23 Jan 2013

Brown biology professor named Pew's Scholar of the Month

Biologist Erica Larschan, Ph.D., was named by The Pew Charitable Trusts as the "Scholar of the Month," for her innovative findings on chromosomal activity in fruit flies.

22 Jan 2013

BRCA1-deficient cancer cells take advantage of DNA repair mechanism

Cancer cells are resourceful survivors with plenty of tricks for staying alive. Researchers have uncovered one of these stratagems, showing how cells lacking the tumor suppressor BRCA1 can resume one form of DNA repair, sparing themselves from stagnation or death. The study appears in the January 21st issue of The Journal of Cell Biology.

22 Jan 2013

New details about molecular surveillance system that helps detect and correct errors in cell division

Studies led by cell biologist Thomas Maresca at the University of Massachusetts Amherst are revealing new details about a molecular surveillance system that helps detect and correct errors in cell division that can lead to cell death or human diseases. Findings are reported in the current issue of the Journal of Cell Biology.

21 Jan 2013

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.

21 Jan 2013

EMA adopts positive opinion for Pfizer’s bosutinib conditional approval in the EU

Pfizer Inc. announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion regarding the conditional marketing authorization of bosutinib in the European Union for the treatment of adult patients with chronic phase (CP), accelerated phase (AP), and blast phase (BP) Philadelphia chromosome positive chronic myelogenous leukemia previously treated with one or more tyrosine kinase inhibitor(s) (TKIs) and for whom imatinib, nilotinib and dasatinib are not considered appropriate treatment options.

19 Jan 2013

Miscarriage and molecular signals: an interview with Prof Brosens and Prof Quenby

Miscarriage is defined as the spontaneous loss of pregnancy before the baby reaches viability. Besides the physical trauma, miscarriage causes considerable anxiety, stress, and depression.

17 Jan 2013

U-M researchers to develop disorders of sex development decision-making tools for parents

When a child is born with a disorder of sex development, decisions regarding gender assignment and genital surgery are often made quickly and under pressure.

17 Jan 2013

Stem cell transplantation prevents decrease in heart function associated with DMD

Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD.

16 Jan 2013

Researchers uncover genetic causes of von Willebrand disease

In 2006, the lab of Dr. David Ginsburg at the Life Sciences Institute put a call out for siblings attending the University of Michigan to donate blood for a study of blood-clotting disorders.

10 Jan 2013

Susceptibility genes for bovine digital dermatitis found

Researchers have identified genetic variants that influence susceptibility to bovine digital dermatitis, an infectious condition that causes lameness of the hindfoot.

9 Jan 2013

Researchers identify four new genetic regions associated with Behcet's disease

Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road.

7 Jan 2013

Manipulating T cells with iPSC techniques could help develop effective immune therapies

The human body contains immune cells programmed to fight cancer and viral infections, but they often have short lifespans and are not numerous enough to overcome attacks by particularly aggressive malignancies or invasions.

4 Jan 2013

PSCA gene’s rs2294008 variant on T nucleotide may increase risk of bladder cancer

Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic and prostate tumors, according to research at the National Institutes of Health.

4 Jan 2013

Chromosome News and Research

Latest Chromosome News and Research

C. albicans capable of sexual reproduction

Researchers identify mechanism by which vancomycin resistance spreads between bacteria

Bipolar pedigree endophenotypes found

Telomerase gene mutation immortalizes deadly skin cancer

Novartis receives FDA approval for Ph+ acute lymphoblastic leukemia

Genome sequencing data gives important clues on cancer

Mice with reduced caloric intake accumulate longer telomeres

Brown biology professor named Pew's Scholar of the Month

BRCA1-deficient cancer cells take advantage of DNA repair mechanism

New details about molecular surveillance system that helps detect and correct errors in cell division

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

EMA adopts positive opinion for Pfizer’s bosutinib conditional approval in the EU

Miscarriage and molecular signals: an interview with Prof Brosens and Prof Quenby

U-M researchers to develop disorders of sex development decision-making tools for parents

Stem cell transplantation prevents decrease in heart function associated with DMD

Researchers uncover genetic causes of von Willebrand disease

Susceptibility genes for bovine digital dermatitis found

Researchers identify four new genetic regions associated with Behcet's disease

Manipulating T cells with iPSC techniques could help develop effective immune therapies

PSCA gene’s rs2294008 variant on T nucleotide may increase risk of bladder cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Chromosome News and Research

Latest Chromosome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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