Chromosome News and Research

Latest Chromosome News and Research

Possible biomarker for colon cancer in people 50 and under

An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease.

28 Oct 2007

Discovery of a key cell-signaling pathway

University of Alabama at Birmingham (UAB) researchers have discovered a key cell-signaling pathway that regulates cell progression and switches on front-to-back body patterning in tadpoles.

28 Oct 2007

Test gives insight into prognosis in patients with plasma cell malignancies

A new Mayo Clinic study due to be presented at the annual meeting of the American Society of Human Genetics in San Diego this week shows that a chromosome test called “FISH” is better than conventional methods in identifying chromosomal genetic abnormalities associated with plasma cell malignancies.

24 Oct 2007

Researchers find crucial signal that switches on eye development

Researchers at the University of Warwick, funded by Wellcome Trust, have uncovered a crucial signal that switches on eye development.

24 Oct 2007

Potent inhibitor of Kinesin CENP-E demonstrates tumor cell inhibition

A first-in-class, targeted investigational therapy specifically designed to inhibit a single protein that functions only during cell division shows potent activity in a broad range of cancer cell lines, say researchers from GlaxoSmithKline.

24 Oct 2007

Experimental cancer pharmaceuticals under trial

A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro: Abstract A 111.

24 Oct 2007

Advances in drug screening

With the discovery of suitable molecular targets - cellular molecules along pathways crucial for sustaining the life of cancer cells - comes the perplexing dilemma of where to find the next therapeutics that will bind to and disable those targets.

23 Oct 2007

Researchers discover genes linking stress, high blood pressure, alcoholism and tobacco addiction

A team led by a Heart and Stroke Foundation researcher has uncovered a series of genes linking mental stress, high blood pressure, alcoholism and tobacco addiction.

22 Oct 2007

Syngenta licenses chromatin gene stacking technology

Syngenta Biotechnology Inc. has announced that it has entered into a research and commercial license agreement for Chromatin's proprietary gene stacking technology.

22 Oct 2007

Chromatin licenses gene stacking technology to Syngenta Biotechnology

Chromatin Inc. has announced that it has entered into a research and commercial license agreement with Syngenta Biotechnology Inc. for Chromatin's proprietary gene stacking technology.

22 Oct 2007

New explanation for evolutionary changes in genetic sex-determination systems

In animals with separate sexes, embryos commit to becoming male or female at an early stage.

22 Oct 2007

Transgenics sped up

A new method of constructing artificial plant chromosomes from small rings of naturally occurring plant DNA can be used to transport multiple genes at once into embryonic plants where they are expressed, duplicated as plant cells divide, and passed on to the next generation -- a long-term goal for those interested in improving agricultural productivity.

19 Oct 2007

Oral medication restores missing protein in boys with muscular dystrophy

PTC124, an oral medication that changes the way muscle cells interpret genetic information, holds promise as a treatment for some patients with Duchenne muscular dystrophy (DMD), the Muscular Dystrophy Association ( http://www.mda.org/ ) announced today.

19 Oct 2007