Chromosome News and Research

Latest Chromosome News and Research

Brca2 gene prevents medulloblastoma

Investigators at St. Jude Children's Research Hospital have gained some of the first major insights into how certain genes known to prevent cancer also guide the normal development of the nervous system before birth and during infancy by repairing DNA damage.

22 May 2007

Chemotherapy drug temozolomide shrinks brain tumors

Cancerous brain tumors appear to respond favorably to the drug temozolomide when used as primary chemotherapy after surgery, and the treatment appears to work best in people missing a certain gene, according to a study published in the May 22, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.

22 May 2007

Patients with myelodysplastic syndromes treated with Revlimid are living longer and remaining transfusion independent

New updated results from a pivotal Phase II trial evaluating Revlimid in patients with an incurable blood cancer known as myelodysplastic syndromes (MDS) were presented by Dr. Alan List, from the H. Lee Moffitt Cancer Center & Research Institute, at the 9th International Symposium on MDS currently taking place in Florence, Italy.

18 May 2007

First draft of the genome sequence of Aedes aegypti mosquito

Developing new strategies to prevent and control yellow fever and dengue fever has become more possible with the completion of the first draft of the genome sequence of Aedes aegypti mosquito by scientists led by Vishvanath Nene at The Institute for Genomic Research (TIGR) and David Severson at the University of Notre Dame.

18 May 2007

Some NSAIDs may be better suited to treating cancer

Until recently, nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and celecoxib (sold as Celebrex), were being hailed as promising cancer prevention drugs.

18 May 2007

Testosterone gel helps men multiple sclerosis

Close on the heels of a large-scale clinical trial just underway to confirm that the female hormone estriol combats the effects of multiple sclerosis (MS) in women, a just completed pilot study at UCLA now shows promise for the use of testosterone to combat its effects in men.

16 May 2007

Researchers identify genetic markers associated with breast cancer tumor grade and lymph node metastases

Researchers have identified genetic markers on several chromosomes in the tissue surrounding tumor cells that are associated with breast cancer tumor grade and the presence of lymph node metastases, according to a study in the May 16 issue of JAMA.

16 May 2007

Cells that cause Ewing's sarcoma identified

Inserm researchers at the Institut Curie have identified the cells that cause Ewing’s sarcoma.

16 May 2007

Engineered minichromosomes for medically useful proteins and metabolites

A team of scientists at the University of Missouri-Columbia has discovered a way to create engineered minichromosomes in maize and attach genes to those minichromosomes.

16 May 2007

Protein findings establish better understanding of tumor development

Peter Baumann, Ph.D., Assistant Investigator, and Nancy Bae, Ph.D., Postdoctoral Research Associate in the Baumann Lab, have published a paper offering insight into the way cells protect chromosome ends from misguided repair.

11 May 2007

New understanding of ubiquitylation

It turns out there's more than one way to skin a gene. New research from Rockefeller University suggests that two closely related DNA unpackaging mechanisms may not work the way scientists thought.

10 May 2007

Opossum DNA provides new insight into natural selection

Study of the DNA of a South American marsupial called the opossum has revealed that a gene's location influences whether or not it is likely to gather changes that could lead to disease.

10 May 2007

Genetic component to autism

Using an innovative statistical approach, a research team from Washington University School of Medicine in St. Louis and the University of California, Los Angeles, has identified two regions of DNA linked to autism.

10 May 2007

Cornell University establishes Center for Reproductive Genomics

Cornell University has established the Center for Reproductive Genomics, which will combine basic research in reproductive sciences on Cornell's Ithaca campus with one of the country's leading fertility clinics at Weill Cornell Medical College (WCMC) in New York City.

10 May 2007

Genetics of bipolar disorder

The likelihood of developing bipolar disorder depends in part on the combined, small effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself, a new study shows.

9 May 2007

New mapping technique will answer fundamental questions about chromosome structure

Researchers at the University of Illinois have developed a simple and economical technique for imaging and mapping fruit fly chromosomes.

8 May 2007

Six week baby sex test available on the internet

Prospective parents eager to know the sex of their unborn child can now buy a test on the internet which will tell them at just six weeks whether they are having a boy or a girl.

7 May 2007

New understanding of genetic mutation that contributes to autism

The investigators now know more about how the mutation causes problems with a specific gene and are testing for additional mutations of the same gene in other people with autism.

4 May 2007

There may be a real code to chromosomal organization

The identification of a cluster of essential genes on mouse chromosome 11 as well as similar clusters on the chromosomes of other organisms , including humans , buttresses the argument that there may be rules as to how genes are structured or laid out on chromosomes, said the Baylor College of Medicine senior author of a report that appears online in the Public Library of Science Genetics, an open-access publication.

4 May 2007

Scientists work out mechanism underlying asymmetric cell division in nematode worms

When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells.

4 May 2007