Chromosome News and Research

Latest Chromosome News and Research

Study sheds new light on children with a severe form of acute lymphoblastic leukemia

A new international study of children with a severe form of acute lymphoblastic leukemia (ALL) shows that certain chromosome losses can signal an especially poor response to therapy, but that other chromosome abnormalities have no effect on treatment survival.

5 May 2004

Developing smart drugs

Dana-Farber Cancer Institute Researchers, sensing an opening in the cancer battle, are mounting a quick thrust to flush out suspected molecular cancer triggers in tumor cells.

30 Apr 2004

Scientists have discovered a genetic cause of cleft lip and palate in mice

By watching mice “dance” and comparing the DNA of the dancers to their flat-footed siblings, scientists have discovered a genetic cause of cleft lip and palate in mice, a finding that is already being used to search for a similar genetic defect in humans.

29 Apr 2004

Transplanted bone-marrow cells could regenerate nerve cells in the brain

Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of neurodegenerative disorders such as Parkinson's disease.

29 Apr 2004

Mystery surrounding ageing, death and cancer is dispelled by new study

Scientists from Cancer Research UK and Breast Cancer Campaign have uncovered the first evidence of an entirely new system for holding the ravages of time at bay.

29 Apr 2004

Lou Gehrig’s disease gene discovered

A gene for a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) has been isolated in families in the United States, Belgium and Austria, the Muscular Dystrophy Association (MDA) announced today.

29 Apr 2004

Clinical trial of enzyme replacement therapy for the treatment of Gaucher disease

Transkaryotic Therapies, Inc. today announced that it has initiated a clinical trial to evaluate the safety and clinical activity of GA-GCB, its enzyme replacement therapy for the treatment of Gaucher disease.

26 Apr 2004

Discovery shows how single genetic mutation can cause complex disorders

Bardet-Biedl syndrome (BBS), characterized by obesity, learning disabilities and eye and kidney problems, is caused by genetic mutations in the BBS family of genes. Now, researchers who've long studied the condition have discovered that genetic mutations in one of those genes, called BBS4, lead to cell death by disrupting the cells' internal "highway" system.

25 Apr 2004

New techniques to search the yeast genome for genes that help keep copied chromosomes together

Johns Hopkins scientists have successfully used new techniques to search the yeast genome for genes that help keep copied chromosomes together, protecting the integrity of the organism's genetic material during cell division.

22 Apr 2004

Protein on the centrosome key to new strategies for stopping cancer growth

A Mayo Clinic discovery about a protein known as Dynamin-2 has thrown conventional wisdom for a loop. Finding the protein on the centrosome, a minute structure near a cell’s nucleus, may lead to new strategies for stopping cancer growth.

20 Apr 2004

New method that will revolutionize the search for genes

Medical researchers know that most common human diseases, such as hypertension and diabetes, have a large genetic component. Many genes, interacting with the environment, contribute to these diseases. For researchers, a major challenge is finding all the genes involved with a particular disease.

18 Apr 2004

New information on genetic shuffling before egg or sperm formation rewrites genetic theory

Key decisions in the genetic shuffling that occurs before eggs or sperm are formed are made earlier than thought, rewriting textbook genetics, according to recent papers from researchers at UC Davis, Harvard University and UC San Diego.

16 Apr 2004

Extensive gene traffic, the process of genes leaving and arriving on the chromosome

Researchers at the University of Chicago have discovered there is extensive gene “traffic”—the process of genes leaving and arriving on the chromosome—on the mammalian X chromosome. They also have overturned a conventional theory about how genes evolved on the sex chromosome.

16 Apr 2004

Scientists discover gene for Parkinson's disease

UCL scientists have discovered a new gene implicated in the early development of Parkinson's disease. In a study of families with early onset disease, Professor Nick Wood and colleagues at University College London's Institute of Neurology identified a novel gene which produces a malfunctioning protein that could pave the way for new treatments for Parkinson sufferers.

16 Apr 2004

Genetic mutation raises interesting questions about the evolution of the Y chromosome

The names and dates comprising a family tree contain branches that can extend backward centuries in time. People use these diagrams to discover their ancestral origin. Scientists use them to study the genealogical origins of entire species, tracing evolutionary history down to changes in a single gene.

14 Apr 2004

Autism gene discovered

Researchers at Mount Sinai School of Medicine are first to strongly link a specific gene with autism. While earlier studies have found rare genetic mutations in single families, a study published in the April issue of the American Journal of Psychiatry is the first to identify a gene that increases susceptibility to autism in a broad population.

14 Apr 2004

Surprises found In gene variation associated with schizophrenia

Approximately two percent of Caucasians have a gene segment variation that can cause a certain form of schizophrenia. Most people with the variation, known as a polymorphism, do not have the disease. A University of Iowa Health Care study reveals a good prognosis for people who do have this form of schizophrenia.

12 Apr 2004

Researchers isolate gene responsible for Chron's disease

Crohn's disease is an inflammatory bowel disease and its prevalence is increasing in industrialized nations. Existing treatments are considered unsatisfactory, often requiring recurring hospitalization and surgeries.

12 Apr 2004

Completion of the sequencing of human chromosome 19

The United States Department of Energy (DOE) Joint Genome Institute (JGI) and Stanford University report today the completion of the sequencing of human chromosome 19, the most gene-rich of all the human chromosomes. This achievement is described in the April 1, 2004 edition of the journal Nature.

7 Apr 2004

Launch of The Oxford Genetics Knowledge Park by Matt Ridley

The Oxford Genetics Knowledge Park is a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, and is one of six such Parks nationally, funded by the Departments of Health and Trade and Industry. The aim of the Genetics Knowledge Parks (GKPs) is to translate advances in genetics research into clinical practice.

6 Apr 2004