Chronic Kidney Disease News and Research

Latest Chronic Kidney Disease News and Research

New therapeutic targets can prevent scarring within transplanted kidneys

Kidneys donated by people born with a small variation in the code of a key gene may be more likely, once in the transplant recipient, to accumulate scar tissue that contributes to kidney failure, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published today in the Journal of Clinical Investigation.

2 Dec 2014

Alport syndrome: an interview with Dr Paul Grint, CMO, Regulus

Alport Syndrome was first described by a physician called Cecil Alport, back in the late 1920s. It's a genetic disease that affects a certain type of collagen involved in the functioning of the kidney, the ear, and the eye.

1 Dec 2014

Promising new therapeutic strategy for chronic kidney disease

Chronic kidney disease (CKD) affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease's progress towards kidney failure. Now, however, a team led by researchers at the Perelman School of Medicine at the University of Pennsylvania, has found an aspect of CKD's development that points to a promising new therapeutic strategy.

1 Dec 2014

Investigational drug maintains normal potassium levels in patients with chronic kidney disease

Research published today found that the investigational drug patiromer decreased high potassium levels and maintained normal potassium levels in patients with chronic kidney disease. The results of a multicenter trial appear in the New England Journal of Medicine.

21 Nov 2014

Kidney disease patients can benefit from simple and structured exercise

Simple yet structured exercise can significantly improve kidney disease patients' quality of life as well as decrease their pain, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

21 Nov 2014

Study evaluates efficacy, safety of zirconium cyclosilicate drug in patients with hyperkalemia

Mikhail Kosiborod, M.D., of Saint Luke's Mid America Heart Institute, Kansas City, and colleagues evaluated the efficacy and safety of the drug zirconium cyclosilicate in patients with hyperkalemia (higher than normal potassium levels). The study appears in JAMA and is being released to coincide with its presentation at the American Heart Association's Scientific Sessions 2014.

18 Nov 2014

New preclinical study shows RG-012 may provide therapeutic benefit for Alport syndrome patients

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced that positive new preclinical data was presented on RG-012 for the treatment of renal dysfunction in Alport syndrome patients at the American Society of Nephrology's Kidney Week 2014 meeting being held November 11-16, 2014 in Philadelphia, PA.

18 Nov 2014

University at Buffalo researchers receive $500,000 grant to study IED-induced vision loss

It's well known that battlefield explosions can cause hearing loss, but veterans may be surprised to learn that their vision may also suffer — sometimes weeks or months after combat exposure.

14 Nov 2014

Hospira launches Paricalcitol Injection

Hospira, Inc., the world's leading provider of injectable drugs and infusion technologies, today announced the launch of Paricalcitol Injection, a generic version of AbbVie's Zemplar. Hospira obtained U.S. Food and Drug Administration approval of paricalcitol on Oct. 21 and launched the product Nov. 1.

5 Nov 2014

New dialysis decision aid can benefit patients with kidney failure

A KIDNEY dialysis decision aid, enabling patients with decreasing kidney function to better assess which treatment is right for them, has been developed by Kidney Research UK as part of a study in which Sheffield Teaching Hospitals NHS Foundation Trust was involved.

4 Nov 2014

Researchers find independent predictors of end stage renal disease in teens

Researchers at örebro University found that high blood pressure, being overweight, elevation of a blood marker indicating inflammation, or the presence of protein in the urine in otherwise healthy teenage males were all independent predictors of end stage renal disease (ESRD) in later in life.

31 Oct 2014

Mediterranean diet is good for your kidneys

New research indicates that adopting a Mediterranean-style diet can reduce the risk of developing chronic kidney disease by 50%.

31 Oct 2014

Fewer women than men receive dialysis treatment for chronic kidney disease

Women with chronic kidney disease receive dialysis treatment far less often than men. However, women suffer more commonly than men from kidney disease. A publication by the MedUni Vienna and the Arbor Research Collaborative for Health, USA, has highlighted this difference based on international patient data.

29 Oct 2014

Working under hot sun causes health problems for sugarcane harvesters

Hard work under hot sun causes health problems for sugar cane workers in Costa Rica, such as headache, nausea, and renal dysfunction. The presence of symptoms is also expected to increase in line with ongoing climate changes, according to a dissertation from Umeå University.

27 Oct 2014

MGH, MIT partner to accelerate development of diagnostic tools and therapies

A novel partnership between Massachusetts General Hospital and Massachusetts Institute of Technology is addressing three major challenges in clinical medicine – improving the diagnosis of disease, developing new approaches to prevent and treat infectious and autoimmune diseases, and developing more accurate methods of diagnosing and treating major neurodegenerative and psychiatric diseases. While individual collaborations between MGH and MIT investigators are nothing new, this formalized strategic partnership is designed to accelerate the development of diagnostic tools and therapies.

16 Oct 2014

Sandwiches significantly contribute to daily energy, sodium intake

Sandwiches make up a substantial part of the American diet and are a significant contributor to daily energy and sodium intake. By closely analyzing data from the federal nationwide dietary intake survey known as "What We Eat in America NHANES 2009-2010," a team of Department of Agriculture researchers found that on any given day 49 percent of U.S. adults eat at least one sandwich, and sandwiches account for one-fifth of total daily sodium intake.

7 Oct 2014

Ardelyx announces positive Phase 2b results for tenapanor in IBS-C patients

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on cardio-renal, gastrointestinal and metabolic diseases, today announced positive results from its 371 patient Phase 2b clinical trial evaluating tenapanor in patients with constipation-predominant irritable bowel syndrome (IBS-C).

1 Oct 2014

New collaborative approach could help improve diabetes care in China

Diabetes has become a major public health crisis in China, with an annual projected cost of 360 billion RMB (nearly 35 billion British pounds) by 2030, but a new collaborative approach to care that uses registries and community support could help improve diabetes care, according to a new three-part Series about diabetes in China published in The Lancet Diabetes & Endocrinology.

11 Sep 2014

Penn State receives $1.8 million from PCORI to help patients with chronic kidney disease

Penn State College of Medicine has been awarded $1.8 million in research funding from the Patient-Centered Outcomes Research Institute (PCORI).

8 Sep 2014

FDA approves Ferric Citrate for control of serum phosphorus levels in CKD patients on dialysis

Keryx Biopharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration approved Ferric Citrate (formerly known as Zerenex) for the control of serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

6 Sep 2014