Colon Cancer

Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Prevention

Colorectal Cancer Management

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Latest Colon Cancer News and Research

Minute plastic air particles may be causing respiratory and other illnesses

A review of 3,000 studies also suggests these minute plastic air particles may be causing male and female infertility.

18 Dec 2024

Microbial bile acids affect colon cancer risk in opposite ways

Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats.

16 Dec 2024

Lipid imbalances hold the key to chronic inflammation in colon cancer

Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new therapeutic strategies targeting pro-inflammatory and pro-resolving lipid imbalances.

12 Dec 2024

Accelerated aging linked to early-onset colorectal cancer, study shows

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that one's biological age, which can be higher than his or her chronological age – a concept called accelerated aging – may predict who's at risk for developing colon polyps, a known risk factor for colorectal cancer.

11 Dec 2024

Study links Western diet to chronic inflammation and colorectal cancer growth

Colorectal cancer, the second leading cause of cancer-related deaths in the United States, may be fueled by the food on our plates.

10 Dec 2024

Report highlights increasing use of targeted therapies before surgery for cancer treatment

Breast, bladder, and pancreatic cancers are increasingly being treated with a broad range of therapies before a patient undergoes surgery, and cancer stage at diagnosis continues to be a leading factor in determining a person's survival rate for all types of cancer, according to the first-ever annual cancer report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) Cancer Programs.

3 Dec 2024

How different types of bread impact cancer risk

Researchers find bread consumption is not linked to cancer risk, with whole-grain bread potentially reducing colorectal cancer and total cancer mortality.

20 Nov 2024

Targeting CD47 protein could improve colorectal cancer treatment

A new study from the USC Norris Comprehensive Cancer Center has found evidence that targeting CD47, a protein that is part of the innate immune system, could be a key step in fighting colorectal cancer.

7 Nov 2024

Michigan study finds virtual care does not lead to wastage of healthcare resources

Before 2024 ends, Congress will decide whether to keep or change rules about telehealth, or let them expire. And even though the decision will focus on Medicare's payment for virtual patient care, it will likely impact telehealth access for people with other kinds of health insurance too.

7 Nov 2024

How bacteria trigger colon cancer

Investigation shows how bacterial adhesins contribute to colon cancer mutations, suggesting new avenues for therapeutic intervention in colorectal cancer.

7 Nov 2024

Study uncovers how certain E. coli bacteria in the gut promote colon cancer

Scientists have uncovered how certain E. coli bacteria in the gut promote colon cancer by binding to intestinal cells and releasing a DNA-damaging toxin.

6 Nov 2024

Study uncovers key role of gut microbiota in regulating stress responses

A pioneering study has uncovered the vital role that gut microbiota plays in regulating stress responses by interacting with the body's circadian rhythms.

5 Nov 2024

Low awareness of lung cancer screening raises concerns

There is a lung cancer screening test that is saving lives – and yet most people who could be getting the test have never heard of it or never talked about it with a doctor.

4 Nov 2024

Study identifies six cancer susceptibility genes

Identification of six cancer susceptibility genes offers new insights into genetic risk factors, potentially enhancing early detection and treatment strategies.

29 Oct 2024

Study sheds new light on p53 tumor suppressor gene's role in ulcerative colitis

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité – Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis.

26 Oct 2024

Studies reveal unique challenges faced by younger patients with colorectal cancer

Younger adults with colon cancer tend to be diagnosed at a later stage and have more aggressive types of tumors.

18 Oct 2024

Helene and CVS land double whammy for 25,000 patients who survive on IV nutrition

The CVS representative popped into Lisa Trumble's third-floor Berkshire Medical Center hospital room in Pittsfield, Massachusetts, to announce that everything was arranged for Trumble to return home, where she relies on IV nutrition because of severe intestinal problems that leave her unable to eat.

18 Oct 2024

New insights on 5-fluorouracil's mechanism in different cancers

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.

7 Oct 2024

Researchers develop technology to change protein identity in vivo

Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins. The innovation, published in Nature Communications on October 2, allowed researchers to target mouse tumors with a protein and then transport that protein out of the body.

3 Oct 2024