Crohn's Disease

Crohn’s disease is a chronic inflammatory disease of the bowel affecting at least 115,000 people in the UK. The condition usually develops in teenagers and young adults, but can be diagnosed at any age and is equally common in men and women.

What is Crohn's Disease?

Crohn’s disease is a disease that leads to severe inflammation of the lining of the digestive system.

Crohn's Disease Symptoms

Crohn's Disease Cause

Crohn's Disease Diagnosis

Crohn's Disease Treatment

Crohn's Disease Complications

History of Crohn's Disease

Intestinal Mycoplasma and Crohn's Disease

Latest Crohn's Disease News and Research

Cedars-Sinai study investigates diet's role in treating gut disorders

A new study from Cedars-Sinai examined whether a specialized diet could improve symptoms of gastrointestinal disorders linked to an imbalance in gut microbiota.

1 Apr 2025

Study reveals disparities in healthcare utilization among racial and ethnic groups with IBD

A study published today in the American Journal of Gastroenterology reveals significant disparities in healthcare utilization among racial and ethnic groups with inflammatory bowel disease (IBD) in the United States.

1 Apr 2025

Machine learning identifies key comorbidities predicting premature death in IBD patients

Researchers use machine learning models to investigate patterns between multimorbidity and premature deaths among decedents with irritable bowel disease.

28 Mar 2025

Mount Sinai-led research uncovers mechanisms behind Crohn's disease inflammation

A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease, according to findings published in Science Immunology on March 21.

22 Mar 2025

Plant-based diets and IBD

This study highlights the link between plant-based diets and reduced IBD risk, suggesting dietary choices play a crucial role in managing chronic inflammation.

19 Mar 2025

IL-12 targeting could open pathways for new Alzheimer's treatments

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's disease.

17 Mar 2025

Experts release new guidelines on JAK inhibitors for chronic inflammatory diseases

Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis.

17 Mar 2025

Semi-synthetic bile acid could be a promising therapeutic option for TH17-mediated intestinal diseases

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

14 Mar 2025

Nationally recognized gastroenterologist joins NYU Langone to lead Pediatric IBD Program

Nationally recognized pediatric gastroenterologist, Michael Dolinger, MD, MBA, joins Hassenfeld Children's Hospital at NYU Langone as director of the Pediatric Inflammatory Bowel Disease Program within the Pediatric Gastroenterology Program.

5 Mar 2025

Study finds potential biomarker for joint inflammation in Crohn's disease

People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a potential biomarker, according to new study by Weill Cornell Medicine researchers.

5 Mar 2025

Epstein-Barr virus infection predisposes people to develop Crohn's disease

Crohn's disease, a debilitating inflammatory bowel disease, has many known contributing factors, including bacterial changes in the microbiome that foster an inflammatory environment.

3 Mar 2025

Grapefruit juice and its effects on prescription drugs

Grapefruit juice can interfere with how certain medications work by affecting drug metabolism and absorption, leading to either increased side effects or reduced effectiveness. The FDA requires warnings on some drugs due to these interactions, making it essential to check labels and consult healthcare providers.

28 Feb 2025

Study focuses on diagnostic delays experienced by people with epilepsy

Any patient suffering from new or worsening medical symptoms hopes for a relatively quick and accurate diagnosis.

20 Feb 2025

Unfolded protein response disruptions contribute to colorectal cancer and gut-related disorders

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system.

20 Feb 2025

Strengthening the gut barrier may halt Crohn’s disease progression

Researchers at the University of Gothenburg, Sweden, have uncovered a critical mechanism that may pave the way for innovative treatments for Crohn's disease.

18 Feb 2025

Gut microbiota key to predicting sensitivity to common food additives

Widely used by the food industry, emulsifiers – a type of food additive – are found in many daily foods (sliced bread, ice creams, crème fraîche, plant milks, etc.).

11 Feb 2025

Study explores microbiome reboot to prolong effect of Crohn's disease therapy

A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn's disease. Patients consume only this formula for six to eight weeks, completely avoiding solid foods. However, the exact reasons why this is helpful were previously unclear.

11 Feb 2025