Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

ChatGPT outperforms trainee doctors in respiratory disease assessments

The chatbot ChatGPT performed better than trainee doctors in assessing complex cases of respiratory disease in areas such as cystic fibrosis, asthma and chest infections in a study presented at the European Respiratory Society (ERS) Congress in Vienna, Austria.

9 Sep 2024

New research identifies key protein complex in cellular quality control

Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease.

12 Aug 2024

Mini intestines uncover mechanisms behind COVID-19-related diarrhea and potential treatments

Working with human stem cells that form a kind of "mini intestine-in-a-dish," Johns Hopkins Medicine scientists say they have found several molecular mechanisms for COVID-19-related diarrhea, suggesting potential ways to control it.

6 Aug 2024

New mucus-based bioink for 3D printing functional lung tissue

Lung diseases kill millions of people around the world each year. Treatment options are limited, and animal models for studying these illnesses and experimental medications are inadequate.

30 Jul 2024

Dogs with gallbladder disease shed light on human cystic fibrosis

A canine gallbladder disease that involves the accumulation of abnormal mucus similar to that seen in human cystic fibrosis (CF) patients is caused by improper expression of the gene associated with CF in humans.

29 Jul 2024

Enterprise Therapeutics doses first person with cystic fibrosis in Phase 2 trial for novel therapy ETD001

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of those suffering from respiratory disease, today announced dosing of the first person with cystic fibrosis (pwCF) in its Phase 2a trial of ETD001.

24 Jul 2024

Cystic fibrosis drug reduces hyper-inflammation in COVID-19 pneumonia patients

A drug commonly used to treat cystic fibrosis improved outcomes for patients with severe COVID-19 pneumonia and could be used to treat other respiratory infections, according to clinical trial results from researchers at UCL, UCLH and the Francis Crick Institute.

18 Jul 2024

One-time prime editing targets common genetic cause of cystic fibrosis

Researchers optimized prime editing for the efficient correction of the cystic fibrosis transmembrane conductance regulator F508del mutation in human airway epithelial cells, achieving high correction efficiencies and functional restoration with minimal off-target effects.

15 Jul 2024

UQ study offers insights into how Haemophilus influenzae manipulates the immune system

Researchers from The University of Queensland have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness.

12 Jul 2024

Prime editing offers promising path to permanent treatment for cystic fibrosis

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection.

11 Jul 2024

Smartphone-based behavioral therapy leads to improvements for patients with fibromyalgia

New research led by the University of Cincinnati and Swing Therapeutics found that a self-guided smartphone-based behavioral therapy led to significant improvements for patients with fibromyalgia.

8 Jul 2024

Small molecule discovery offers hope for treatment of Angelman syndrome

Angelman syndrome is a rare genetic disorder caused by mutations in the maternally-inherited UBE3A gene and characterized by poor muscle control, limited speech, epilepsy, and intellectual disabilities.

8 Jul 2024

Phages use selfish DNA to outmaneuver competitors

Curious bits of DNA tucked inside genomes across all kingdoms of life historically have been disregarded since they don't seem to have a role to play in the competition for survival.

5 Jul 2024

Enterprise Therapeutics appoints Dr Renu Gupta as Chief Medical Officer and Dr Janet Hammond as Non-Executive Director

Appointments bring additional respiratory and late clinical-stage drug development experience as Company commences Phase 2a clinical trial of its lead asset.

From Enterprise Therapeutics Ltd 17 Jun 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024

Biden’s on target about what repealing ACA would mean for preexisting condition protections

President Joe Biden's reelection campaign wants voters to contrast his record on health care policy with his predecessor's.

13 Jun 2024

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in the Journal of Cystic Fibrosis1.

12 Jun 2024

Study uncovers two types of dysbiosis in cystic fibrosis

Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis.

11 Jun 2024

Efficient whole-gene insertions can be achieved with improved gene-editing technology

Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applications.

10 Jun 2024

Multiple general anesthesia exposure does not compromise brain function in young children, study finds

A University of Queensland-led study has found multiple doses of anesthetics do not compromise brain function in young children.

10 Jun 2024

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

ChatGPT outperforms trainee doctors in respiratory disease assessments

New research identifies key protein complex in cellular quality control

Mini intestines uncover mechanisms behind COVID-19-related diarrhea and potential treatments

New mucus-based bioink for 3D printing functional lung tissue

Dogs with gallbladder disease shed light on human cystic fibrosis

Enterprise Therapeutics doses first person with cystic fibrosis in Phase 2 trial for novel therapy ETD001

Cystic fibrosis drug reduces hyper-inflammation in COVID-19 pneumonia patients

One-time prime editing targets common genetic cause of cystic fibrosis

UQ study offers insights into how Haemophilus influenzae manipulates the immune system

Prime editing offers promising path to permanent treatment for cystic fibrosis

Smartphone-based behavioral therapy leads to improvements for patients with fibromyalgia

Small molecule discovery offers hope for treatment of Angelman syndrome

Phages use selfish DNA to outmaneuver competitors

Enterprise Therapeutics appoints Dr Renu Gupta as Chief Medical Officer and Dr Janet Hammond as Non-Executive Director

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Biden’s on target about what repealing ACA would mean for preexisting condition protections

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Study uncovers two types of dysbiosis in cystic fibrosis

Efficient whole-gene insertions can be achieved with improved gene-editing technology

Multiple general anesthesia exposure does not compromise brain function in young children, study finds

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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