Dementia News and Research

Latest Dementia News and Research

Elevated BACE1 activity in mild cognitive impairment could be early indicator of AD, says study

The critical enzyme beta-secretase1 (BACE1) is known to be elevated in brains with sporadic Alzheimer disease (AD). Scientists have now found increased levels of BACE1 in brains with mild cognitive impairment (MCI), suggesting that BACE1 activity is important for conversion of mild cognitive impairment to AD and may be an early indicator of AD.

12 Dec 2013

Study finds that people with COPD twice likely to develop mild cognitive impairment, memory loss

A recent Mayo Clinic study found that people with chronic obstructive pulmonary disease (COPD) are about twice as likely to develop mild cognitive impairment (MCI) -- and chances are that it will include memory loss. The study was recently published in Mayo Clinic Proceedings.

12 Dec 2013

EPSRC donates £5 million for dementia research

Health ministers from the G8 nations will meet in London today (11 December) to discuss the global health challenge posed by dementia. The summit aims to develop co-ordinated global action on dementia. One area of focus at the summit is preventing and delaying dementia.

11 Dec 2013

Acid-inhibiting medications linked with increased risk for vitamin B12 deficiency

Use for 2 or more years of proton pump inhibitors and histamine 2 receptor antagonists (two types of acid-inhibiting medications) was associated with a subsequent new diagnosis of vitamin B12 deficiency, according to a study appearing in the December 11 issue of JAMA.

11 Dec 2013

Otsuka, Lundbeck to develop investigational vaccine candidate for Alzheimer's disease

H. Lundbeck A/S (Lundbeck) and Otsuka Pharmaceutical Co., Ltd. (Otsuka) today announced that they will further expand their collaboration to include the development of Lu AF20513, an investigational vaccine candidate for Alzheimer's disease.

11 Dec 2013

Merck provides update on MK-8931 investigational oral therapy for Alzheimer’s disease

Merck, known as MSD outside the United States and Canada, today provided an update on the development program for MK-8931, a novel investigational oral β-amyloid precursor protein site-cleaving enzyme (BACE) inhibitor.

11 Dec 2013

Study links vitamin B12 deficiency to acid-suppressing medications

Long-term use of commonly prescribed heartburn and ulcer medications is linked to a higher risk of vitamin B12 deficiency, according to a new study published online in the Journal of the American Medical Association.

10 Dec 2013

Janssen announces first-of-its-kind pediatric HIV treatment donation program

Janssen, the pharmaceutical companies of Johnson & Johnson, today announced a first-of-its-kind pediatric HIV treatment donation program to improve access to the company's approved HIV medicines for children and adolescents failing HIV treatment in sub-Saharan Africa.

9 Dec 2013

Heptares starts HTL9936 Phase 1 study for improving cognitive function in Alzheimer's patients

Heptares Therapeutics, the leading GPCR structure-guided drug discovery and development company, announces that it has initiated a Phase 1 clinical study of HTL9936, the first fully selective muscarinic M1 receptor agonist to enter clinical development. HTL9936 is an orally available, small molecule drug candidate discovered using the Heptares GPCR structure-based drug design platform.

9 Dec 2013

Penn researchers identify protein that could clear Alzheimer's plaques

The body is structured to ensure that any invading organisms have a tough time reaching the brain, an organ obviously critical to survival. Known as the blood-brain barrier, cells that line the brain and spinal cord are tightly packed, making it difficult for anything besides very small molecules to cross from the bloodstream into the central nervous system. While beneficial, this blockade also stands in the way of delivering drugs intended to treat neurological disorders, such as Alzheimer's.

9 Dec 2013

Scientists receive 2013 Horwitz Prize for discoveries on how brain calculates location, navigation

Edvard and May-Britt Moser of the Norwegian University of Science and Technology (NTNU), and John O'Keefe, from University College London have been awarded the 2013 Louisa Gross Horwitz Prize for discoveries that have illuminated how the brain calculates location and navigation.

9 Dec 2013

Aortic valve implantation does not impair mental capacity of patients

Aortic valve stenosis is the most frequent heart valve defect of older people in Europe - the cause is usually increasing calcification of this important valve. In patients at high and excessive risk, conventional cardiac surgery is often no therapeutic option.

6 Dec 2013

Study reports new links between brain cell activity and choices where two options have equal appeal

Life presents us with choices all the time: salad or pizza for lunch? Tea or coffee afterward? How we make these everyday decisions has been a topic of great interest to economists, who have devised theories about how we assign values to our options and use those values to make decisions.

6 Dec 2013

Scientists receive 2013 Louisa Gross Horwitz Prize for advancements in field of neuroscience

For discoveries about how the brain calculates and remembers where it is—which could be part of the foundation of memory—Columbia University will award the 2013 Louisa Gross Horwitz Prize to Edvard I. Moser, PhD, and May-Britt Moser, PhD, of the Norwegian University of Science and Technology in Norway, and John Michael O'Keefe, PhD, of University College London in the UK.

6 Dec 2013

UCSB researcher tracks source of E280A gene mutation responsible for early-onset Alzheimer's

The age and origin of the E280A gene mutation responsible for early-onset Alzheimer's in a Colombian family with an unusually high incidence of the disease has been traced to a single founder dating from the 16th century.

5 Dec 2013

Philanthropist pledges $5M to fund new endowed chair in Alzheimer's disease research at Keck School

Los Angeles residents Selim Zilkha and Mary Hayley are raising the stakes in the fight against Alzheimer's disease, the only cause of death among the top 10 in the United States that cannot currently be prevented, cured or slowed.

4 Dec 2013

Combining neuroimaging and neuropsychology improves detection of Alzheimer's disease

By combining brain imaging analysis with a neuropsychological assessment, Sylvie Belleville achieved remarkable sensitivity and specificity. The level of accuracy of this classification system is the major breakthrough of the study. "When used individually, neuroimaging and neuropsychology are effective but only up to a certain point. It is when combining and analyzing the results from both methods that we could achieve such an exceptional level of accuracy," explained Sylvie Belleville.

4 Dec 2013

Research: Omega-3 fatty acids in dietary supplements can cross blood brain barrier in Alzheimer's patients

New research from Karolinska Institutet in Sweden shows that omega-3 fatty acids in dietary supplements can cross the blood brain barrier in people with Alzheimer's disease, affecting known markers for both the disease itself and inflammation.

4 Dec 2013

New book provides advice on how to engage and motivate adults with cognitive disorders

The Lewy Body Dementia Association is partnering with R.O.S. Therapy Systems, the company that created the first and only activity system for older adults with physical and cognitive disorders, to help create awareness of Lewy Body Dementia and help family caregivers by introducing them to Activities 101 for the Family Caregiver.

4 Dec 2013

Exercise may benefit older people with dementia

Exercise may benefit older people with dementia by improving their cognitive functioning and ability to carry out everyday activities, according to a new systematic review published in The Cochrane Library. However, the authors of the review did not see any clear effect of exercise on depression in older people with dementia and say that more evidence is needed to understand how exercise could reduce the burden on family caregivers and health systems.

3 Dec 2013

Dementia News and Research

Latest Dementia News and Research

Elevated BACE1 activity in mild cognitive impairment could be early indicator of AD, says study

Study finds that people with COPD twice likely to develop mild cognitive impairment, memory loss

EPSRC donates £5 million for dementia research

Acid-inhibiting medications linked with increased risk for vitamin B12 deficiency

Otsuka, Lundbeck to develop investigational vaccine candidate for Alzheimer's disease

Merck provides update on MK-8931 investigational oral therapy for Alzheimer’s disease

Study links vitamin B12 deficiency to acid-suppressing medications

Janssen announces first-of-its-kind pediatric HIV treatment donation program

Heptares starts HTL9936 Phase 1 study for improving cognitive function in Alzheimer's patients

Penn researchers identify protein that could clear Alzheimer's plaques

Scientists receive 2013 Horwitz Prize for discoveries on how brain calculates location, navigation

Aortic valve implantation does not impair mental capacity of patients

Study reports new links between brain cell activity and choices where two options have equal appeal

Scientists receive 2013 Louisa Gross Horwitz Prize for advancements in field of neuroscience

UCSB researcher tracks source of E280A gene mutation responsible for early-onset Alzheimer's

Philanthropist pledges $5M to fund new endowed chair in Alzheimer's disease research at Keck School

Combining neuroimaging and neuropsychology improves detection of Alzheimer's disease

Research: Omega-3 fatty acids in dietary supplements can cross blood brain barrier in Alzheimer's patients

New book provides advice on how to engage and motivate adults with cognitive disorders

Exercise may benefit older people with dementia

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Dementia News and Research

Latest Dementia News and Research

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Newsletters you may be interested in