Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Causes of Depression

How Does Your Diet Affect Depression?

Depression Diagnosis

Genes and Depression

Symptoms of Depression

Treatment of Depression

Depression in children

How Can I Tell if My Child is Depressed?

How is Depression in Children Diagnosed?

Treatment Options for Children with Depression

Contributing Factors to Post-Adoption Depression

See more featured articles »

Ghrelin and Depression

Prisoner Depression and Low Mood

Intrusive Thoughts and Depression

Supporting Children with Mental Health Disorders

Depression and Sleep Length

Link Between Chronic Illness and Depression

Situational Depression: Symptoms, Causes, Treatments

Can Depression and Anxiety Occur Together?

Antidepressants and Weight Changes

Food Insecurity and Depression

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

5 Facts You May Not Know About Depression

Latest Depression News and Research

AI model combines speech and brain activity to diagnose depression

Depression is one of the most common mental illnesses. As many as 280 million people worldwide are affected by this disease, which is why researchers at Kaunas University of Technology (KTU) have developed an artificial intelligence (AI) model that helps to identify depression based on both speech and brain neural activity.

20 Nov 2024

Pregnancy stress and mental health affect the oral microbiome

The number and type of microbes present in the saliva of pregnant women differ according to whether they are experiencing life stress and symptoms of anxiety, depression and post-traumatic stress disorder (PTSD), finds a study published in the open access journal BMJ Mental Health.

20 Nov 2024

Creativity camp boosts well-being in teens with depression

Published in Child Psychiatry and Human Development, a research team led by the University of Minnesota Medical School found that Creativity Camp, a two-week arts intervention delivered as a day camp, had a positive impact on mental health and well-being in adolescents with depression.

20 Nov 2024

Internet use boosts mental health for older adults worldwide

Older adults across 23 countries who use the Internet experience improved mental health, including fewer depressive symptoms and higher life satisfaction, with benefits varying by demographic and genetic factors.

19 Nov 2024

Study provides insight into how low-dose ketamine alleviates symptoms of major depression

University at Buffalo neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression in as little as a few hours with effects lasting for several days.

19 Nov 2024

Small Solutions for Big Problems in Drug Discovery and Delivery

Ijeoma Uchegbu discusses nanomedicine's role in improving medication adherence and developing non-addictive pain relief solutions at ELRIG Drug Discovery 2024.

19 Nov 2024

Multiple sclerosis drug could help individuals with reduced working memory

Fampridine is currently used to improve walking ability in multiple sclerosis. A new study shows that it could also help individuals with reduced working memory, as seen in mental health conditions like schizophrenia or depression.

19 Nov 2024

Ultra-processed foods drive obesity and metabolic risks

Italian researchers reveal a strong link between ultra-processed foods and obesity, highlighting increased cardiometabolic risks in adults with higher UPF consumption. The findings call for urgent dietary changes to combat obesity and promote healthier lifestyles.

18 Nov 2024

New mindfulness therapy offers hope for teenagers struggling with depression

Researchers have developed a mindfulness therapy tailored specifically to appeal to teenagers to help them cope with increasing levels of depression and mental health problems.

18 Nov 2024

New clinical trial offers hope for patients with rare immune disease IgG4-RD

A team led by Mass General Brigham researchers demonstrated that inebilizumab reduced the risk of symptoms by 87% in patients with the rare affliction known as immunoglobulin G4–related disease (IgG4-RD)

18 Nov 2024

Growth hormone-releasing hormone transforms therapeutic potential in health and chronic disease

Researchers review the biological activities of growth hormone-releasing hormone and its analogs.

17 Nov 2024

Study shows benefits of nature for children's mental health

A team of researchers from McGill and Université de Montréal's Observatoire pour l'éducation et la santé des enfants (OPES, or observatory on children's health and eduation), led by Sylvana Côté, found that spending two hours a week of class time in a natural environment can reduce emotional distress among 10- to 12-year-olds who had the most significant mental health problems before the program began.

15 Nov 2024

Computer-assisted CBT and mental health apps effective in reducing anxiety, depression symptoms

Computer-assisted cognitive-behavior therapy (CCBT) and mobile mental health applications warrant continued development and ongoing efforts to increase acceptance among patients and clinicians, according to a review published in the Journal of Psychiatric Practice, part of the Lippincott portfolio from Wolters Kluwer.

15 Nov 2024

USF study to track long-term impact of digital media on youth wellbeing

A groundbreaking new study conducted by the University of South Florida will track young people through 2050 to learn more about the long-term impacts of smartphones, social media and other digital media on individual wellbeing.

15 Nov 2024

New discovery reveals NMDAR's critical function in maintaining brain stability

Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor (NMDAR)-;long studied primarily for its role in learning and memory-;also plays a crucial role in stabilizing brain activity.

15 Nov 2024

Cognitive behavioral therapy shows promise for prolonged grief disorder

Integrative cognitive behavioral therapy shows greater efficacy than present-centered therapy in reducing grief severity and comorbid symptoms after treatment.

15 Nov 2024

Phase 3 study finds inebilizumab effective for immunoglobulin G4–related disease

An international, phase 3 clinical trial led by investigators at Mass General Brigham could improve the treatment of a rare disease that can cause debilitating symptoms.

14 Nov 2024

New study links circadian gene variants to winter depression

Variants of the PER3 gene disrupt adrenal adaptation to winter light, leading to serotonin disruption and depression-like behaviors in humanized mice models.

13 Nov 2024

Study suggests beta-blockers may elevate depression symptoms in post-MI patients

In MI patients with preserved heart function, beta-blockers are linked to higher depressive symptoms, indicating a need for careful mental health assessment.

13 Nov 2024

Older Americans living alone often rely on neighbors or others willing to help

Donald Hammen, 80, and his longtime next-door neighbor in south Minneapolis, Julie McMahon, have an understanding. Every morning, she checks to see whether he's raised the blinds in his dining room window. If not, she'll call Hammen or let herself into his house to see what's going on.

12 Nov 2024