Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Can Depression and Anxiety Occur Together?

Food Insecurity and Depression

How Does Your Diet Affect Depression?

Ghrelin and Depression

Genes and Depression

Depression in children

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Situational Depression: Symptoms, Causes, Treatments

Causes of Depression

Contributing Factors to Post-Adoption Depression

Intrusive Thoughts and Depression

See more featured articles »

Antidepressants and Weight Changes

Depression Diagnosis

Treatment Options for Children with Depression

Prisoner Depression and Low Mood

Link Between Chronic Illness and Depression

Depression and Sleep Length

Treatment of Depression

Symptoms of Depression

5 Facts You May Not Know About Depression

How is Depression in Children Diagnosed?

Supporting Children with Mental Health Disorders

How Can I Tell if My Child is Depressed?

Latest Depression News and Research

Trial evaluates interdisciplinary care for veterans with brain trauma and PTSD

The Medical College of Wisconsin (MCW) is leading a new multi-center clinical trial to evaluate an interdisciplinary rehabilitation model for military veterans and first responders with mild traumatic brain injury (mTBI) and co-occurring disorders such as depression, anxiety, and post-traumatic stress disorder (PTSD).

30 Jun 2026

University of Surrey team develops first grief tool for unpaid carers

The first dedicated support tool for unpaid carers who grieve for an older person they care for before they have died is being developed by a team led by the University of Surrey.

30 Jun 2026

Researchers identify key predictors for mother-infant bonding difficulties

Mother-to-infant bonding difficulties (MIBD) are commonly associated with postnatal depression. MIBD has been linked to developmental delays and child abuse.

30 Jun 2026

Review assesses the efficacy of creatine as an add-on therapy for depression

Walk into any gym supplement aisle and creatine is there, sold by the tub to people chasing bigger muscles. It is one of the most studied compounds in sports science.

30 Jun 2026

Teen reliance on AI could hinder healthy relationship development

As teenagers increasingly turn to artificial intelligence chatbots for advice about friendships, family conflicts and romantic ties, researchers are raising concerns that the technology could disturb how young people learn to navigate human relationships.

29 Jun 2026

Daily weather fluctuations affect mental health service demand in England

New research led by the University of East Anglia (UEA) suggests even modest, short-term changes in weather can have a measurable impact on NHS mental health service demand across England.

29 Jun 2026

One in three adults in England now lives with obesity

Obesity trends show significant disparities among demographics, stressing the importance of targeted prevention to address widening health inequalities.

29 Jun 2026

Brighter daytime light is linked to a lower dementia risk

The study finds that greater exposure to daytime light may lower dementia risk, pointing to light's role in enhancing circadian rhythms and cognitive function.

29 Jun 2026

Multi-decade study tracks subsequent cancer risks in survivors

As people continue to live longer and the survival rate of cancer diagnoses increases, researchers from VCU Massey Comprehensive Cancer Center led a multi-decade analysis studying the rates of subsequent primary cancers (SPCs), which are new cancers unrelated to the original diagnosis.

26 Jun 2026

Neuroticism and adversity dominate depression and anxiety risk in UK Biobank study

In a UK Biobank study of 87,648 adults followed for 13.7 years, psychosocial factors accounted for the largest estimated population burden of depression and anxiety in both women and men. Neuroticism symptoms, childhood and adult adversity, obesity, chronic inflammation, and some reproductive factors in women were linked to incident mental health outcomes, although the PAF estimates remain theoretical and not proof of causality.

25 Jun 2026

Blueberries may boost children's memory and mood

Research suggests blueberry compounds could enhance mood and cognitive function in children, yet stronger evidence is required for clinical recommendations.

25 Jun 2026

Maternal blood test reveals prenatal methylation clues linked to autism risk

Researchers found that maternal plasma cell-free DNA methylation patterns in late pregnancy were associated with later autism diagnosis and maternal obesity in a high-likelihood ASD cohort. The findings suggest cfDNA may offer a minimally invasive way to study prenatal epigenetic changes linked to neurodevelopmental risk, but larger validation studies are needed.

25 Jun 2026

Scientists map blood chemistry links to hundreds of diseases

A UK Biobank study of nearly 390,000 people mapped 251 NMR-derived plasma metabolic traits against hundreds of health traits, prevalent diseases, and future disease outcomes. The atlas revealed tens of thousands of replicated associations, showed stronger prediction for selected short-term and cardiometabolic outcomes, and identified putative causal links that may guide future precision medicine research.

24 Jun 2026

Swedish scientist wins prestigious award for sickness behavior research

David Engblom, Professor of Neurobiology at Linköping University, Sweden, is awarded the 2026 Onkel Adam Prize for outstanding research at the Faculty of Medicine at Linköping University.

24 Jun 2026

Functional brain imaging can help guide accelerated TMS for depression

Mass General Brigham study suggests that functional brain imaging can help guide accelerated transcranial magnetic stimulation for depression.

24 Jun 2026

UCI Health launches world's first embryonic stem cell trial for Huntington's disease

UCI Health, the clinical enterprise of the University of California, Irvine, has opened the world's first in-human embryonic stem cell-derived clinical trial for Huntington's disease.

23 Jun 2026

The menstrual cycle changes heart-rate variability but not strength

Menstrual cycle phases influence heart autonomic regulation, showing HRV variations, yet muscle performance and mood states remain largely unchanged.

23 Jun 2026

Longer breastfeeding links to fewer ADHD symptoms in children

Longer durations of full breastfeeding are linked to fewer ADHD symptoms in children, suggesting early feeding patterns may influence neurodevelopment.

23 Jun 2026

Most adults with depression favor informal community peer support

As mental health needs continue to rise in Singapore, researchers from Duke-NUS Medical School, working with collaborators, including the Institute of Mental Health (IMH), have found that most adults living with symptoms of anxiety or depression are open to receiving support from peers, even if they have not sought professional help.

22 Jun 2026

New guidance to help adolescents and young adults living with and beyond cancer

Adolescents and young adults (AYA) living with and beyond cancer have unique needs and perspectives that clinicians should be aware of when providing health care.

22 Jun 2026