Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Situational Depression: Symptoms, Causes, Treatments

Prisoner Depression and Low Mood

How Can I Tell if My Child is Depressed?

Link Between Chronic Illness and Depression

Supporting Children with Mental Health Disorders

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Depression in children

Treatment Options for Children with Depression

5 Facts You May Not Know About Depression

How Does Your Diet Affect Depression?

Food Insecurity and Depression

See more featured articles »

Symptoms of Depression

Ghrelin and Depression

Genes and Depression

Can Depression and Anxiety Occur Together?

Depression Diagnosis

Antidepressants and Weight Changes

Causes of Depression

Intrusive Thoughts and Depression

Contributing Factors to Post-Adoption Depression

How is Depression in Children Diagnosed?

Depression and Sleep Length

Treatment of Depression

Latest Depression News and Research

Australian study highlights delayed diagnosis in postpartum psychosis care

Women with postpartum psychosis are making repeated pleas for help before receiving a diagnosis, with the first Australian study of their help-seeking experiences finding many contacted health services an average of seven times before getting the care they needed.

22 Oct 2026

Depression profile linked to disrupted sleep and poorer treatment responses

This study uncovers a circadian depression subtype, revealing links between sleep patterns, symptom severity, and antidepressant response in a large cohort.

22 Oct 2026

LSD speeds up brain waves and increases neural complexity, study finds

First synthesized in a laboratory in 1938 by the Swiss chemist Albert Hofmann, lysergic acid diethylamide, better known by its acronym LSD, is one of the most potent and most extensively studied psychedelics.

22 Oct 2026

New study explores psychedelic therapy for co-occurring cocaine addiction and depression

A team of UTHealth Houston researchers has been awarded a five-year, $3.4 million grant to study whether psilocybin-assisted therapy is a viable treatment option for individuals with co-occurring cocaine use disorder and major depressive disorder.

22 Oct 2026

Digital mindfulness program cuts depression relapse risk in mothers by 26%

A free, online program developed by University of Colorado Boulder researchers has been shown to reduce risk of depression relapse by double digits among new moms and moms-to-be with a history of depression.

22 Oct 2026

Accelerated TMS cuts depression treatment time from six weeks to three

Transcranial magnetic stimulation (TMS) has proved to be a very effective non-invasive treatment for people with severe depression who have not had success with medication. But traditional TMS has one significant drawback: time.

21 Oct 2026

AI-powered eye tracking could personalize virtual reality therapy for chronic pain

Combining artificial intelligence (AI) with eye tracking in virtual reality could one day help personalize treatment for millions living with chronic pain, according to world-first research from the University of East Anglia.

21 Oct 2026

Japanese study links postpartum depression to mother-infant bonding difficulties

A Japanese study found that higher postpartum depression scores were associated with greater mother–infant bonding difficulties.

21 Oct 2026

Marital breakups can impact vulnerability decades later in old age

Marital breakups do not only have immediate consequences, typical of the moment when cohabitation ends.

21 Oct 2026

Postpartum psychosis symptoms frequently dismissed as standard baby blues

In an interview-based study in the Journal of Advanced Nursing including 15 Australian women diagnosed with postpartum psychosis over the past 10 years, women reported that they made multiple attempts to seek medical help and support, yet they encountered delayed recognition, inadequate assessment and, at times, dismissal or minimization of their concerns.

21 Oct 2026

Oxaloacetate supplement may help reduce chemo brain in breast cancer survivors

A new study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that a nutritional supplement containing oxaloacetate, a molecule naturally found in the body that helps cells produce energy, may help improve cognitive function and reduce the fatigue experienced by some breast cancer survivors following treatment.

21 Oct 2026

UC Davis Health introduces five-day accelerated treatment for severe depression

UC Davis Health has added an accelerated treatment approach for depression at its Advanced Psychiatric Therapeutics (APT) clinic in East Sacramento.

20 Oct 2026

Researchers identify new depression subtype linked to the body clock

Research by experts at the University of Sydney has identified a new subtype of depression called "circadian depression".

20 Oct 2026

Restless legs syndrome triples the risk of perinatal depression in pregnant women

New research found a higher risk of perinatal depression in pregnant women with restless legs syndrome.

20 Oct 2026

Targeted ultrasound waves safely reduce delusions in people with schizophrenia

Targeting a deep brain region with sound waves may safely reduce delusions in people with schizophrenia and schizoaffective disorder, initial study results show.

20 Oct 2026

Caregivers with heart disease face high psychological distress risks

Family caregivers often put their own health second. For those already living with cardiovascular conditions, caregiving can add to their physical and emotional strain.

20 Oct 2026

Anxiety and depression linked to higher levels of pregnancy "brain fog"

Symptoms of anxiety and depression are associated with higher levels of "pregnancy brain," which is also known as "baby brain," "brain fog" or "momnesia," according to a new study by Penn State researchers.

20 Oct 2026

Preschool social-emotional lessons improve long-term adult well-being

Almost two decades later, preschool students who received supplemental instruction to build their social, emotional and language skills reported a higher quality of life than peers who did not receive the same skill instruction, according to an interdisciplinary team of Penn State researchers.

20 Oct 2026

AI-powered virtual reality could help women manage menopause symptoms

Cognitive behavioral therapy (CBT) has proven effective in managing a number of menopause symptoms, including hot flashes, insomnia, depression, and sexual dysfunction.

20 Oct 2026

Your age may not tell the whole story about how healthy you are

Researchers developed a five-factor Lifestyle Index assessing physical activity, BMI, smoking, sleep quality, and sexual satisfaction in 312 Swiss adults aged 35 to 65 years. Higher scores were modestly associated with younger bio-functional age, suggesting a relationship between combined lifestyle patterns and functional health, although the findings cannot establish causation.

19 Oct 2026