Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Causes of Depression

5 Facts You May Not Know About Depression

Antidepressants and Weight Changes

Depression Diagnosis

Symptoms of Depression

Prisoner Depression and Low Mood

Depression and Sleep Length

How Does Your Diet Affect Depression?

Depression in children

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Ghrelin and Depression

See more featured articles »

Contributing Factors to Post-Adoption Depression

Situational Depression: Symptoms, Causes, Treatments

Treatment Options for Children with Depression

Link Between Chronic Illness and Depression

Supporting Children with Mental Health Disorders

Intrusive Thoughts and Depression

Genes and Depression

How is Depression in Children Diagnosed?

Food Insecurity and Depression

How Can I Tell if My Child is Depressed?

Can Depression and Anxiety Occur Together?

Treatment of Depression

Latest Depression News and Research

Portrayal of lorazepam use inTV series associated with increased online searches for the drug

In season three of the hit television series The White Lotus, the character Victoria Ratliff takes the prescription anti-anxiety medication lorazepam to help with her social anxiety and inability to sleep.

14 Nov 2025

New technique revolutionizes the design of drugs that target ion channels

An international team involving the Institute of Chemical Research, a joint centre of the University of Seville and the Spanish National Research Council, has developed a new technique that will accelerate the design of drugs that target ion channels, a type of cell membrane protein involved in numerous diseases, ranging from psychiatric disorders to various types of cancer.

14 Nov 2025

Hyperemesis gravidarum linked to depression in pregnant women

A recent study conducted at the University of Turku in Finland showed that hyperemesis gravidarum, a severe form of nausea that occurs during pregnancy, is linked to depression.

14 Nov 2025

Mental navigation framework helps people change pathological thinking

The stereotypical image of psychotherapy shows a patient lying on a couch, exploring their deepest traumas. This leads to awareness of unconscious habits, thoughts, and drives and has long been a cornerstone of psychotherapy.

14 Nov 2025

ICE crackdown heightens barriers for immigrant domestic violence victims

The immigrant from India believed her husband when he said that if she wasn't gone by the time he got to their Georgia home in 10 minutes, he would kill her.

13 Nov 2025

Study reveals long-term struggles after Stevens-Johnson syndrome and toxic epidermal necrolysis

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) survivors encounter rare, life-threatening drug reactions and years of physical, emotional and social consequences long after leaving the hospital, according to a study published today in JAMA Dermatology.

12 Nov 2025

Income and social disparities found to influence dementia risk factors

People with lower incomes and people from racial and ethnic historically underrepresented groups in clinical studies are more likely to have modifiable risk factors for dementia, factors that could be changed to lower their risk, according to a study published November 12, 2025, in Neurology, the medical journal of the American Academy of Neurology.

12 Nov 2025

National initiative helps reduce missed radiation appointments for cancer patients

A national quality improvement program led by the American College of Surgeons (ACS) found that transportation barriers and illness are among the top reasons cancer patients miss critical radiation therapy appointments - and that providing hospitals and patients with structured support can reduce missed appointments by up to 40%.

11 Nov 2025

The caffeine conundrum in rapid depression treatments

Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic dissection of rapid antidepressant action identifies adenosine as the critical mediator, yet adenosine receptors are the primary target of caffeine, the world's most widely consumed psychoactive substance.

11 Nov 2025

Shared genetic roots connect neurological and psychiatric disorders

In a groundbreaking study, researchers from the Centre for Precision Psychiatry at the University of Oslo and Oslo University Hospital have discovered extensive genetic links between neurological disorders like migraine, stroke and epilepsy, and psychiatric illnesses such as schizophrenia and depression.

11 Nov 2025

Preclinical study reveals dampened neuronal activity in alcohol-exposed mice

A psychedelic found in mushrooms is emerging as a potential treatment for alcohol use disorders. This possibility is due to a compound the body converts the psychedelic into called psilocin, but psilocin's mechanisms remain unclear.

11 Nov 2025

Listening to slow-tempo music may boost sleep quality for people over 50

Music therapy significantly improves sleep quality in adults aged 50 and above, showing a moderate-to-large effect compared with control conditions. However, high heterogeneity and methodological weaknesses mean the evidence remains of very low certainty and requires confirmation in larger, standardized trials.

10 Nov 2025

One concussion can raise your car crash risk by nearly 50%

Research shows that concussions elevate the risk of motor vehicle crashes, particularly in the weeks following injury, necessitating enhanced safety measures.

10 Nov 2025

Hypertensive disorders of pregnancy linked to increased risk of cardiovascular complications

A new study from researchers at Intermountain Health reveals that hypertensive disorders of pregnancy (HDP) significantly increase the risk of cardiovascular complications - including heart attack, stroke, heart failure, and death - within five years of giving birth.

10 Nov 2025

How modern habits are reshaping the Mediterranean diet for the worse

Nearly all children and adolescents in five Mediterranean countries consume unhealthy ultra-processed foods daily, according to the DELICIOUS Project. The study links higher intake to obesity, older age, screen time, eating out, and exposure to food advertising.

9 Nov 2025

Digital biomarkers revolutionize early diagnosis of endometriosis and pelvic conditions

For years, conversations around hormonal and pelvic health have been overshadowed by stigma, silence, and misunderstanding. Millions of women have endured pain without answers, suffering in silence. But change is coming

7 Nov 2025

Study highlights growing mental health concerns among U.S. international student population

Despite international students in U.S. higher education facing significant mental health challenges, national patterns of anxiety, depression, suicidal ideation, and mental health service use among this group remain poorly understood.

7 Nov 2025

Adults diagnosed with concussion face elevated risk of a traffic crash

Adults diagnosed with a concussion may be at about 50 per cent higher risk of a subsequent traffic crash, finds a new study from researchers at ICES and Sunnybrook Research Institute.

6 Nov 2025

Studies reveal how hereditary angioedema disrupts the lives of children and families

Two new studies being presented at the 2025 American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Orlando shed light on how hereditary angioedema (HAE) – a rare, potentially life-threatening disease which causes unpredictable swelling – profoundly affects the daily lives, emotional wellbeing, and medical experiences of young patients and their caregivers.

6 Nov 2025

Can creatine help with depression? New review says results are inconclusive

Creatine supplementation may modestly reduce depressive symptoms, but the effect is small, uncertain, and likely influenced by study bias. The evidence remains of very low quality, highlighting the need for larger, well-designed clinical trials.

6 Nov 2025