Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Prisoner Depression and Low Mood

Genes and Depression

5 Facts You May Not Know About Depression

Can Depression and Anxiety Occur Together?

Contributing Factors to Post-Adoption Depression

Treatment of Depression

Food Insecurity and Depression

Depression and Sleep Length

Supporting Children with Mental Health Disorders

Antidepressants and Weight Changes

Link Between Chronic Illness and Depression

See more featured articles »

How Can I Tell if My Child is Depressed?

Causes of Depression

Ghrelin and Depression

How Does Your Diet Affect Depression?

Treatment Options for Children with Depression

Depression in children

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

How is Depression in Children Diagnosed?

Depression Diagnosis

Situational Depression: Symptoms, Causes, Treatments

Intrusive Thoughts and Depression

Symptoms of Depression

Latest Depression News and Research

High levels of gut bacterial toxin linked to increased lupus nephritis risk

The body's immune reaction to increased levels of a toxic molecule, part of a bacterial species in the human gut, may reveal who is most at risk of developing lupus nephritis, according to a new study led by NYU Langone Health.

23 Apr 2026

Study links ADHD-related traits to increased chronic pain severity

A new study, led by researchers from the University of Tokyo, involving nearly 1,000 patients in Japan suggests that attention deficit hyperactivity disorder (ADHD)-related traits may be associated with and may contribute to chronic pain.

23 Apr 2026

Can exercise or ibuprofen fight chemo brain?

This study suggests exercise can mitigate cancer-related cognitive impairment, but combining it with ibuprofen offers no additional cognitive benefits.

23 Apr 2026

Sleep apnea more common in former football players than previously recognized

New research led by investigators at Vanderbilt Health and the Football Players Health Study at Harvard University suggests that sleep apnea may be far more common - and more clinically significant - among former professional football players than previously recognized.

22 Apr 2026

Rural and urban children face distinct mental health challenges

A study in Pediatric Investigation found that rural and urban children and adolescents tend to experience different mental health issues, with those living in the country showing more emotional problems and those in the city demonstrating more behavioral issues.

22 Apr 2026

Survey of families suggests high risks for electroconvulsive therapy

Electroconvulsive therapy (ECT), which involves passing electricity through the brain under general anesthesia to cause a seizure, usually between six and twelve times, is used to varying degrees around the world for patients with depression and other mental conditions.

22 Apr 2026

Autism risk rises with multiple medications taken during pregnancy

A study links maternal use of cholesterol-inhibiting medications during pregnancy to increased autism risk in children, urging caution in prescribing practices.

22 Apr 2026

Simple chair-rise test signals future health risks in seniors

How easily older adults can stand up from a chair may be a telling indicator of their overall quality of life.

21 Apr 2026

Bullying and social policies worsen mental health in gender-diverse teens

Gender-diverse adolescents who experience bullying and live in states with persistently unsupportive gender identity laws are significantly more likely to suffer escalating psychological distress compared to their peers, according to new research by UCLA Health.

21 Apr 2026

New guideline recommends combined therapies for chronic insomnia treatment

A new clinical practice guideline from the American Academy of Sleep Medicine provides evidence‑based recommendations on the combined use of behavioral‑psychological and pharmacological therapies to treat chronic insomnia disorder in adults.

21 Apr 2026

Study links cognitive worries in Parkinson’s to anxiety and depression

For many individuals living with Parkinson's disease and those in its "prodromal" or early stages before movement impairment, there is a distressing gap between how they feel their brain is working and what clinical tests show.

21 Apr 2026

Morning naps may flag higher mortality risk in older adults

Older adults who took longer and more frequent daytime naps, especially in the morning, had a higher risk of all-cause mortality in this prospective cohort study using actigraphy-based nap tracking. Variability in nap duration from day to day was not associated with mortality after full adjustment.

21 Apr 2026

Gut microbiome clues may help spot Parkinson’s disease in its earliest phase

Researchers found that a Parkinson’s disease-related gut microbiome pattern appears not only in people with diagnosed Parkinson’s, but also in some non-manifesting GBA1 variant carriers and a subset of healthy individuals. The findings suggest that gut microbiome changes may help flag people who are closer to Parkinson’s disease development, although longitudinal studies are still needed to confirm predictive value.

21 Apr 2026

Supportive relationships in childhood help buffer the long-term health effects of abuse

A consistent, caring adult during childhood can make a profound difference for child survivors of physical or sexual abuse.

21 Apr 2026

Coffee impacts the gut-brain axis to improve mood and stress

New research from APC Microbiome Ireland, a world leading research centre at University College Cork, has comprehensively explored the mechanisms behind coffee's positive effects on the gut-brain axis for the first time.

21 Apr 2026

Last patient has completed AlzeCure's Phase Ib clinical study with NeuroRestore ACD856

AlzeCure Pharma AB (publ), a biotech company that develops candidate drugs for diseases affecting the nervous system, focusing on Alzheimer's disease and pain, today announced that the last patient’s last visit (LPLV) has now occurred in the ongoing Phase Ib clinical trial of ACD856, the lead drug candidate within the NeuroRestore platform, which is being developed for Alzheimer’s disease and other indications.

From AlzeCure Pharma AB 21 Apr 2026

Brain organoids may guide Alzheimer’s diagnosis and treatment

Scientists from Johns Hopkins Medicine report new evidence that clusters of brain tissue derived from the cells of patients with Alzheimer's disease may be used to evaluate how certain patients with the neurodegenerative condition may respond to drugs commonly prescribed to treat psychiatric symptoms of the disorder.

20 Apr 2026

Serotonin may worsen tinnitus symptoms, mice study finds

The same neurotransmitter commonly leveraged to relieve symptoms of depression and anxiety also may exacerbate a vexing condition known as tinnitus, according to new research published in the Proceedings of the National Academy of Sciences.

20 Apr 2026

Your new therapist: Chatty, leaky, and hardly human

Vince Lahey of Carefree, Arizona, embraces chatbots. From Big Tech products to "shady" ones, they offer "someone that I could share more secrets with than my therapist."

17 Apr 2026

Women using GLP-1 drugs face higher weight loss stigma

In a new study exploring stigma associated with the use of GLP-1 drugs for weight loss, women who lost weight using GLP-1 medications were judged more harshly than those who lost weight through diet and exercise, with negative reactions driven largely by beliefs that medication-assisted weight loss is a "shortcut."

17 Apr 2026