Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

How is Depression in Children Diagnosed?

Symptoms of Depression

Treatment Options for Children with Depression

Can Depression and Anxiety Occur Together?

Depression and Sleep Length

How Does Your Diet Affect Depression?

Treatment of Depression

Situational Depression: Symptoms, Causes, Treatments

Food Insecurity and Depression

Contributing Factors to Post-Adoption Depression

Link Between Chronic Illness and Depression

See more featured articles »

Supporting Children with Mental Health Disorders

Intrusive Thoughts and Depression

Prisoner Depression and Low Mood

Depression in children

How Can I Tell if My Child is Depressed?

5 Facts You May Not Know About Depression

Ghrelin and Depression

Causes of Depression

Genes and Depression

Antidepressants and Weight Changes

Depression Diagnosis

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Latest Depression News and Research

Medical societies release landmark framework redefining women's heart health

Today, the American Heart Association, American Academy of Pediatrics, American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine released a landmark publication that redefines heart health in girls and women.

26 Oct 2026

Physical activity may help lower genetic risk of depression in adults

Adding physical activity to a daily routine may seem like a simple step for better health, but research from Kansas State University suggests it could be especially beneficial for individuals with a genetic predisposition to depression, potentially helping reduce their risk and ease their symptom burden.

26 Oct 2026

New report urges unified lifecycle approach to women's heart health

A new approach to women's heart health may offer them a lifetime of opportunities. A trio of scientific papers, published today in the journal Circulation, spells out how fluctuating hormones, mental health and well-being, the heart and the brain are linked and how those connections need to be a routine part of care from a young age.

26 Oct 2026

Understanding the symptoms and treatments of pelvic organ prolapse

The pelvic floor is a layer of muscles and connective tissues that supports the uterus, bladder, urethra, vagina and rectum. The pelvic floor supports the organs in your pelvis from underneath, almost like a hammock.

26 Oct 2026

Women in perimenopause report more anxiety than other menopausal groups

Researchers reviewed 21 studies involving 24,523 women and found that perimenopausal and postmenopausal women had higher odds of reporting anxiety symptoms than premenopausal women. Their meta-analysis of 15 studies found the highest odds during perimenopause, but the cross-sectional evidence cannot establish that menopause causes anxiety.

25 Oct 2026

Kidney Week 2026 features late-breaking clinical trials in kidney care

The American Society of Nephrology, has selected the following late breaking clinical trials to be presented in-person at Kidney Week 2026 October 22–25.

24 Oct 2026

LGBTQ+ college students facing discrimination report higher mental health risks

LGBTQ+ college students who experience discrimination are significantly more likely to experience depression, anxiety, suicidal thoughts, and avoid needed health care, according to a new national study by Columbia University Mailman School of Public Health, Boston University School of Public Health and Harvard Pilgrim Health Care Institute.

23 Oct 2026

Low-power implantable neural chip tracks communication across brain regions

Deep brain stimulation (DBS) is a therapeutic technique that delivers electrical pulses to specific areas of the brain via an implant to modulate neural activity.

23 Oct 2026

Psilocybin reshapes brain connections through distinct cellular pathways

A new study led by researchers at the University of California, Santa Cruz, reveals how psilocybin, the psychoactive compound in "magic mushrooms," reshapes neural connections in the brain.

22 Oct 2026

Australian study highlights delayed diagnosis in postpartum psychosis care

Women with postpartum psychosis are making repeated pleas for help before receiving a diagnosis, with the first Australian study of their help-seeking experiences finding many contacted health services an average of seven times before getting the care they needed.

22 Oct 2026

Depression profile linked to disrupted sleep and poorer treatment responses

This study uncovers a circadian depression subtype, revealing links between sleep patterns, symptom severity, and antidepressant response in a large cohort.

22 Oct 2026

LSD speeds up brain waves and increases neural complexity, study finds

First synthesized in a laboratory in 1938 by the Swiss chemist Albert Hofmann, lysergic acid diethylamide, better known by its acronym LSD, is one of the most potent and most extensively studied psychedelics.

22 Oct 2026

New study explores psychedelic therapy for co-occurring cocaine addiction and depression

A team of UTHealth Houston researchers has been awarded a five-year, $3.4 million grant to study whether psilocybin-assisted therapy is a viable treatment option for individuals with co-occurring cocaine use disorder and major depressive disorder.

22 Oct 2026

Digital mindfulness program cuts depression relapse risk in mothers by 26%

A free, online program developed by University of Colorado Boulder researchers has been shown to reduce risk of depression relapse by double digits among new moms and moms-to-be with a history of depression.

22 Oct 2026

Accelerated TMS cuts depression treatment time from six weeks to three

Transcranial magnetic stimulation (TMS) has proved to be a very effective non-invasive treatment for people with severe depression who have not had success with medication. But traditional TMS has one significant drawback: time.

21 Oct 2026

AI-powered eye tracking could personalize virtual reality therapy for chronic pain

Combining artificial intelligence (AI) with eye tracking in virtual reality could one day help personalize treatment for millions living with chronic pain, according to world-first research from the University of East Anglia.

21 Oct 2026

Japanese study links postpartum depression to mother-infant bonding difficulties

A Japanese study found that higher postpartum depression scores were associated with greater mother–infant bonding difficulties.

21 Oct 2026

Marital breakups can impact vulnerability decades later in old age

Marital breakups do not only have immediate consequences, typical of the moment when cohabitation ends.

21 Oct 2026

Postpartum psychosis symptoms frequently dismissed as standard baby blues

In an interview-based study in the Journal of Advanced Nursing including 15 Australian women diagnosed with postpartum psychosis over the past 10 years, women reported that they made multiple attempts to seek medical help and support, yet they encountered delayed recognition, inadequate assessment and, at times, dismissal or minimization of their concerns.

21 Oct 2026

Oxaloacetate supplement may help reduce chemo brain in breast cancer survivors

A new study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that a nutritional supplement containing oxaloacetate, a molecule naturally found in the body that helps cells produce energy, may help improve cognitive function and reduce the fatigue experienced by some breast cancer survivors following treatment.

21 Oct 2026