Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Causes of Depression

How Does Your Diet Affect Depression?

Depression Diagnosis

Genes and Depression

Symptoms of Depression

Treatment of Depression

Depression in children

How Can I Tell if My Child is Depressed?

How is Depression in Children Diagnosed?

Treatment Options for Children with Depression

Contributing Factors to Post-Adoption Depression

See more featured articles »

Ghrelin and Depression

Prisoner Depression and Low Mood

Intrusive Thoughts and Depression

Supporting Children with Mental Health Disorders

Depression and Sleep Length

Link Between Chronic Illness and Depression

Situational Depression: Symptoms, Causes, Treatments

Can Depression and Anxiety Occur Together?

Antidepressants and Weight Changes

Food Insecurity and Depression

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

5 Facts You May Not Know About Depression

Latest Depression News and Research

Study finds successful treatment of childhood obesity lowers long-term health risks

Effective treatment of childhood obesity significantly lowers long-term health risks, including type 2 diabetes and hypertension, promoting better adult health.

24 Jan 2025

School-based program cuts depression and anxiety in newcomer students

The first randomized control trial of the school-based intervention called Supporting Transition Resilience of Newcomer Groups (STRONG) shows significant reductions in depression, anxiety and behavior problems among refugee and immigrant students.

23 Jan 2025

Uncertainty surrounds effects of puberty blockers and hormone therapy for gender dysphoria

Major uncertainties remain about the impact of puberty blockers and gender affirming hormone therapy on children and young people with gender related distress (gender dysphoria), making it impossible to determine conclusively whether they help or harm, find two pooled data analyses of the available evidence, published online in the Archives of Disease in Childhood.

23 Jan 2025

Adverse childhood experiences linked to defensive gun use in adulthood

Researchers at Rutgers University have found that adverse childhood experiences can make people more sensitive to potential threats from others, which in turn increases their risk of engaging in defensive gun use in adulthood.

23 Jan 2025

Parental divorce in childhood tied to 61% higher stroke risk in older adults

Experiencing parental divorce in childhood is associated with a significantly higher risk of stroke in older adulthood, even after accounting for key risk factors such as income, depression, and diabetes.

23 Jan 2025

Two-thirds of people with post-COVID-19 syndrome experience long-term effects

Two-thirds of people with post-COVID-19 syndrome have persistent, objective symptoms – including reduced physical exercise capacity and reduced cognitive test performances – for a year or more, with no major changes in symptom clusters during the second year of their illness, according to a new study published January 23rd in the open-access journal PLOS Medicine by Winfried Kern of Freiburg University, Germany, and colleagues.

23 Jan 2025

New genomic insights could transform bipolar disorder treatment

Study published in Nature identifies nearly 300 genomic regions associated with bipolar disorder, and 36 key genes involved in the disease.

23 Jan 2025

What causes behavioral side effects in popular weight loss drugs?

The study of GLP1R variants shows associations with cardiometabolic traits and behavioral changes, highlighting indirect effects of GLP1RA on mental health.

23 Jan 2025

Multiple sclerosis linked to increased risk of perinatal mental illness

People with multiple sclerosis (MS) face a significantly higher risk of perinatal mental illness compared to those with other chronic conditions, according to a new study analyzing over 890,000 births in Ontario.

23 Jan 2025

Study links PTSD and anxiety to lower ovarian reserve in women firefighters

A new study led by University of Arizona Mel and Enid Zuckerman College of Public Health researchers in collaboration with fire service partners and other researchers around the country through the Fire Fighter Cancer Cohort Study showed that post-traumatic stress disorder and anxiety are associated with lower levels of anti-Müllerian hormone, a marker of ovarian reserve, among women firefighters.

22 Jan 2025

Researchers construct a detailed structural map of GABAA receptors in the human brain

Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other.

22 Jan 2025

Brain signals involved in reward learning may hold key to personalized depression treatments

In a study in the Journal of Affective Disorders, Fralin Biomedical Research Institute scientists Pearl Chiu and Brooks Casas investigate how brain signals involved in reward learning might help personalize depression treatment.

22 Jan 2025

Study links parental divorce to increased stroke risk in adult children

A recent study by researchers from the University of Toronto, Tyndale University and the University of Texas at Arlington found that older adults are at greater risk of having a stroke if they experienced their parents divorcing during childhood.

22 Jan 2025

Social but lonely? The emotional challenges of highly sensitive people

Highly Sensitive Persons (HSPs) experience greater emotional loneliness due to their deep need for meaningful relationships, but their social interactions are similar to the general population.

22 Jan 2025

Mental health risks higher for pregnant people with MS

Pregnant people with multiple sclerosis (MS) have a higher chance of experiencing mental illness both during their pregnancy and in the first years after they give birth than those without MS, according to a study published in the January 22, 2025 online issue of Neurology®, the medical journal of the American Academy of Neurology.

22 Jan 2025

Social interventions could lead to major drop in national HIV incidence

Researchers at the University of Massachusetts Amherst have quantified the impacts of a constellation of social factors on the spread of HIV.

22 Jan 2025

Long-covid patients are frustrated that federal research hasn’t found new treatments

Erica Hayes, 40, has not felt healthy since November 2020 when she first fell ill with covid.

22 Jan 2025

Innovative research links biometric data to mood prediction in shift workers

The CORONA virus pandemic also brought about a pandemic of mental illness. Approximately one billion people worldwide suffer from various psychiatric conditions. Korea is one of more serious cases, with approximately 1.8 million patients exhibiting depression and anxiety disorders, and the total number of patients with clinical mental diseases has increased by 37% in five years to approximately 4.65 million.

22 Jan 2025

OncoAssure announces clinical validation of prostate cancer test

OncoAssure Ltd, an Irish medical diagnostic company, today announced the publication of new data, in the British Journal of Urology International Compass (BJUI Compass), which demonstrates the clinical validation of OncoAssure Prostate, a novel biopsy test which provides improved estimation of a patient’s risk of prostate cancer recurrence and allows for optimal treatment selection.

21 Jan 2025

Pregnant women often left out of drug trials, study finds

A new study by researchers from the Brown University School of Public Health found that pregnant women are regularly excluded from clinical drug trials that test for safety, raising concerns for the efficacy of these medications for maternal and child health.

21 Jan 2025