Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Antidepressants and Weight Changes

Food Insecurity and Depression

Situational Depression: Symptoms, Causes, Treatments

Intrusive Thoughts and Depression

Symptoms of Depression

How Does Your Diet Affect Depression?

Can Depression and Anxiety Occur Together?

Depression in children

How is Depression in Children Diagnosed?

Prisoner Depression and Low Mood

Contributing Factors to Post-Adoption Depression

See more featured articles »

5 Facts You May Not Know About Depression

Ghrelin and Depression

Genes and Depression

Link Between Chronic Illness and Depression

Treatment of Depression

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Depression and Sleep Length

Treatment Options for Children with Depression

Causes of Depression

Supporting Children with Mental Health Disorders

How Can I Tell if My Child is Depressed?

Depression Diagnosis

Latest Depression News and Research

Paternal postpartum depression affects more fathers than widely recognized

Postpartum depression in mothers is a widely recognized condition that affects 1 in 7 women. But less known is that 1 in 10 new fathers also experience depression.

8 Jul 2026

Trial shows potential benefit of ketogenic diet for treating psychotic disorders

Published today in Schizophrenia Bulletin, a first-of-its-kind randomized controlled trial (RCT) from researchers at the University of California, San Francisco (UCSF), and funded in part by the National Institute of Mental Health (NIMH), adds to growing literature on the potential benefit of a ketogenic diet for treating psychotic disorders.

8 Jul 2026

New framework aligns neural implants with user's needs

Gabriel Lázaro-Muñoz, PhD, JD, and Amanda R. Merner, PhD, of the Health Technology Performance Lab within the Mass General Brigham Neuroscience Institute, are the authors of a paper published in The American Journal of Psychiatry, "Implantable Neuromodulation Devices in Psychiatry: Human Fidelity and Implementation Challenges."

8 Jul 2026

Review highlights pregnancy and miscarriage rates among transmasculine people

A recent review of published research provides some evidence that a small but noteworthy minority of transmasculine people (trans, nonbinary, and other gender expansive people who were assigned female at birth) have pregnancies (6%–9%) and children (4%–9%), including after transition.

8 Jul 2026

Most hospital readmissions after heart failure are not heart-related

A study reveals that non-cardiovascular medications increase hospital readmission risks in heart failure patients, highlighting the need for better management.

8 Jul 2026

Sleep apnea and erectile dysfunction share a stronger link than expected

A systematic review and meta-analysis of 8 observational studies found that greater obstructive sleep apnea severity was associated with poorer erectile function, with higher AHI linked to lower IIEF scores and higher minimum oxygen saturation linked to higher IIEF scores. The authors caution that the evidence remains observational, heterogeneous, and low certainty, so the findings support targeted screening rather than proving causality.

8 Jul 2026

Early menopause remains common among women in low and middle income countries

Early menopause affects 1 in 14 women aged 30 to 49 living in low and middle income countries, finds a pooled data analysis of its prevalence in 44 nations published in the open access journal BMJ Global Health.

7 Jul 2026

New review shows why antidepressants often fail in Alzheimer’s and Parkinson’s depression

A Molecular Psychiatry review shows that depression in Alzheimer’s and Parkinson’s disease may reflect disease-specific molecular, neurotransmitter, inflammatory, and circuit-level disruptions rather than standard depression biology alone. It argues that broad antidepressants often show limited efficacy in these patients and that future trials should use biomarkers, neuroimaging, and symptom profiling to guide targeted treatments.

7 Jul 2026

Researchers identify brain circuits responsible for triggering OCD symptoms

Most of the time, the origin of obsessive-compulsive disorder (OCD) is unknown, but in some rare cases, it starts after a brain injury, such as a stroke or a tumor.

7 Jul 2026

Study offers insight into how long-term inflammation may contribute to cognitive decline

The King's College London study, published in Nature Communications, offers insight into how long-term inflammation may contribute to cognitive decline in disorders such as Alzheimer's disease, aging, depression, and the lingering neurological effects of viral infections.

7 Jul 2026

Psychiatry may be moving closer to precision medicine

For decades, treating depression has largely involved a difficult form of medical guesswork: prescribing one antidepressant after another in hopes that one will eventually help.

6 Jul 2026

Rumination carries anxiety into deeper distress for caregivers of dementia patients

A new study from Virginia Tech suggests patterns of repetitive negative thinking explain how anxiety develops into deeper stress for caregivers of people living with dementia, and that mindfulness training may help identify and interrupt that progression.

6 Jul 2026

Lifelong violence against women linked to significantly earlier menopause

The research, published in the journal Maturitas, links trauma experienced to the onset of the menopause up to 20 months earlier and an increase in hot flushes, depression and cardiometabolic health problems.

6 Jul 2026

Reduced sunshine linked to higher demand for mental health care

The study highlights the relationship between weather and mental health care use, suggesting routine weather patterns could forecast service demand effectively.

3 Jul 2026

European project explores how gut microbiome, dietary and lifestyle factors interact with mental health

Mental health conditions such as anxiety and depression affect millions of people across Europe and are increasingly recognised as closely linked to diet, nutrition, social inequalities and broader lifestyle factors.

2 Jul 2026

Lung tumors hijack nervous system to drive cancer-related cachexia

According to the Cleveland Clinic, a quarter of cancer deaths can be attributed to one source: cachexia. Cachexia is a syndrome that accompanies underlying chronic illness and causes unwanted muscle and fat loss, reducing quality of life and sometimes even limiting treatment options.

2 Jul 2026