Dermatology News and Research

Latest Dermatology News and Research

LCZ696 could be of PARAMOUNT importance in heart failure

The first-in-class angiotensin receptor neprilysin inhibitor LCZ696 could improve treatment of heart failure, report researchers who conducted a phase II trial of the drug and found it had superior results to an alternative therapy already in use.

31 Aug 2012

Tunes and T-shirts for cardiac rehabilitation

Two studies presented at the European Society of Cardiology Congress in Munich, Germany, showed how researchers are developing innovative approaches to help patients get the most out of cardiac rehabilitation.

31 Aug 2012

Early European TAVI registry data unveiled

The 1-month follow-up results of the Transcatheter Valve Treatment Sentinel Pilot Registry have provided data on factors associated with transcatheter aortic valve implantation, as well as short term outcomes, in Europe.

30 Aug 2012

Dabigatran exposure may RE-LY on genetics

Researchers have found that variants in the ABCB1 and CES1 genes are associated with increased dabigatran plasma levels in patients taking the oral anticoagulant.

30 Aug 2012

Long-term cardiac impact of Japan quake revealed

The earthquake and tsunami that devastated parts of eastern Japan in 2011 led to a significantly increased weekly occurrence of cardiovascular disease in the months after the event, study findings show.

29 Aug 2012

Tunes and T-shirts for cardiac rehabilitation

29 Aug 2012

PROTECT: Still no clear winner in the battle of the stent generations

Three-year rates of stent thrombosis with zotarolimus- and sirolimus-eluting stents are low and comparable, show results of the PROTECT trial.

29 Aug 2012

FAST-MI highlights young women at risk for heart disease

An analysis of four French registries has shown a dramatic drop in ST-segment-elevation myocardial infarction mortality from 1995 to 2010, accompanied by a significant change in patient characteristics.

29 Aug 2012

Merz acquires CUVPOSA oral solution to treat children with cerebral palsy

Merz, Inc. today announced the acquisition of CUVPOSA (glycopyrrolate) oral solution for pediatric chronic severe drooling associated with neurologic conditions such as cerebral palsy.

27 Aug 2012

ALDH enzyme marks melanoma stem cells

Cancer stem cells are defined by three abilities: differentiation, self-renewal and their ability to seed a tumor. These stem cells resist chemotherapy and many researchers posit their role in relapse. A University of Colorado Cancer Center study recently published in the journal Stem Cells, shows that melanoma cells with these abilities are marked by the enzyme ALDH, and imagines new therapies to target high-ALDH cells, potentially weeding the body of these most dangerous cancer creators.

24 Aug 2012

UK carotid endarterectomy results revealed

Round 4 of the UK Carotid Endarterectomy Audit, organized by the Royal College of Physicians, has revealed that the average delay from stroke or transient ischemic attack symptom onset to surgery is shortening.

23 Aug 2012

Downward trend for heart failure in Canada

The incidence of heart failure in Ontario, Canada, substantially decreased between 1997 and 2008, a study suggests.

22 Aug 2012

Ventricular factors linked to early and late post-cardiac surgery mortality

Increased left ventricular mass index predicts perioperative mortality in patients undergoing cardiac surgery, while a decreased fractional area of contraction in the left ventricle is linked to 1-year mortality, US scientists have found.

22 Aug 2012

Evidence stacks up against bisphenol A

High levels of urinary bisphenol A may be linked to severe coronary artery stenosis, report researchers in PLoS One.

22 Aug 2012

Highly sensitive troponin assay shortens heart attack diagnosis

An algorithm that incorporates high-sensitivity cardiac troponin could allow accurate rule-in and rule-out of patients with acute chest pain within 1 hour of presentation, a study shows.

21 Aug 2012

CKD may raise stroke, bleeding risk in AF patients

Danish study results show that the presence of chronic kidney disease appears to raise the risk for stroke, systemic thromboembolism, and bleeding among patients with atrial fibrillation.

21 Aug 2012

CHD patients do not need to rule out high-intensity exercise

Findings from a retrospective study show that patients with coronary heart disease who engage in high-intensity exercise have a similarly low risk for a cardiovascular event as those engaging in moderate-intensity exercise.

21 Aug 2012

Gene therapy applied to peripheral arterial disease

Hepatocyte growth factor gene therapy could be used to treat patients with severe peripheral arterial disease, suggest results of a phase I clinical trial.

21 Aug 2012

Molecular Partners, Allergan to develop and commercialize DARPins against ophthalmic diseases

Allergan, Inc. and Molecular Partners AG today announced that they have significantly expanded their existing relationship by entering into two separate agreements to discover, develop, and commercialize proprietary therapeutic DARPin products for the treatment of serious ophthalmic diseases.

21 Aug 2012

Portable Micro-Plasma Device may help repair skin after laser surgery

A National Cheng Kung University (NCKU) research team has designed a Portable Micro-Plasma Device (PMPD) that may be the ultimate solution to repairing the skin after laser surgery.

21 Aug 2012