Diarrhea News and Research

Latest Diarrhea News and Research

Researchers find new fusion protein for E.coli bacterium vaccine development

South Dakota State University research is exploring a "fusion strategy" for making improved vaccines to protect pigs and humans against some strains of E. coli.

2 Sep 2010

Prometheus launches Crohn's Prognostic test

Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, today announced the commercial launch of its proprietary PROMETHEUS® Crohn's Prognostic test. This novel and unique diagnostic represents a significant advance in the Prometheus Inflammatory Bowel Disease (IBD) franchise of diagnostic and prognostic tests, and complements the market-leading PROMETHEUS® IBD Serology 7.

2 Sep 2010

Death toll expected to rise as flooding subsides in some parts of Pakistan

Pakistani government officials say the death toll from the country's flooding stands at more than 1,600 and it could rise significantly as flood waters recede and more bodies are identified, CNN reports (8/28). "There is no official estimate of the number of missing because mass displacements have made accounting for them almost impossible," according to Reuters (Haider, 8/29).

31 Aug 2010

Ten million face hunger in Central Africa; Niger flooding exacerbates food shortage, leaves 200,000 homeless

Flash floods have "worsened an already chronic humanitarian crisis caused by drought" in central Africa where aid agencies have warned that "10 million people are already facing severe food shortages, particularly in the landlocked countries of Chad and Niger, after a drought led to the failure of last year's crops," the Independent reports.

31 Aug 2010

Tapentadol ER improves average intensity of chronic osteoarthritis knee pain: Study

Phase 3 safety and efficacy data comparing tapentadol extended release (ER) tablets, an investigational pain medication, to placebo in patients with moderate to severe chronic osteoarthritis knee pain have been published by Clinical Drug Investigation.

31 Aug 2010

FDA approves additional strengths of SOLODYN for inflammatory lesions treatment

Medicis today announced that the U.S. Food and Drug Administration (FDA) has approved additional strengths of SOLODYN (minocycline HCl, USP) Extended Release Tablets in 55 mg, 80 mg and 105 mg dosages for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 12 years of age and older.

30 Aug 2010

Santarus extends line of credit agreement maturation date to July 2013

Santarus, Inc., a specialty biopharmaceutical company, today announced that it has extended the maturity date of its $25 million revolving line of credit with Comerica Bank from July 11, 2011 to July 11, 2013.

30 Aug 2010

Researchers identify molecule to slow down dysfunctional immune response in hemorrhagic shock

Researchers have isolated a molecule, small enough to be used as a drug, that can shut down a dysfunctional immune response that causes deadly hemorrhagic shock, results in delayed death of heart attack patients, promotes rejection of transplanted organs and destroys joints in patients with rheumatoid arthritis, according to a paper published in Molecular Immunology.

27 Aug 2010

At least 3.5M Pakistanis have no access to clean water, raising risk for waterborne diseases

UNICEF estimates that about 3.5 million Pakistanis only have access to contaminated water, the U.N. Office for the Coordination of Humanitarian Affairs (OCHA) said on Wednesday in a statement, Bloomberg Businessweek reports. Approximately 2.5 million flood survivors now have access clean water (Gale, 8/26).

27 Aug 2010

FDA denies accelerated approval of Genentech's trastuzumab-DM1 (T-DM1) BLA for metastatic breast cancer

In its review of the BLA, the FDA stated the T-DM1 trials did not meet the standard for accelerated approval because all available treatment choices approved for metastatic breast cancer, regardless of HER2 status, had not been exhausted in the study population.

27 Aug 2010

U-M researchers explore prevention measures, treatments for C. difficile infection

Clostridium difficile, a wily, familiar bacterium, causes a growing number of serious infections in U.S. hospitals and nursing homes. With a $7.5 million, five-year award from the National Institutes of Health, University of Michigan researchers plan to discover what factors in the microbe and in patients make C. difficile a formidable, costly problem.

27 Aug 2010

Plantain and broccoli fiber help in Crohn’s disease: Study

New research suggests that plant fibers in plantains and broccoli can help prevent relapses of Crohn's disease. This disease is a long term disease of the gut that is characterized by inflammation of the lining of the digestive system, with symptoms including diarrhea and abdominal pain. Crohn's disease affects between 400,000 and 600,000 people in North America. Scientists believe that rise in processed food and decrease in fibers in diet could be a reason for rise of incidence of this disease.

25 Aug 2010

Diarrhea, skin diseases increase among children in flood-affected areas of Pakistan: Survey

World Vision says assessments conducted over the last few days near the towns of Muzaffar Garh and Kot Addo in Punjab paint a bleak picture of the impact of the flooding. The Christian humanitarian organization says its reports from Sukkur in the Sindh Province are equally dire. Contaminated water, cramped living conditions and a lack of sanitation are contributing to a rapid increase in cases of diarrhea and skin diseases in children.

25 Aug 2010

Celgene to enforce REVLIMID intellectual property rights following receipt of Paragraph IV notification letter

Celgene Corporation today announced that information was posted on the FDA Web site indicating that an Abbreviated New Drug Application (ANDA) has been received by the Office of Generic Drugs (OGD) containing a "Paragraph IV" patent certification, for REVLIMID (lenalidomide) 25 mg capsules. Celgene has not yet received the Paragraph IV notification letter identifying the filer.

25 Aug 2010

As flood waters spread, international aid for Pakistan tops $800M, foreign minister says

International donors have pledged more than $800 million to help Pakistan deal with severe flooding after the U.N. appealed for $460 million in aid, Shah Mahmood Qureshi, the country's foreign minister, said on Sunday, the Associated Press reports.

24 Aug 2010

EPA selects Precision Antibody to develop monoclonal antibodies for 'Crypto' intestinal parasite

Precision Antibody™ announced today its selection by the United States Environmental Protection Agency (EPA) to develop monoclonal antibodies to two species of Cryptosporidium, an intestinal parasite that has emerged over the past 20 years as one of the most common causes of waterborne illness in the United States.

24 Aug 2010

Pfizer reports Progression-Free survival in SUN 1087 combination trial of sunitinib with erlotinib for NSCLC

Pfizer Inc. announced today that the SUN 1087 trial of sunitinib in combination with erlotinib versus erlotinib demonstrated a statistically significant improvement in Progression-Free but not in Overall Survival in patients with previously treated advanced non-small cell lung cancer (NSCLC).

24 Aug 2010

Pfizer's Prevenar 13-valent pneumococcal conjugate vaccine receives WHO prequalification

The World Health Organization (WHO) has granted prequalification to Prevenar 13 (Pneumococcal polysaccharide conjugate vaccine [13-valent, adsorbed])for active immunization of infants and children from 6 weeks through five years of age against invasive disease, pneumonia and otitis media caused by the 13 pneumococcal serotypes (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) contained in the vaccine.

24 Aug 2010

Genzyme announces publication of phase 2 clinical trial results of eliglustat tartrate for Gaucher disease

Genzyme Corporation announced today that the two-year follow-up results from the phase 2 clinical trial of its investigational therapy known as eliglustat tartrate have been accepted for publication in the journal Blood. The results have been pre-published on the journal's website and are available to subscribers.

23 Aug 2010

Donors announce new pledges for Pakistan flood relief

The U.S. and other donor nations "significantly upped their pledges" of aid for the flooding in Pakistan during a U.N. General Assembly meeting on Thursday, in which the U.N. "appeared to [meet] its target of $460 million in immediate aid for flood-stricken Pakistan," the Associated Press reports.

21 Aug 2010

Diarrhea News and Research

Latest Diarrhea News and Research

Researchers find new fusion protein for E.coli bacterium vaccine development

Prometheus launches Crohn's Prognostic test

Death toll expected to rise as flooding subsides in some parts of Pakistan

Ten million face hunger in Central Africa; Niger flooding exacerbates food shortage, leaves 200,000 homeless

Tapentadol ER improves average intensity of chronic osteoarthritis knee pain: Study

FDA approves additional strengths of SOLODYN for inflammatory lesions treatment

Santarus extends line of credit agreement maturation date to July 2013

Researchers identify molecule to slow down dysfunctional immune response in hemorrhagic shock

At least 3.5M Pakistanis have no access to clean water, raising risk for waterborne diseases

FDA denies accelerated approval of Genentech's trastuzumab-DM1 (T-DM1) BLA for metastatic breast cancer

U-M researchers explore prevention measures, treatments for C. difficile infection

Plantain and broccoli fiber help in Crohn’s disease: Study

Diarrhea, skin diseases increase among children in flood-affected areas of Pakistan: Survey

Celgene to enforce REVLIMID intellectual property rights following receipt of Paragraph IV notification letter

As flood waters spread, international aid for Pakistan tops $800M, foreign minister says

EPA selects Precision Antibody to develop monoclonal antibodies for 'Crypto' intestinal parasite

Pfizer reports Progression-Free survival in SUN 1087 combination trial of sunitinib with erlotinib for NSCLC

Pfizer's Prevenar 13-valent pneumococcal conjugate vaccine receives WHO prequalification

Genzyme announces publication of phase 2 clinical trial results of eliglustat tartrate for Gaucher disease

Donors announce new pledges for Pakistan flood relief

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

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Diarrhea News and Research

Latest Diarrhea News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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