Diarrhea News and Research

Latest Diarrhea News and Research

Live oral Shigella vaccine licensed to PATH

The University of Maryland, Baltimore (UMB) has licensed a pediatric vaccine against Shigella bacteria to PATH, an international nonprofit group, to support clinical trials, with the goal of developing a vaccine suitable for children in resource-poor countries.

24 Nov 2008

Nplate receives positive opinion for marketing authorisation in Europe

Amgen has announced that the European Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion recommending marketing authorisation for Nplate (romiplostim) in the European Union (EU).

21 Nov 2008

Ortho Biotech submits NDA for Trabectedin in relapsed ovarian cancer

Ortho Biotech Products, L.P. has announced the submission of a new drug application (NDA) to the U.S. Food and Drug Administration (FDA) for trabectedin when administered in combination with DOXIL (doxorubicin HCI liposome injection) for the treatment of women with relapsed ovarian cancer (ROC).

20 Nov 2008

Gefitinib just as effective as chemotherapy for lung cancer

Gefitinib, also known as Iressa, the once-promising targeted therapy for the treatment of non-small cell lung cancer, has proven as effective as chemotherapy as a second-line therapy for the disease with far fewer side effects, according to an international Phase III clinical trial, led by researchers at The University of Texas M. D. Anderson Cancer Center.

20 Nov 2008

FDA strengthens safety of Sucraid (sacrosidase) oral solution

The U.S. Food and Drug Administration today issued an expedited approval of a supplemental application that allows for changes in the manufacturing of Sucraid (sacrosidase) Oral Solution.

20 Nov 2008

Bionovo to present phase 1B trial results of BZL101 in metastatic breast cancer

Bionovo, Inc. has announced the company will present results from the Phase 1B clinical trial of their lead drug candidate for advanced metastatic breast cancer, BZL101, at the Society for Integrative Oncology's Fifth International Conference in Atlanta, Georgia.

20 Nov 2008

Adalimumab therapy may reduce health-care costs for Crohn's disease patients

Inflammatory bowel disease (IBD) is a term that refers to both ulcerative colitis (UC) and Crohn's disease (CD).

12 Nov 2008

New report shows high Clostridium difficile infection rates in U.S. hospitals

Consumers Union called on hospitals today to take more aggressive steps to protect patients from Clostridium difficile (C.-diff.) infections in light of a new report showing that they are much more common than previous estimates had indicated. As the rate of hospital acquired C.-diff. infections has jumped in recent years, an increasing number of patients have developed antibiotic-resistant strains of the infection that are more difficult to treat and more deadly.

11 Nov 2008

Scientists create therapy programme to treat depression in women in developing countries

Although depression is a major health problem world-wide, experts say its impact is greatest in developing countries where 80% of the population live. Often there are no resources available to treat sufferers.

11 Nov 2008

Study improves recovery for mothers with depression

Scientists at the University of Liverpool have developed a therapy programme to treat depression in women in developing countries.

10 Nov 2008

VIA Pharmaceuticals announces results of phase 2 trials of VIA-2291 in cardiovascular disease

VIA Pharmaceuticals, Inc. has announced the results of two Phase 2 studies of its lead drug, VIA-2291.

10 Nov 2008

New report looks at weight-loss diets, eating plans and diet pills

Over-the-counter weight-loss pills are no quick fix to melt away extra pounds.

6 Nov 2008

10 symptoms that should never be ignored

Not every ache and pain merits a quick trip to the doctor -- but some do.

6 Nov 2008

Tibotec presents interim findings for TMC435, investigational hepatitis C treatment

New clinical data show antiviral activity of TMC435, an investigational protease inhibitor (PI) being developed by Tibotec BVBA for the treatment of chronic hepatitis C virus (HCV) infection.

4 Nov 2008

Phase 2 trial of treatment of C-difficile-associated diarrhea shows promise

Medarex, Inc. and The Massachusetts Biologic Laboratories (MBL) of the University of Massachusetts Medical School (UMMS) today announced that a Phase 2 trial of an anti- C. difficile antibody combination treatment in patients with C.

4 Nov 2008

Current hospital tests for Clostridium difficile not accurate enough

Current hospital tests for the bacterium Clostridium difficile (C difficile) are not accurate enough and a new two-stage process should be introduced to avoid misdiagnosis and its consequences.

2 Nov 2008

Rice can trigger a severe allergic reaction in babies

According to new research by Australian doctors, contrary to the current view of it as a hypo-allergenic foodstuff, rice can trigger a severe allergic reaction in babies.

29 Oct 2008

The sooner the better when it comes to HIV/AIDS treatment

New research into HIV/AIDS therapy has found that starting treatment with drugs for the AIDS virus may be better sooner than later as victims are more than 70% less likely to die when they started taking cocktails of HIV drugs earlier than currently recommended.

27 Oct 2008

Targanta Therapeutics presents preclinical data on Oritavancin against Clostridium difficile infection

Targanta Therapeutics Corporation has released the in vivo data from a preclinical study comparing the activity of its antibiotic drug candidate, oritavancin, to vancomycin in a hamster model of Clostridium difficile infection.

26 Oct 2008

Gates Foundation grant to help prevent deaths in Africa by improving antibiotic access

The Alliance for the Prudent Use of Antibiotics (APUA) has announced a $1.37 million grant from the Bill & Melinda Gates Foundation, to explore ways of reducing millions of preventable deaths from severe respiratory and diarrheal infections in Africa. This project was announced in conjunction with a colloquium at the annual ICAAC/IDSA meeting warning of increasing antibiotic resistance.

26 Oct 2008