Down Syndrome News and Research

Latest Down Syndrome News and Research

Transition completes enrolment of patients in ELND005 Phase 2 study for treatment of AD patients

Transition Therapeutics Inc. announced that its wholly owned subsidiary, Transition Therapeutics Ireland Limited completed enrolment of the Phase 2 clinical study evaluating neuropsychiatric drug candidate ELND005 as a treatment for agitation and aggression in patients with mild, moderate and severe Alzheimer's disease ("AD").

2 Mar 2015

Einstein researchers find possible clue to why older mothers have babies born with Down syndrome

Researchers at Albert Einstein College of Medicine of Yeshiva University have found a possible clue to why older mothers face a higher risk for having babies born with conditions such as Down syndrome that are characterized by abnormal chromosome numbers.

19 Feb 2015

New computer-simulated prescribing strategies for glasses may help Down syndrome patients see better

New computer-simulated prescribing strategies for glasses may improve the vision of individuals with Down syndrome, thanks to a team of University of Houston College of Optometry researchers who received a $1.67 million grant from the National Eye Institute.

12 Feb 2015

Transition Therapeutics commences underwritten public offering of common shares

Transition Therapeutics Inc. announced today that it has commenced an underwritten public offering of its common shares.

12 Feb 2015

Cell free DNA analysis less effective than sequential screening in finding fetal chromosomal abnormalities

In a study to be presented on Feb. 5 in an oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report that cell free DNA analysis is less effective than sequential screening as primary testing for fetal chromosomal abnormalities.

5 Feb 2015

Alzheimer's brains commonly have many neurons with more DNA and genomic copies of APP gene

Scientists at The Scripps Research Institute have found diverse genomic changes in single neurons from the brains of Alzheimer's patients, pointing to an unexpected factor that may underpin the most common form of the disease.

5 Feb 2015

Cell-free fetal DNA testing more effective in detecting Down syndrome

Cell-free fetal DNA testing, which measures the relative amount of free fetal DNA in a pregnant woman's blood, is a new screening test that indicates the risk of Down syndrome (trisomy 21), Edward syndrome (trisomy 18), and Patau syndrome (trisomy 13).

3 Feb 2015

Maternal age and successful egg freezing with PGS: an interview with Dr. Santiago Munné

The leading cause of of pregnancy loss or infertility is chromosomal abnormality or imbalance, where extra genetic material is present or some is missing - what’s called aneuploidy. This imbalance leads to the inability to produce viable embryos or pregnancy.

2 Dec 2014

Transition Therapeutics presents Phase 2 study of ELND005 drug for bipolar disorder

Transition Therapeutics Inc. ("Transition" or the "Company") today announced findings from a Phase 2 study of neuropsychiatric drug candidate, ELND005, as an adjunctive maintenance treatment for bipolar disorder type I patients (BPD).

4 Nov 2014

Researchers to develop new tests to evaluate cognitive growth in people with intellectual disability

Leading researchers, funded through a new, five-year, $3.2 million grant from the National Institutes of Health, are collaborating to develop and evaluate tests designed to measure and track changes in the cognitive functioning of people who typically are difficult to assess accurately: those with an intellectual disability, formerly termed mental retardation.

3 Nov 2014

High risk for congenital heart defects in Down syndrome provides tool to identify changes in genes

Down syndrome is the most common chromosomal abnormality in humans, involving a third copy of all or part of chromosome 21. In addition to intellectual disability, individuals with Down syndrome have a high risk of congenital heart defects. However, not all people with Down syndrome have them – about half have structurally normal hearts.

25 Oct 2014

Penn State scientists find that mitochondrial disease more prevalent in older moms

The discovery of a "maternal age effect" by a team of Penn State scientists that could be used to predict the accumulation of mitochondrial DNA mutations in maternal egg cells -- and the transmission of these mutations to children -- could provide valuable insights for genetic counseling.

14 Oct 2014

Women better informed about prenatal genetic testing choose fewer tests

A clinical trial led by UC San Francisco has found that when pregnant women are educated about their choices on prenatal genetic testing, the number of tests actually drops, even when the tests are offered with no out-of-pocket costs.

25 Sep 2014

Decision-support guide for prenatal genetic testing, no cost for testing result in less prenatal test use

An intervention for pregnant women that included a computerized, interactive decision-support guide regarding prenatal genetic testing, and no cost for testing, resulted in less prenatal test use and more informed choices, according to a study in the September 24 issue of JAMA.

24 Sep 2014

Study examines relationship between maternal iron intake and offspring autism risk

Mothers of children with autism are significantly less likely to report taking iron supplements before and during their pregnancies than the mothers of children who are developing normally, a study by researchers with the UC Davis MIND Institute has found.

23 Sep 2014

Research findings provide more details about earliest stages of neurodegenerative disease

The link between a protein typically associated with Alzheimer's disease and its impact on memory and cognition may not be as clear as once thought, according to a new study from the University of Wisconsin-Madison's Waisman Center.

19 Sep 2014

Treatment at earliest age reduces symptoms of autism spectrum disorder

Treatment at the earliest age when symptoms of autism spectrum disorder (ASD) appear - sometimes in infants as young as 6 months old - significantly reduces symptoms so that, by age 3, most who received the therapy had neither ASD nor developmental delay, a UC Davis MIND Institute research study has found.

9 Sep 2014

State highlights: Calif. audit finds hospital payroll wrongdoing; Ill. plans Medicaid contraception boost; Minn. union vote

Audits of a state prison and psychiatric hospital detail hundreds of thousands of dollars in improper payments and financial problems, including outright payroll fraud, and medical staff and guards receiving questionable bonuses and holiday pay, according to reports released Wednesday (St. John, 8/20).

22 Aug 2014

NTU research could lead to better treatment options for children suffering from leukaemia

A research team led by Nanyang Technological University scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia.

15 Aug 2014

Findings open up improved treatment possibilities for children suffering from leukaemia

A research team led by Nanyang Technological University (NTU) scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia.

14 Aug 2014

Down Syndrome News and Research

Latest Down Syndrome News and Research

Transition completes enrolment of patients in ELND005 Phase 2 study for treatment of AD patients

Einstein researchers find possible clue to why older mothers have babies born with Down syndrome

New computer-simulated prescribing strategies for glasses may help Down syndrome patients see better

Transition Therapeutics commences underwritten public offering of common shares

Cell free DNA analysis less effective than sequential screening in finding fetal chromosomal abnormalities

Alzheimer's brains commonly have many neurons with more DNA and genomic copies of APP gene

Cell-free fetal DNA testing more effective in detecting Down syndrome

Maternal age and successful egg freezing with PGS: an interview with Dr. Santiago Munné

Transition Therapeutics presents Phase 2 study of ELND005 drug for bipolar disorder

Researchers to develop new tests to evaluate cognitive growth in people with intellectual disability

High risk for congenital heart defects in Down syndrome provides tool to identify changes in genes

Penn State scientists find that mitochondrial disease more prevalent in older moms

Women better informed about prenatal genetic testing choose fewer tests

Decision-support guide for prenatal genetic testing, no cost for testing result in less prenatal test use

Study examines relationship between maternal iron intake and offspring autism risk

Research findings provide more details about earliest stages of neurodegenerative disease

Treatment at earliest age reduces symptoms of autism spectrum disorder

State highlights: Calif. audit finds hospital payroll wrongdoing; Ill. plans Medicaid contraception boost; Minn. union vote

NTU research could lead to better treatment options for children suffering from leukaemia

Findings open up improved treatment possibilities for children suffering from leukaemia

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Down Syndrome News and Research

Latest Down Syndrome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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