Down Syndrome News and Research

Latest Down Syndrome News and Research

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

6 May 2024

New QR4 algorithm outperforms previous models in predicting cardiovascular disease risk

A new cardiovascular risk prediction algorithm.

23 Apr 2024

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age.

16 Apr 2024

Hypoglossal nerve stimulation offers hope for pediatric Down syndrome patients with OSA

While Obstructive Sleep Apnea (OSA) affects about five percent of the general pediatric population, 80 percent of children with Down syndrome experience OSA. Continual OSA results in poor health, including disruptions to cognitive development and functioning, leading physician-researchers from Mass General Brigham to investigate better methods to treat these patients as early as possible to maximize their health outcomes.

12 Apr 2024

JAX researchers develop a powerful platform to study human health conditions

In humans, the exact same mutation in a specific gene can produce widely different outcomes. It's a bit like adding the same amount of salt to different recipes-;the effect on the finished dish can be quite different, depending on the mix of other ingredients.

3 Apr 2024

Study reveals protein structure similarities in Alzheimer's and Down syndrome

More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55-60.

29 Mar 2024

From China to Uzbekistan - United for Women’s Wellness on IWD

On the occasion of International Women's Day (IWD), BGI Genomics interview Wang Leilei, a trailblazing blind model, and Viktoriya Tsay, an Uzbek advocate of women’s health. Their stories stich a cross-cultural narrative of nurturing the nuance of women’s wellness worldwide.

From BGI Genomics 6 Mar 2024

Historic DNA analysis identifies Down and Edwards syndromes in ancient humans

By analyzing ancient DNA, an international team of researchers have uncovered cases of chromosomal disorders, including what could be the first case of Edwards syndrome ever identified from prehistoric remains.

20 Feb 2024

Speech Accessibility Project starts recruitment of U.S. and Puerto Rican stroke survivors

The Speech Accessibility Project has begun recruiting U.S. and Puerto Rican adults who have had a stroke.

2 Feb 2024

Researchers uncover a gene that causes heart defects in Down syndrome

Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21.

24 Jan 2024

Study finds reduction in mortality rate among children born with Down syndrome and heart defect

Since 1990, the mortality rate for children born with Down syndrome and a congenital heart defect has more than halved.

17 Jan 2024

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes, with new technique enhancing chromosome analysis

13 Jan 2024

Paternal sperm microRNAs also play a role in offspring health

A recent study has reported that changes in mice sperm microRNAs brought about by aging may affect the growth and development of offspring.

12 Jan 2024

Speech Accessibility Project expands to include ALS patients in U.S. and Puerto Rico

The Speech Accessibility Project has expanded its recruitment and is inviting U.S. and Puerto Rican adults living with amyotrophic lateral sclerosis to participate.

5 Jan 2024

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

Throughout the day and night, cerebrospinal fluid (CSF) pulses through small fluid-filled channels surrounding blood vessels in the brain, called perivascular spaces, to flush out neuroinflammation and other neurological waste.

2 Jan 2024

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility that light flickering at the frequency of a particular gamma-band brain rhythm could produce meaningful therapeutic effects for people with Alzheimer's disease.

20 Dec 2023

Study finds people with cognitive disabilities are less satisfied with health care

People with cognitive disabilities – like autism, attention deficit and memory loss – are less satisfied with their health care than those in the general population, according to a study published by a Rutgers researcher.

13 Dec 2023

Regular exercise can improve cognitive and physical, health of adults with Down syndrome

An exploratory study has shown that light, regular exercise can improve the cognitive, as well as physical, health of adults with Down syndrome.

29 Nov 2023

RNA-based therapy shows promise for treating leukemia in animal models

Each year, about 13,000 people in Deutschland are diagnosed with leukemia, an umbrella term that encompasses various forms of blood cancer.

27 Nov 2023

Non-invasive genetic test for fetal DNA sequencing developed

A team of investigators from Massachusetts General Hospital (MGH), Brigham and Women's Hospital (BWH), and the Broad Institute of MIT and Harvard have developed a non-invasive genetic test that can screen the blood of pregnant individuals to survey all genes for fetal DNA sequence variants.

22 Nov 2023

Down Syndrome News and Research

Latest Down Syndrome News and Research

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

New QR4 algorithm outperforms previous models in predicting cardiovascular disease risk

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Hypoglossal nerve stimulation offers hope for pediatric Down syndrome patients with OSA

JAX researchers develop a powerful platform to study human health conditions

Study reveals protein structure similarities in Alzheimer's and Down syndrome

From China to Uzbekistan - United for Women’s Wellness on IWD

Historic DNA analysis identifies Down and Edwards syndromes in ancient humans

Speech Accessibility Project starts recruitment of U.S. and Puerto Rican stroke survivors

Researchers uncover a gene that causes heart defects in Down syndrome

Study finds reduction in mortality rate among children born with Down syndrome and heart defect

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes

Paternal sperm microRNAs also play a role in offspring health

Speech Accessibility Project expands to include ALS patients in U.S. and Puerto Rico

Enlarged perivascular spaces in infancy associated with sleep problems and autism risk

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

Study finds people with cognitive disabilities are less satisfied with health care

Regular exercise can improve cognitive and physical, health of adults with Down syndrome

RNA-based therapy shows promise for treating leukemia in animal models

Non-invasive genetic test for fetal DNA sequencing developed

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Down Syndrome News and Research

Latest Down Syndrome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Newsletters you may be interested in