Endocrinology News and Research

Latest Endocrinology News and Research

Merck ditches taranabant for obesity

Merck & Co., Inc. will not seek regulatory approval for taranabant, an investigational medicine, to treat obesity and is discontinuing its Phase III clinical development program for taranabant for obesity.

2 Oct 2008

Research suggests doctors should consider kidney-sparing surgery

A study of almost 1,500 kidney cancer patients treated at Memorial Sloan Kettering Cancer Center suggests that surgery to spare as much kidney tissue as possible may improve overall survival in patients who also have reduced kidney function at the time their cancer is diagnosed. The finding is significant because both kidney cancer and decreased kidney function appear to be increasing.

2 Oct 2008

Cholesterol research, begun in the 'Little Skate,' Garners Award

New research on the way the body processes cholesterol has earned a scientist at the University of Rochester Medical Center one of the highest honors in the field.

2 Oct 2008

First genetic research model of retina receptors

A team of scientists at the University of Oklahoma Health Sciences Center has created the first genetic research model for a microscopic part of the eye that when missing causes blindness. The research appears in a recent issue of the Journal of Biological Chemistry.

30 Sep 2008

Discovery of genetic link between obesity and colon cancer risk

A new study reveals the first-ever genetic link between obesity and colon cancer risk, a finding that could lead to greater accuracy in testing for the disease, said a researcher at the University of Alabama at Birmingham (UAB).

30 Sep 2008

Existing anti-obesity drugs may be effective against flu, hepatitis and HIV

Viruses dramatically increase cellular metabolism, and existing anti-obesity drugs may represent a new way to block these metabolic changes and inhibit viral infection, according to a study published today in the journal Nature Biotechnology.

29 Sep 2008

Breast is best - the secrets of breast milk

Scientists unraveling the composition of human breast milk say it may lead to new ways to prevent and treat stomach illnesses and other diseases in babies and adults.

29 Sep 2008

New York City blacks more likely than other races to have high blood pressure, report finds

New York City blacks have the highest rate of high blood pressure of any racial or ethnic group in the city, according to a report released on Wednesday by the New York City Department of Health and Mental Hygiene, the Staten Island Advance reports.

29 Sep 2008

Discovery may help complications of diabetes - delayed gastric emptying or gastroparesis

Mayo Clinic researchers have found what may provide a solution to one of the more troubling complications of diabetes -- delayed gastric emptying or gastroparesis.

25 Sep 2008

Array BioPharma presents positive data on its glucokinase activators in type 2 diabetes

Array BioPharma Inc. has announced the presentation of preclinical data on a novel small molecule glucokinase activator (GKA), ARRY-403, a drug for the treatment of Type 2 diabetes.

25 Sep 2008

Data Safety Monitoring Board supports continuation of trial of Iluvien for diabetic macular edema

pSivida Corp. has announced that after completing its review of safety and efficacy data currently available, an independent Data Safety Monitoring Board (DSMB) has once again recommended that the two pivotal Phase III clinical trials, known collectively as the FAME (Fluocinolone Acetonide in Diabetic Macular Edema) Study continue under the current protocol, without change.

25 Sep 2008

Discovery offers new understanding of diabetes drug target

Scientists at the University of Leicester have published findings about a new advance in the study of major diabetes drug target.

25 Sep 2008

New pig model of cystic fibrosis provides better understanding of human disease

For the first time, researchers have developed a genetically altered animal model for cystic fibrosis (CF) that closely matches the characteristics of the disease in humans. By studying the complex and multi-organ disease process in the pig model, researchers can now better understand how the complications of CF develop, an advancement that may lead to new avenues for research in prevention and treatment.

25 Sep 2008

Researchers investigate impact of stress on police officers' physical and mental health

Policing is dangerous work, and the danger lurks not on the streets alone. The pressures of law enforcement put officers at risk for high blood pressure, insomnia, increased levels of destructive stress hormones, heart problems, post-traumatic stress disorder (PTSD) and suicide, University at Buffalo researchers have found through a decade of studies of police officers.

25 Sep 2008

Gene variant boosts risk of fatty liver disease

Researchers at UT Southwestern Medical Center have found that individuals who carry a specific form of the gene PNPLA3 have more fat in their livers and a greater risk of developing liver inflammation.

25 Sep 2008

Oversize waistlines are a potent risk factor for heart disease in women

A heart expert at Johns Hopkins is calling for all women with a waistline measuring more than 35 inches to get an annual check-up and detailed risk assessment for heart problems because excess abdominal fat, even in the mildly obese and overweight, leads more than a third of women to underestimate their lifetime risk of having a heart attack, stroke or chest pain (angina).

24 Sep 2008

Major study aims for new approaches to cardiovascular disease management

The Consortium for Southeastern Hypertension Control (COSEHC), headquartered at Wake Forest University Baptist Medical Center, is launching a major five-year study designed to update current guidelines for treating cardiovascular diseases, improve disease management and reduce heart attacks and strokes in the Southeast.

24 Sep 2008

What to do with leftover embryos in fertility clinics?

The majority of infertility patients are in favor of using left-over embryos for stem cell research and would also support selling left-over embryos to other couples, according to a recent survey.

24 Sep 2008

Funding dispute affects plans to develop office of minority health in Cincinnati

The Cincinnati Enquirer on Sunday examined a dispute over funding to establish a local Office of Minority Health. In March, City Manager Milton Dohoney recommended that the Cincinnati City Council approve an ordinance that would have allowed the City of Cincinnati Health Department to apply for and accept a $69,023 grant from HHS to establish the center. He said the city would supply $17,489 in matching funds.

24 Sep 2008

Exposure to bacteria might prevent type I diabetes

Researchers from Yale University and the University of Chicago have found a startling illustration of the potential for microbes to prevent disease - they found that mice exposed to common stomach bacteria were protected against the development of type I diabetes.

22 Sep 2008