Endocrinology News and Research

Latest Endocrinology News and Research

GSK begins shipments of Fluarix and FluLaval to U.S. customers for 2008-2009 flu season

GlaxoSmithKline has announced that it will begin shipment of Flulaval [Influenza Virus Vaccine] and Fluarix [Influenza Virus Vaccine] to U.S. customers for the 2008-2009 influenza season.

11 Aug 2008

Researchers identify molecular mechanism underlying a genetic brain malformation called holoprosencephaly

St. Jude Children's Research Hospital scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE).

11 Aug 2008

Scientists discover reservoir of mitochondrial DNA mutations present in the general population

Researchers at the University of Newcastle, England, and the Virginia Bioinformatics Institute at Virginia Tech in the United States have revealed a large reservoir of mitochondrial DNA mutations present in the general population. Clinical analysis of blood samples from almost 3,000 infants born in north Cumbria, England, showed that at least 1 in 200 individuals in the general public harbor mitochondrial DNA mutations that may lead to disease.

11 Aug 2008

Low vitamin D levels substantially increase risk of death

Researchers at Johns Hopkins are reporting what is believed to be the most conclusive evidence to date that inadequate levels of vitamin D, obtained from milk, fortified cereals and exposure to sunlight, lead to substantially increased risk of death.

11 Aug 2008

Bristol University receives new funds for research into stress and the brain

Over £500,000 has been awarded to Bristol University academics to fund research into how stress hormones act in the brain.

11 Aug 2008

Shocking death rate from diabetes revealed

Shocking new figures released in Britain show that diabetes accounts for more than 1 in 10 deaths in England.

11 Aug 2008

Research finds a role for the GABA neurotransmitter in maintaining energy balance

Controlling body weight is a complicated process, as any frustrated dieter might attest. But as scientists continue to investigate the brain's intricate neurocircuitry and its role in maintaining energy balance, they are forming a clearer picture of the myriad events that lead to weight gain and weight loss.

10 Aug 2008

Discovery of obesity genes

A study of 228 women has revealed genetic variants responsible for body shape. Based on work in the fruit fly Drosophila melanogaster, research published in the open access journal BMC Genetics identifies natural variation in the human LAMA5 gene as a key determinant of weight.

10 Aug 2008

New therapeutic platform technology tackles major diseases

A spin out company from basic structural biology, Asterion Ltd., has led to new technology that provides a way of creating therapeutic proteins to tackle major diseases such as cancer, diabetes and infertility.

8 Aug 2008

Genetic biomarker linked to subcutaneous growth hormone dose-response

The interindividual variability of response to subcutaneously applied protein-based drugs remains poorly understood. However, defining genetic markers that can be associated with biological effects of such drugs may improve the understanding of individual variability of response and even drug resistance.

6 Aug 2008

Recipe for cell reprogramming adds protein

A drug-like molecule called Wnt can be substituted for the cancer gene c-Myc, one of four genes added to adult cells to reprogram them to an embryonic-stem-cell-like state, according to Whitehead researchers.

6 Aug 2008

Testosterone and body fat are controlled by the same genes

Genes that control percentage of body fat are also responsible for circulating levels of testosterone in men, research published in the latest edition of Clinical Endocrinology shows. The research shows a 23% overlap between the genes that control testosterone and those that regulate body fat composition, suggesting that these two variables are partly controlled by the same set of genes.

4 Aug 2008

Vitamin C injections slow tumor growth in mice

High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences.

4 Aug 2008

FDA changes policies regarding advisory committees

The Food and Drug Administration today announced several improved policies and procedures strengthening its management of FDA advisory committees. The improvements include stricter limits on financial conflicts of interest for committee members, improved voting procedures, and improvements to the processes for disclosing information pertaining both to advisory committee members and to specific matters considered at advisory committee meetings.

4 Aug 2008

Exercise enhancing pill in the pipeline

A pill which could help people exercise for longer is in the pipeline but is sure to cause controversy as it can apparently deliver some of the benefits of exercise, even for those who do not move a muscle.

4 Aug 2008

Epilepsy drug gabapentin may reduce insomnia in recovering alcoholics

It's a Catch-22 of the highest order. People with alcohol problems often use alcohol to get to sleep -- but it actually keeps them from getting good-quality sleep all night long.

4 Aug 2008

Sleep apnea is an independent risk factor for all-cause mortality

Moderate to severe obstructive sleep apnea (OSA) is an independent risk factor for all-cause mortality, according to a study in the August 1 issue of the journal Sleep.

4 Aug 2008

Desmopressin for bed-wetting linked to convulsions in children

Australian authorities have issued a warning regarding a drug sometimes used to treat primary nocturnal enuresis (bed-wetting) in children.

3 Aug 2008

Sleep apnea associated with increased risk of death

Sleep-disordered breathing (also known as sleep apnea) is associated with an increased risk of death, according to new results from the Wisconsin Sleep Cohort, an 18-year observational study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

3 Aug 2008

New resource helps women with diabetes through healthy pregnancies

Pregnancy is a time of great excitement and anticipation. It also can be a time of anxiety, especially for women with type 1 or type 2 diabetes. Pregnancy in women who have diabetes is automatically considered high-risk. But a new, easy-to-read booklet has information to help women with diabetes experience safe, healthy pregnancies.

3 Aug 2008