Endocrinology News and Research

Latest Endocrinology News and Research

Drugs targeted at muscle cells can be of use in the treatment of diabetes patients with insulin resistance

Type 2 diabetes is a clinical disease characterised by disruption to the metabolism of glucose and lipids as well as to the production of and physiological reactions to insulin.

19 Apr 2005

Study explores parents's reaction to discovering a child has diabetes

Discovering a child has diabetes can be a traumatic and life-changing event for parents and researchers doubt whether many of them ever come to terms with it.

19 Apr 2005

Tea may be a simple, inexpensive means of preventing diabetes

Add another line to the list of benefits from drinking tea: New research in animals suggests that tea may be a simple, inexpensive means of preventing diabetes and its ensuing complications, including cataracts.

19 Apr 2005

One-meter waistline predicts high risk of diabetes and heart disease

People with a waistline of one meter or more are at serious risk of insulin resistance - an early stage in the development of diabetes and heart disease, finds a study published online by the BMJ.

19 Apr 2005

Japanese researchers reverse diabetes

Japanese researchers have successfully reversed a woman’s diabetes by transplanting insulinmaking cells (islets) from a living donor’s pancreas into her, reporting their results in a research letter published online today by The Lancet. This is the first successful operation of its kind using the islets from a living donor.

19 Apr 2005

Family history of obesity increases risk of suffering a serious heart ailment

A Johns Hopkins study finds that people who have a family history of heart disease have more reason than most to keep their weight down. In these families, the Hopkins team found that siblings who were obese or overweight had a 60 percent increased risk of suffering a serious heart ailment, such as a heart attack, before the age of 60.

19 Apr 2005

Link between insomnia and obesity

A possible link between lack of sleep (insomnia) and obesity has been traced to hypocretin/orexin cells in the hypothalamus region of the brain that are easily excited and sensitive to stress, Yale School of Medicine researchers report in the April issue of Cell Metabolism.

13 Apr 2005

History of preeclampsia increases lifetime risk for cardiovascular illness and death

In a study of mothers with a history of preeclampsia, a hypertension complication in pregnancy affecting five percent of all women, researchers at Yale have found that these women have an increased lifetime risk for cardiovascular illness and death.

13 Apr 2005

Common genetic mutation that increases the risk of inheriting Hirschsprung disease

Gene hunters at Johns Hopkins have discovered a common genetic mutation that increases the risk of inheriting a particular birth defect not by the usual route of disrupting the gene's protein-making instructions, but by altering a regulatory region of the gene. Although the condition, called Hirschsprung disease, is rare, its complex genetics mimics that of more common diseases, such as diabetes and heart disease.

13 Apr 2005

Scientists use transcription factors to increase insulin production in diabetic mice

A group of Japanese scientists has used gene therapy to deliver three insulin transcription factors, MafA, PDX-1, and NeuroD, to the livers of diabetic mice. As a result, the mice experienced an increase in insulin gene expression and insulin production, raising the possibility that this could eventually be used to treat diabetes.

13 Apr 2005

Scientists identifiy protein that seems to control the malignant features of brain tumor cells

Scientists from Wake Forest University School of Medicine have identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. The research is reported in the current issue of Molecular Cancer Research.

13 Apr 2005

Breakthough in stem cell research - three clones of cells from existing human embryonic stem cells

In an Australian first, UNSW researchers have developed three clones of cells from existing human embryonic stem cells. The breakthrough could lead to new treatments for conditions such as diabetes, Parkinson’s disease and spinal cord injury.

13 Apr 2005

Canadian cancer crisis due to aging population

According to a report by the Canadian Cancer Society, Canada's aging baby-boomers and the growing population are creating a cancer crisis, and while survival rates for many major cancers continue to improve, the Society projects that there will be 149,000 new cases of cancer diagnosed this year and 69,500 people will die of the disease, 3,500 more new cases and 1,200 deaths over last year.

12 Apr 2005

New findings about insulin-signaling in the liver could prove useful in understanding type 2 diabetes

A collaborative effort led by The Burnham Institute's Gen-Sheng Feng has created a mouse with improved glucose tolerance and insulin activity in the liver, and generated new findings about insulin-signaling in the liver that could prove useful in understanding the pathogenesis of type 2 diabetes.

12 Apr 2005

Obesity linked to diabetes

A research team headed by Professor Helena Edlund at Umeå University has achieved a breakthrough in our understanding of how obesity causes increased levels of insulin, sugar, and blood fats leading to diseases like type-2 diabetes and liver degeneration. The findings also indicate a direct way to prevent these diseases.

12 Apr 2005