Endocrinology News and Research

Latest Endocrinology News and Research

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

The use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer, accelerated their metastatic bone growth, likely because the drugs depleted the mice's intestinal flora and weakened their immune response, according to a new study by researchers at Emory University in Atlanta.

12 Sep 2022

Research could lead to a new therapeutic option for patients with bladder cancer

Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system.

12 Sep 2022

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.

9 Sep 2022

Children of women with gestational diabetes and obesity more likely to develop ADHD

Children of women with gestational diabetes and obesity may be twice as likely to develop attention-deficit/hyperactivity disorder (ADHD) compared to those whose mothers did not have obesity, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

8 Sep 2022

Low-dose ketamine is safe and effective to treat children with ADNP syndrome, study suggests

Results of a small, but unique research study, led by researchers from the Seaver Autism Center for Research and Treatment at Mount Sinai and published online in Human Genetics and Genomic Advances, suggest that low-dose ketamine is generally safe, well-tolerated and effective to treat clinical symptoms in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.

6 Sep 2022

Male hypogonadism associated with risk of hospitalization for COVID-19

Men with low testosterone levels are more likely to require hospitalization after COVID-19 infection than men with normal levels or those on testosterone therapy, according to Saint Louis University School of Medicine and Washington University School of Medicine in St. Louis researchers.

2 Sep 2022

Study shows encouraging therapeutic options for patients with relapsed multiple myeloma

Mount Sinai researchers have published results that show encouraging therapeutic options for patients with the blood cancer multiple myeloma after first-line treatment with bispecific antibodies fails.

1 Sep 2022

New risk assessment tool predicts mortality for atrial fibrillation patients after completion of TAVR

A large-scale international study led by Mount Sinai has yielded the first risk score that can help predict mortality for patients with atrial fibrillation (AFib) who have undergone a successful transcatheter aortic valve replacement (TAVR) and discharged home.

29 Aug 2022

Three-drug medication effective in preventing recurrent cardiovascular events after a heart attack

A three-drug medication known as a "polypill," developed by the Spanish National Center for Cardiovascular Research (CNIC) and Ferrer, is effective in preventing secondary adverse cardiovascular events in people who have previously had a heart attack, reducing cardiovascular mortality by 33 percent in this patient population.

26 Aug 2022

New approach using CRISPR can engineer massive quantities of cells for therapeutic applications

A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications.

25 Aug 2022

Youth-onset type 2 diabetes climbed 77% amid COVID-19, study shows

Data suggests diagnoses of type 2 diabetes in children are increasing 4-5% per year. Type 2 diabetes occurs when the cells in the body do not respond to insulin, which increases the body's need for insulin.

24 Aug 2022

Study finds a steep rise in type 2 diabetes among children during the COVID-19 pandemic

In a multi-site study of medical records, researchers at Johns Hopkins Children's Center and across the United States say they have documented a steep rise in type 2 diabetes among children during the COVID-19 pandemic.

23 Aug 2022

Research suggests a new model of how beige fat biogenesis is controlled

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

17 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Researchers collaborate on a 15-month case study to analyze patient’s recovery from impaired adrenocorticotropic hormone

Recently, 'Long COVID' is becoming a significant issue worldwide. It refers to a variety of symptoms that persist over an extended period after the patient has recovered from a novel coronavirus infection (COVID-19). In many cases, it is unclear what causes Long COVID symptoms, and there is insufficient information regarding recovery time.

10 Aug 2022

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Mount Sinai is leading a team of lung cancer researchers that has been awarded a three-year, $500,000 grant from Stand Up To Cancer to explore therapeutic approaches to lung tumors with mutations in the KRAS gene, an undertaking that could have a significant impact for a large population of cancer patients who currently lack effective treatment options.

9 Aug 2022

Poor mental health during COVID-19 pandemic associated with weight gain in people with obesity

Over the first year of the COVID-19 pandemic, almost 30% of patients with obesity gained more than 5% of their body weight, and 1 in 7 gained more than 10%.

9 Aug 2022

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai has identified a therapeutic target for the preservation and regeneration of beta cells (β cells) - cells in the pancreas that produce and distribute insulin.

4 Aug 2022

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

We are increasingly being exposed to endocrine-disrupting chemicals (EDCs) that interfere with the normal functioning of our hormones. Bisphenol A (BPA) and phthalates, which are widely used in consumer products including plastics, aluminum cans, pharmaceuticals, and cosmetics, are well-known EDCs.

4 Aug 2022

New, non-invasive imaging method may help detect an early indicator of glaucoma

A new, non-invasive ocular imaging method may be able to detect an early indicator of glaucoma in time to prevent disease progression and vision loss, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.

2 Aug 2022

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Endocrinology News and Research

Latest Endocrinology News and Research

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

Research could lead to a new therapeutic option for patients with bladder cancer

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Children of women with gestational diabetes and obesity more likely to develop ADHD

Low-dose ketamine is safe and effective to treat children with ADNP syndrome, study suggests

Male hypogonadism associated with risk of hospitalization for COVID-19

Study shows encouraging therapeutic options for patients with relapsed multiple myeloma

New risk assessment tool predicts mortality for atrial fibrillation patients after completion of TAVR

Three-drug medication effective in preventing recurrent cardiovascular events after a heart attack

New approach using CRISPR can engineer massive quantities of cells for therapeutic applications

Youth-onset type 2 diabetes climbed 77% amid COVID-19, study shows

Study finds a steep rise in type 2 diabetes among children during the COVID-19 pandemic

Research suggests a new model of how beige fat biogenesis is controlled

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

Researchers collaborate on a 15-month case study to analyze patient’s recovery from impaired adrenocorticotropic hormone

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Poor mental health during COVID-19 pandemic associated with weight gain in people with obesity

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

New, non-invasive imaging method may help detect an early indicator of glaucoma

Innovation in neuroscience drug discovery - eBook eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Endocrinology News and Research

Latest Endocrinology News and Research

Innovation in neuroscience drug discovery - eBook eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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