Estrogen News and Research

Latest Estrogen News and Research

Conventional Estrogen Receptor measurement methods may result in 10-20% false negative rate

A team of Yale Cancer Center researchers has confirmed that between 10-20% of breast cancers classified as Estrogen Receptor (ER) negative are really positive. Understanding when and why breast cancers may be misclassified has important implications for treatment and outcomes for women diagnosed with breast cancer. Its findings are published online in the June 28 Journal of Clinical Oncology.

28 Jun 2011

Researchers demonstrate how Runx3 protein could suppress breast cancer tumor growth

Researchers have identified a protein long known to regulate gene expression as a potent suppressor of breast cancer growth. Their study, in the journal Oncogene, is the first to demonstrate how this protein, known as Runx3, accomplishes this feat.

27 Jun 2011

NJIT research professor's work on sugar-based chemicals tops ACS must-read list

NJIT Research Professor Mike Jaffe's recent book chapter about sugar-based chemicals is topping the American Chemical Society (ACS) book series' must-read list.

22 Jun 2011

GTx commences Capesaris Phase IIb trial in advanced prostate cancer

GTx, Inc., announced today that it initiated a Phase IIb clinical trial evaluating Capesaris, a selective estrogen receptor alpha agonist, compared to Lupron Depot for first line treatment of advanced prostate cancer.

20 Jun 2011

Scientists create first roadmap to understand estrogen signaling in breast cancer cells

The first roadmap to mathematical modeling of a powerful basic "decision circuit" in breast cancer has been developed and published in Nature Reviews Cancer.

18 Jun 2011

Food-based soy products safe for breast cancer survivors, expert says

There has been widespread concern about whether it is safe for women with breast cancer to eat soy. An excellent source of fiber, vitamin B6 and protein, soy is usually associated with a health-conscious diet, but research concerning its safety has been mixed.

17 Jun 2011

Synta presents ganetespib Phase 1, 2 trial results against solid tumors at ASCO 2011

Synta Pharmaceuticals Corp. today presented results at the Annual Meeting of the American Society for Clinical Oncology (ASCO) from a Phase 2 single agent clinical trial of ganetespib in gastrointestinal stromal tumors (GIST) and a Phase 1 trial of ganetespib in solid tumors evaluating a twice-weekly administration schedule.

7 Jun 2011

Flaxseed of no use in menopausal hot flashes: Study

Flaxseed has been the latest agent that has been tried in treating menopausal hot flashes and it is seen that it does not reduce the incidence of the unpleasant symptoms.

7 Jun 2011

Estrogen therapy improves low bone density in teenage girls with anorexia nervosa

Estrogen therapy improves low bone density due to anorexia nervosa in teenage girls with the disease when given as a patch or as a low oral dose that is physiological.

6 Jun 2011

$Skin wrinkles may allow identification of fracture risk in early menopausal women$

Skin wrinkles may allow identification of fracture risk in early menopausal women

A news study finds that the worse a woman's skin wrinkles are during the first few years of menopause, the lower her bone density is. The results will be presented Monday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

NCIC CTG's exemestane clinical trial data on breast cancer presented at ASCO 2011

A large international Canadian-led clinical trial investigating a new way to prevent breast cancer in women at increased risk of developing the disease has found that the drug exemestane reduces this risk by 65 per cent compared with placebo.

6 Jun 2011

New study shows Bisphenol A exposure through diet has been underestimated

A new University of Missouri study shows that the exposure to the controversial chemical Bisphenol A (BPA) through diet has been underestimated by previous lab tests.

6 Jun 2011

Study suggests strong link between dying from breast cancer and being obese

Women with a healthy body weight before and after diagnosis of breast cancer are more likely to survive the disease long term, a new study finds. The results will be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

New targeted therapy may halt tumor growth in men with advanced prostate cancer

A new targeted therapy for prostate cancer halts tumor growth in animals with advanced prostate cancer that is resistant to hormone therapy, a new study finds. The results will be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

Exemestane reduces risk of breast cancer in high-risk, postmenopausal women

Today's major announcement at the American Society of Clinical Oncology annual meeting that the drug exemestane significantly reduces the risk of breast cancer in high-risk, postmenopausal women is the result of an international, randomized double-blind phase III clinical trial in which University at Buffalo researchers and hundreds of Western New York women played a critical role.

6 Jun 2011

Wrinkles and bone health: Connection

According to a new study, women who have severe skin wrinkles during the first few years of menopause also appear to have lower bone mineral density.

5 Jun 2011

Bionovo's Menerba Phase 2 trial data to be presented at Annual World Congress on Menopause

Bionovo, Inc., a pharmaceutical company focused on the discovery and development of safe and effective treatments for women's health and cancer, today announced it will be presenting data from the Phase 2 clinical trial of their lead drug candidate for postmenopausal symptoms, Menerba, to the international community at the 13th Annual World Congress on Menopause in Rome, Italy on June 11, 2011.

4 Jun 2011

Researcher to evaluate new approach for treatment of triple-negative breast cancer

A multicenter clinical trial led by a researcher at the University of Maryland Marlene and Stewart Greenebaum Cancer Center will evaluate a new approach to treat triple-negative breast cancer, an often-aggressive type of cancer that is more common among African-Americans and young women.

4 Jun 2011

Additional data supporting utility of PAM50 gene signature for breast cancer to be presented at ASCO 2011

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, today announced that researchers will present additional evidence for the potential utility of profiling breast cancer based on the PAM50 gene signature at the 2011 American Society of Clinical Oncology annual meeting taking place in Chicago, Illinois from June 3-7.

4 Jun 2011

Many women over 70 with stage I breast cancer opt for radiation therapy: ASCO

Patterns of radiation usage in breast conserving therapy for women 70 years and older with stage I breast cancer are changing: more women are opting for radioactive implants and those with estrogen positive tumors are opting out of radiation therapy, according to an abstract being presented at the American Society of Clinical Oncology annual meeting in Chicago by Thomas Jefferson University Hospital researchers on Saturday, June 4.

3 Jun 2011

Estrogen News and Research

Latest Estrogen News and Research

Conventional Estrogen Receptor measurement methods may result in 10-20% false negative rate

Researchers demonstrate how Runx3 protein could suppress breast cancer tumor growth

NJIT research professor's work on sugar-based chemicals tops ACS must-read list

GTx commences Capesaris Phase IIb trial in advanced prostate cancer

Scientists create first roadmap to understand estrogen signaling in breast cancer cells

Food-based soy products safe for breast cancer survivors, expert says

Synta presents ganetespib Phase 1, 2 trial results against solid tumors at ASCO 2011

Flaxseed of no use in menopausal hot flashes: Study

Estrogen therapy improves low bone density in teenage girls with anorexia nervosa

Skin wrinkles may allow identification of fracture risk in early menopausal women

NCIC CTG's exemestane clinical trial data on breast cancer presented at ASCO 2011

New study shows Bisphenol A exposure through diet has been underestimated

Study suggests strong link between dying from breast cancer and being obese

New targeted therapy may halt tumor growth in men with advanced prostate cancer

Exemestane reduces risk of breast cancer in high-risk, postmenopausal women

Wrinkles and bone health: Connection

Bionovo's Menerba Phase 2 trial data to be presented at Annual World Congress on Menopause

Researcher to evaluate new approach for treatment of triple-negative breast cancer

Additional data supporting utility of PAM50 gene signature for breast cancer to be presented at ASCO 2011

Many women over 70 with stage I breast cancer opt for radiation therapy: ASCO

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Estrogen News and Research

Latest Estrogen News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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