Estrogen News and Research

Latest Estrogen News and Research

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

Hormone replacement therapy for gender dysphoria may increase risk of serious cardiac events

People with gender dysphoria taking hormone replacements as part of gender affirmation therapy face a substantially increased risk of serious cardiac events, including stroke, heart attack and pulmonary embolism, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

23 Feb 2023

Effects of nanoparticles on gouty arthritis in animal models of gout

Researchers performed a systematic review and meta-analysis to explore the effects of nanoparticles on gouty arthritis using animal models.

23 Feb 2023

Men who regularly lift heavy objects at work have higher sperm counts, study suggests

A new study from researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests that men who regularly lift heavy objects at work have higher sperm counts.

22 Feb 2023

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Patients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to have more-aggressive tumors and significantly lower overall survival (OS) than those in higher-income neighborhoods, according to research led by Roswell Park Comprehensive Cancer Center.

21 Feb 2023

FDA approves first drug for ESR1-mutated breast cancer

Dr. Rajkumar Lakshmanaswamy, Ph.D., Chair of the Department of Molecular and Translational Medicine, Center of Emphasis in Cancer and Dean of the L. Frederick Francis Graduate School of Biomedical Sciences at Texas Tech University Health Sciences Center El Paso is available to speak on the Federal Drug Administration's approval of the selective estrogen receptor (ER) degrader elacestrant (Orserdu).

9 Feb 2023

UT Southwestern research could lead to new ways of controlling gene regulation

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

The Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center, was the lead site for a study evaluating Phase I and Phase III clinical trials for elacestrant, a treatment for postmenopausal women and adult men with ER+/HER2- advanced or metastatic breast cancer.

1 Feb 2023

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

Results from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free survival (PFS) times in patients with triple-negative breast cancer (TNBC) that has a "BRCA-like" phenotype.

31 Jan 2023

UK oncologists and cardiologists collaborate to prevent chemo-induced cardiomyopathy in cancer patients

Ever since she was 12 years old, Barbie Johnson has been a Kentucky girl at heart. Raised in the bluegrass, Barbie has worked at UK HealthCare for 18 years, first in gynecologic oncology and now in surgery scheduling.

26 Jan 2023

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

A multi-institutional team led by scientists from the Medical College of Wisconsin Cancer Center has discovered PD-L2 as a therapy-relevant marker to identify patients with estrogen receptor-positive breast cancer who may benefit from new immunotherapies.

26 Jan 2023

New interactive tool helps to calculate risk of developing advanced breast cancer

Breast cancer is now the leading cause of global cancer incidence among women but determining who will develop breast cancer is still a challenge for the medical community.

25 Jan 2023

Ospemifene and systemic hormone therapy improve vulvovaginal atrophy symptoms, study suggests

As women age, they are more susceptible to vaginal dryness and pain during intercourse because of vulvovaginal atrophy (VVA).

25 Jan 2023

Transcriptomic analysis of placental tissue aids in understanding the pathogenic mechanisms of SARS-CoV-2 in pregnancy at the cellular level

Researchers explored the pathogenic mechanisms of SARS-CoV-2 in pregnancy using digital spatial profiling of placental tissue.

24 Jan 2023

Transgender people in rural America struggle to find doctors willing or able to provide care

For Tammy Rainey, finding a health care provider who knows about gender-affirming care has been a challenge in the rural northern Mississippi town where she lives.

23 Jan 2023

Study identifies women with twofold increased risk of developing contralateral breast cancer

Women with cancer in one breast may be at higher risk of developing cancer in the opposite breast if they are carriers of specific genetic changes that predispose them to develop breast cancer, according to a study led by the Mayo Clinic Comprehensive Cancer Center.

20 Jan 2023

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

In this interview, News Medical spoke to Kate Lawrenson, Ph.D., about their latest research which detailed the molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

19 Jan 2023

Dementia risk in women may be reduced by hormone replacement therapy

Women are at greater risk for dementia than men, probably because of waning estrogen levels following menopause. Estrogen is a key female hormone linked to reproductive, sexual, and neurological functions. A new study published in the journal Alzheimer's Research & Therapy examines how hormone replacement works in women with a high genetic risk for AD.

17 Jan 2023

Estrogen News and Research

Latest Estrogen News and Research

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

What is the role of B cells in breast cancer pathology?

Hormone replacement therapy for gender dysphoria may increase risk of serious cardiac events

Effects of nanoparticles on gouty arthritis in animal models of gout

Men who regularly lift heavy objects at work have higher sperm counts, study suggests

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

FDA approves first drug for ESR1-mutated breast cancer

UT Southwestern research could lead to new ways of controlling gene regulation

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

UK oncologists and cardiologists collaborate to prevent chemo-induced cardiomyopathy in cancer patients

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

New interactive tool helps to calculate risk of developing advanced breast cancer

Ospemifene and systemic hormone therapy improve vulvovaginal atrophy symptoms, study suggests

Transcriptomic analysis of placental tissue aids in understanding the pathogenic mechanisms of SARS-CoV-2 in pregnancy at the cellular level

Transgender people in rural America struggle to find doctors willing or able to provide care

Study identifies women with twofold increased risk of developing contralateral breast cancer

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

Dementia risk in women may be reduced by hormone replacement therapy

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Estrogen News and Research

Latest Estrogen News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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