Estrogen News and Research

Latest Estrogen News and Research

Study links TNF to androgen deficiency in rheumatoid arthritis patients and suggest a novel pathway in inflammation

A protein involved in multiple cell functions, tumor necrosis factor (TNF) is perhaps best known for provoking destructive inflammation. Recently, drugs blocking the action of TNF have shown promise in the early treatment of rheumatoid arthritis (RA).

2 Jun 2005

Harmful chemicals may reprogram gene response to estrogen

New research shows that exposure to harmful chemicals and drugs during critical developmental periods early in life may actually "reprogram" the way certain genes respond to the female hormone estrogen. This genetic reprogramming may determine whether people with a genetic predisposition for a disease actually develop the disease.

1 Jun 2005

Organon obtains license for Merck's novel oral contraceptive

Akzo Nobel's human healthcare business, Organon, has been granted worldwide development and marketing rights by Merck KGaA affiliate Laboratoire Théramex for its novel oral contraceptive EMM 310066.

1 Jun 2005

New study linking pain relievers and breast cancer fails to convince experts

Research in recent years has consistently linked the use of aspirin and other anti-inflammatory pain relievers with a lower risk of colon cancer, but findings about the drugs' effect on breast-cancer risk have been very mixed with some studies suggesting that the pain relievers protect against breast cancer, while others have found no link.

1 Jun 2005

Environment factors can interact with genetics to increase disease risk

31 May 2005

Exposure to pharmaceutical estrogen during fetal development can permanently "reprogram" tissue in a way that determines whether tumors will develop in adulthood

Researchers at The University of Texas M. D. Anderson Cancer Center may have uncovered the reason why some people who are genetically predisposed to hormone-dependent cancers develop the disease as an adult, while others who are similarly susceptible don't.

30 May 2005

Ibuprofen use is associated with an increased risk of breast cancer

Ibuprofen use is associated with an increased risk of breast cancer, and long-term daily use of aspirin is associated with an increased risk of estrogen receptor/progesterone receptor (ER/PR)-negative breast cancer, according to a new study in the June 1 issue of the Journal of the National Cancer Institute.

30 May 2005

Chemicals in food packaging linked to breast cancer

Chemicals found in some food packaging materials have been shown in a new study to affect the development of breast tissue in mice, which suggests, say scientists, that women exposed to such chemicals, which mimic female hormones, may be at increased risk of breast cancer.

30 May 2005

A new technique might allow women diagnosed with cancer the opportunity to have children when chemotherapy and radiation treatments rob them of their fertility

Freezing eggs is one thing; thawing them safely so they can lead to pregnancy is the challenge. In the past, efforts to freeze a woman's eggs, or oocytes, have not worked well because the cells are large. When the egg is thawed, ice crystals cause damage that prevents the egg from being fertilized.

29 May 2005

Exercise boosts chances of surviving breast cancer

A new study is the first to produce evidence that exercise improves the prospects of beating a malignancy, and proves that being physically active boosts the odds that breast cancer patients will survive the disease.

25 May 2005

Obesity appears to increase the risk of prostate cancer

The obesity study examined the association between body mass index - weight to height ratio - and prostate cancer in 787 men undergoing biopsy due to an elevated tumor marker in the blood or an abnormal physical exam at a Veterans Affairs hospital in California between 1998 and 2002.

23 May 2005

High-dose Tamoxifen may prolong survival in amyotrophic lateral sclerosis (ALS)

Neurologist Benjamin Brooks, who directs the MDA ALS Center at the University of Wisconsin-Madison, presented results of a trial of tamoxifen, a drug approved for the treatment of breast cancer, at a meeting of the American Academy of Neurology in April. The trial was supported in part by MDA.

23 May 2005

Testosterone appears to benefit, not harm, cardiovascular health of middle-aged men

Although men suffer more coronary heart disease than women, the blame should not be placed on testosterone, according to a new study in the May 17, 2005, issue of the Journal of the American College of Cardiology.

18 May 2005

Pills made from the plant kudzu may help binge drinkers lose the urge

Researchers have found that drinkers seemed to lose the urge to binge-drink when they took pills made from the plant kudzu. Experts say the groundbreaking discovery may lead to a way to attack the rising binge-drinking problem which is especially prevalent among young people.

17 May 2005

Postmenopausal women who follow a low-fat diet have 24 percent less chance of a recurrence of breast cancer

The study by Rowan T. Chlebowski and colleagues at Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, involved 2,437 women aged 48 to 79 who were diagnosed with early stage breast cancer and were treated at several medical centers. All the women had the standard treatments such as surgery, radiation therapy, and chemotherapy and or tamoxifen therapy.

17 May 2005

New drug combination prevents breast cancer growth pre-surgery

A new type of drug originally developed for lung cancer can reduce the size of breast cancer tumours when taken in combination with other drugs.

17 May 2005

Gefitinib (Iressa) could reduce the size of breast cancer tumours

Giving women with early breast cancer a drug called gefitinib (Iressa) before surgery could reduce the size of their tumours, suggests a randomised trial published online today by The Lancet Oncology.

17 May 2005

Increased levels of estrogen that occur during pregnancy may be associated with improvement in psoriasis

Anecdotal reports have suggested that psoriasis tends to improve during pregnancy, according to background information in the article. The current study investigated prospectively how psoriasis fluctuates in pregnancy and correlated progesterone and estrogen levels in pregnancy with psoriatic change.

16 May 2005

Hormone Replacement Therapy (HRT) has a beneficial impact on cardiovascular health in hypertensive postmenopausal women

Oral Hormone Replacement Therapy (HRT) seems to have a beneficial impact on cardiovascular health in hypertensive postmenopausal women, researchers reported at the American Society of Hypertension Twentieth Annual Meeting held in San Francisco.

16 May 2005

Zometa reduces bone loss in patients receiving breast cancer treatment

Data presented at the American Society of Clinical Oncology (ASCO) annual meeting in Orlando, Florida, demonstrate that Zometa (zoledronic acid), an intravenous bisphosphonate, was shown to inhibit bone loss in postmenopausal women treated with Femara (letrozole) in the adjuvant breast cancer setting (directly following surgery to prevent cancer recurrence).

16 May 2005