Estrogen News and Research

Latest Estrogen News and Research

Discovery of novel mechanism by which certain breast cancers can metastasize

Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread in the major organs of the body. They hope that this would help develop new therapeutic strategies to treat the cancer.

12 Dec 2019

Anastrozole can be preventive drug-of-choice for women with high breast cancer risk

The Queen Mary University of London professor leading an international breast cancer study says anastrozole - rather than tamoxifen - should be the preventive drug-of-choice for post-menopausal women at increased risk of developing the disease.

12 Dec 2019

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

UCLA scientists have discovered one reason why autoimmune diseases are more prevalent in women than in men.

11 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone.

10 Dec 2019

Study shows safety of palbociclib for advanced breast cancer patients with unique gene alteration

Women who receive palbociclib (Ibrance) to treat their advanced breast cancer and have a gene alteration that can lead to a condition known as benign ethnic neutropenia (BEN), can safely receive the drug without major concerns of developing infections associated with neutropenia, or low white blood cell counts, say Georgetown Lombardi Comprehensive Cancer Center researchers.

9 Dec 2019

Novel nanopipette pH biosensor could help with cancer diagnosis and treatment

Nanopipettes with zwitterionic membranes may offer improved monitoring of changes in pH surrounding living cells, which can indicate traits of invasive cancer cells and their response to treatment, report researchers at Kanazawa University in Nature Communications.

6 Dec 2019

Researchers identify a missed opportunity in the treatment of ER+ breast cancers

In the United States, apart from some forms of skin cancer, breast cancer is the most common cancer in women. It is also the most common cause of death from cancer among Hispanic women and the second most common among all other women, after lung cancer.

6 Dec 2019

Researchers confirm two new prognostic markers for triple negative breast cancer

Physicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment known as AC chemotherapy, short for adjuvant doxorubicin and cyclophosphamide.

5 Dec 2019

Early cholesterol checks could save your heart

A new study published in the journal The Lancet reports that early cholesterol checking in the 20s, for instance, would help forecast the individual’s risk of ever having a stroke or heart disease over a lifetime.

5 Dec 2019

Birth control pills shrink hypothalamus

Birth control pills have been found to reduce a part of the brain that is associated with controlling the sex drive finds a new study. The study results are being presented as a preview in the annual conference of the Radiological Society of North America (RSNA).

5 Dec 2019

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

While estrogen receptor - + breast cancers express high levels of three anti-apoptotic Bcl-2 family members, pharmacological inhibition of Bcl-2 and/or Bcl-xL fails to induce cell death in ER + breast cancer cell lines, due to rapid and robust Mcl-1 upregulation.

26 Nov 2019

Women treated for early-stage breast cancer may develop invasive breast cancer

New research in the November 2019 issue of JNCCN—Journal of the National Comprehensive Cancer Network examines the implications of invasive breast cancer after breast-conserving treatment for ductal carcinoma in situ (aka DCIS, a form of non-invasive breast cancer) and which factors could impact overall survival.

25 Nov 2019

Breast-conserving treatment may be a viable alternative to mastectomy, study suggests

Approximately 10% of breast cancer patients treated with lumpectomy (breast-conserving surgery [BCS]) and whole-breast radiation (WBI) will have a subsequent in-breast local recurrence of cancer (IBTR) when followed long term.

22 Nov 2019

Low libido in older women not just down to menopause

Menopause marks the end of a woman’s reproductive years. Along with it, comes various effects, including irregular to the complete cessation of periods, insomnia, mood swings, irritability, hot flushes, and decreased sexual drive.

20 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Fresh light on why aggressive breast tumors form and how they can be treated

New research presented at the Society for Endocrinology annual conference in Brighton appears to identify novel methods of therapy for an aggressive type of breast cancer as well as uncovering potential causative factors. The focus of the study is to show how common chemicals present in our surroundings are possibly putting women at risk of a type of breast cancer called triple negative breast cancer (TNBC).

12 Nov 2019

HIV increases the prevalence of early menopause, shows study

Thanks to medical advancements, HIV-positive women now have a longer life expectancy, exposing them to numerous midlife health issues such as menopause.

6 Nov 2019

Bariatric surgery may cut genetic risk for developing breast cancer

Women with a genetic predisposition for breast cancer were 2.5 times more likely to develop a malignancy than women with the same genetic risk who underwent bariatric or weight-loss surgery, according to a new study presented today by Cleveland Clinic Florida researchers at the 36th American Society for Metabolic and Bariatric Surgery Annual Meeting at ObesityWeek 2019.

5 Nov 2019

Northwestern Medicine launches program to help women understand risk factors for osteoporosis

Loss of bone density is common as women age, particularly around menopause when women lose more bone than they make. When bone density becomes so low that fracture is likely, the condition is called osteoporosis.

23 Oct 2019

Estrogen News and Research

Latest Estrogen News and Research

Discovery of novel mechanism by which certain breast cancers can metastasize

Anastrozole can be preventive drug-of-choice for women with high breast cancer risk

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

New drug combo promises help for triple negative breast cancer patients

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Study shows safety of palbociclib for advanced breast cancer patients with unique gene alteration

Novel nanopipette pH biosensor could help with cancer diagnosis and treatment

Researchers identify a missed opportunity in the treatment of ER+ breast cancers

Researchers confirm two new prognostic markers for triple negative breast cancer

Early cholesterol checks could save your heart

Birth control pills shrink hypothalamus

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

Women treated for early-stage breast cancer may develop invasive breast cancer

Breast-conserving treatment may be a viable alternative to mastectomy, study suggests

Low libido in older women not just down to menopause

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Fresh light on why aggressive breast tumors form and how they can be treated

HIV increases the prevalence of early menopause, shows study

Bariatric surgery may cut genetic risk for developing breast cancer

Northwestern Medicine launches program to help women understand risk factors for osteoporosis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Estrogen News and Research

Latest Estrogen News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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