Fatty Liver

Fatty liver, also known as fatty liver disease (FLD), is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e. abnormal retention of lipids within a cell).

What is Fatty Liver?

Fatty liver is a very common disorder and up to 20 percent of adults and approximately 5 percent of children are affected.

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Mursla Bio's EvoLiver surpasses current standards in liver cancer surveillance, data presented at AASLD Liver Meeting 2024

Mursla Bio, a leader in Extracellular Vesicle (EV) science on a mission to significantly improve cancer outcomes for at-risk patients through the power of dynamic biopsy technology, today announced results of its multi-center clinical study, MEV01, in collaboration with leading academic institutes including University College London, Imperial College London, University Hospital of Santa Maria and the Medical University of Graz.

From Mursla Bio 25 Nov 2024

Mursla Bio announces promising results for EvoLiver test in liver cancer detection

25 Nov 2024

New research links sphingolipids to heart disease and atherosclerosis

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns.

19 Nov 2024

How alcohol impacts male health

This research explores how alcohol consumption disrupts metabolism, damages the liver, and impairs male reproductive health, emphasizing the complex mechanisms and public health implications.

18 Nov 2024

BMI's influence on disease pathogenesis uncovered in new research

The study highlights BMI's role in mediating genetic risk for diseases, suggesting a complex relationship with conditions like heart failure and osteoarthritis.

14 Nov 2024

UAB researchers reverse liver disease in mice with gene therapy

UAB researchers have reversed metabolic dysfunction-associated steatohepatitis (MASH) in mouse models. MASH is a severe liver disease associated with obesity and type 2 diabetes that affects more than 40 million people.

13 Nov 2024

New study highlights the importance of BMI in disease pathogenesis

New study from deCODE genetics/Amgen highlights the importance of BMI in pathogenesis of disease, suggesting that reducing BMI alone could lower the risk of several diseases.

12 Nov 2024

HMGB1 as a key mediator in liver disease pathogenesis

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates.

8 Nov 2024

Exploring the protective effects of HSD17B13 in hepatic steatosis

Chronic liver disease (CLD) is a growing global health challenge, accounting for millions of deaths each year. Its major contributors include metabolic dysfunction-associated steatohepatitis (MASH), alcoholic liver disease (ALD), and hepatitis C virus infection.

8 Nov 2024

Mediterranean diet may reduce type-2 diabetes risk in fatty liver patients

Researchers investigate how Mediterranean diet adherence reduces risk of type-2 diabetes in adults with metabolic dysfunction-associated fatty liver disease.

8 Nov 2024

Adipo Therapeutics shares results of studies on potential obesity treatment

Adipo Therapeutics LLC, a late-stage, preclinical biopharmaceutical company developing a potential treatment for obesity and related metabolic disorders, presented data from two studies at the annual meeting of The Obesity Society in San Antonio.

7 Nov 2024

Review: The multifaceted roles of bilirubin in liver health and disease

Bilirubin, the byproduct of hemoprotein breakdown, particularly hemoglobin, is a critical marker in diagnosing, prognosing, and managing liver diseases.

6 Nov 2024

Liver function discovery could revolutionize treatments for cardiovascular disease

A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.

18 Oct 2024

New grant aims to transform treatment for liver cancer

Currently, there are a few available treatment options for liver cancer, including a combination of immunotherapies and a class of drugs known as tyrosine kinase inhibitors (TKIs), but their long-term effects are limited.

17 Oct 2024

Semaglutide improves heart health and reduces weight in obese patients, but with side effects

Semaglutide significantly reduces cardiovascular events and adverse effects in overweight and obese patients. The study highlights semaglutide's superiority over other GLP-1 agonists for cardiovascular health.

14 Oct 2024

New research explores hydrogen sulfide as treatment for obesity

Therapies that deliver hydrogen sulfide to cells could one day become the basis of new treatments for obesity and related diseases, new research has concluded.

10 Oct 2024

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

Research explores how excessive sugar consumption can drive systemic inflammation, disrupt the gut and oral microbiomes, and contribute to periodontal inflammation, with implications for global health.

10 Oct 2024

New research offers hope for treating metabolic dysfunction-associated liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) — previously known as "non-alcoholic fatty liver disease" — affects about 25% of the global population.

9 Oct 2024

Study sheds light on a potential new strategy to prevent fatty liver

The accumulation of fats in the liver is driven by high-fat diets and obesity, and is becoming an increasingly prevalent global health concern.

7 Oct 2024

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

Researchers uncovered 1,307 genetic loci linked to metabolic syndrome, revealing brain tissue enrichment and key genetic factors in its development. The study also shows polygenic risk scores predict metabolic syndrome across populations.

1 Oct 2024