Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Novel small-molecule therapy shows promise against deadly pediatric leukemia

Mount Sinai researchers have developed a therapy that shows promise against a deadly pediatric leukemia. The small-molecule therapy was highly effective in fighting a type of acute myeloid leukemia in both in vitro and in vivo experiments, according to research published in Science Translational Medicine in September.

29 Sep 2021

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

After a gene is transcribed into RNA, modifications can occur to the subunits or "bases" that make up the RNA molecule, which can affect its structure and function. The study of these changes is known as "epitranscriptomics." These base modifications can occur to most types of RNA molecules, including microRNAs.

29 Sep 2021

Scientists turn into molecular detectives to find clues to why certain cancer therapies stop working

A new research study at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) turns cancer scientists into molecular detectives, searching for clues for why certain cancers are able to spread and evolve by studying tissues collected within hours of death.

29 Sep 2021

Primary sclerosing cholangitis: Therapy with synthetic bile acid acts directly on the immune system

Primary Sclerosing Cholangitis (PSC) is a rare, chronic inflammatory disease of the bile ducts and is difficult to treat. Studies conducted by the Division of Gastroenterology and Hepatology at MedUni Wien under the guidance of Michael Trauner (Department of Internal Medicine III) were able to show positive effects from the administration of synthetically produced bile acids and bile acid receptor agonists.

28 Sep 2021

Healthy gut microbiome needed for skeletal muscles to fully grow after exercising, study suggests

If further research can identify the substances that the bacteria of the gut are making to help muscles grow following exercise, we might be able to use some of those substances to promote the growth of muscles in people suffering from the loss of muscle as typically seen with aging or cancer.

27 Sep 2021

Diminished waveforms on EKGs of hospitalized patients can help predict worsening health, death

Specific and dynamic changes on electrocardiograms (EKGs) of hospitalized patients with COVID-19 or influenza can help predict a timeframe for worsening health and death, according to a new Mount Sinai study.

25 Sep 2021

Gram-positive and -negative bacteria found to be involved in periodontal bone loss

Mouths are filthy, harboring the second largest microbiome of the human body. Some bacteria can help break down food, among other responsibilities; other bacteria can travel into the mouth on food, fingers, pen caps and more to contribute to gum disease and other oral infections.

22 Sep 2021

Children receiving living donor liver transplant less likely to experience organ rejection

In the United States alone, 500 children will need a liver transplant this year. While liver tissue can come from living or deceased donors, no studies have demonstrated which of these methods leads to better outcomes for children. In a new publication, researchers at Children's Hospital Los Angeles pooled published results from over 8,000 pediatric patients across four continents. The data reveal that children who receive living donor liver tissue for transplants are far less likely to experience serious complications like organ rejection.

22 Sep 2021

Increased presence of certain bacteria in the gut may indicate colon cancer risk

A study published today in the journal Cell Host & Microbe reported that the increased presence of certain bacteria in a gut biome indicates a greater likelihood that colon polyps will become cancerous.

18 Sep 2021

Unique imaging technique sheds light on how cells related to IBD affect intestinal tissues

New "maps" of hundreds of thousands of cells related to inflammatory bowel disease shed greater light on their effects on intestinal tissues through a newly utilized imaging technique called "imaging mass cytometry."

16 Sep 2021

COVID-19 and the gut-lung axis

A new study explores the hypothesis that stimulation of the gut could be responsible for the lung inflammation seen in COVID-19, triggered by SARS-CoV-2.

16 Sep 2021

Genetic capacity of the gut microbiome determines weight loss success or failure

The strongest associations with weight loss success or failure – independent of BMI – are found in the genetic capacity of the gut microbiome.

15 Sep 2021

Drug accumulation alters gut bacterial metabolism and composition

In a research paper recently published in the journal Nature by Klünemann et al. (September 8th, 2021), the interaction of 15 diverse drugs with 25 common strains of gut bacteria is investigated, revealing 70 bacteria-drug interactions that include 29 entirely novel mechanisms not yet reported.

15 Sep 2021

UK Sepsis Trust calls for people to better understand the signs and symptoms of sepsis

This World Sepsis Day, the UK Sepsis Trust is calling for people to better understand the signs and symptoms of sepsis and recognize it as a medical emergency, in order to reduce the risk of death and mitigate against the very real long-term health effects of post-sepsis syndrome.

15 Sep 2021

Blocking a specific immune cell could reverse antibiotic-induced breast cancer growth

Leading scientists have identified a possible link between antibiotic use and the speed of breast cancer growth in mice, and identified a type of immune cell that could be targeted to reverse it.

15 Sep 2021

Gut microbiome can help or confer resistance to weight loss

Gut microbiota influences the ability to lose weight in humans, according to new research. The findings were published this week in mSystems, an open-access journal of the American Society for Microbiology.

14 Sep 2021

Gut microbiome profile could help predict patient's rheumatoid arthritis prognosis

A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic's Center for Individualized Medicine.

14 Sep 2021

Family's socio-economic status may influence children's composition of gut microbiome

Findings of a nationwide study led by the Translational Genomics Research Institute, an affiliate of City of Hope, suggest that a family's socio-economic status may influence children's composition of gut microbiome -; the mix of microscopic organisms within the digestive tract.

14 Sep 2021

Study compares DNA extraction and amplification methods used for microbiome research

Let's face it, we are a results-driven society. Too focused on the outcome, people don't often think about the "how." For instance, did you think about "how" you got to work this morning or did you just get there? In microbiome studies the results are the graphs and the data but the "how," like commuting, is often just part of a routine.

14 Sep 2021

Emotional support and resilience can help mitigate the psychological effects of the pandemic

Health care workers with high resilience or strong emotional support were protected against the effects of stress related to the COVID-19 pandemic compared to those who had low emotional support or resilience, according to a study published September 13 in the Journal of Medical Internet Research.

13 Sep 2021

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Novel small-molecule therapy shows promise against deadly pediatric leukemia

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

Scientists turn into molecular detectives to find clues to why certain cancer therapies stop working

Primary sclerosing cholangitis: Therapy with synthetic bile acid acts directly on the immune system

Healthy gut microbiome needed for skeletal muscles to fully grow after exercising, study suggests

Diminished waveforms on EKGs of hospitalized patients can help predict worsening health, death

Gram-positive and -negative bacteria found to be involved in periodontal bone loss

Children receiving living donor liver transplant less likely to experience organ rejection

Increased presence of certain bacteria in the gut may indicate colon cancer risk

Unique imaging technique sheds light on how cells related to IBD affect intestinal tissues

COVID-19 and the gut-lung axis

Genetic capacity of the gut microbiome determines weight loss success or failure

Drug accumulation alters gut bacterial metabolism and composition

UK Sepsis Trust calls for people to better understand the signs and symptoms of sepsis

Blocking a specific immune cell could reverse antibiotic-induced breast cancer growth

Gut microbiome can help or confer resistance to weight loss

Gut microbiome profile could help predict patient's rheumatoid arthritis prognosis

Family's socio-economic status may influence children's composition of gut microbiome

Study compares DNA extraction and amplification methods used for microbiome research

Emotional support and resilience can help mitigate the psychological effects of the pandemic

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Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Microbiology eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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