Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Rhythm, Actavis announce initiation of relamorelin Phase 2b trial for treatment of diabetic gastroparesis

Rhythm, a biopharmaceutical company, and Actavis plc, a leading global pharmaceutical company, announced today the initiation of a Phase 2b clinical trial assessing the efficacy and safety of relamorelin (RM-131), Rhythm's ghrelin agonist, for the treatment of gastroparesis in patients with type 1 and type 2 diabetes.

8 Apr 2015

Exercise benefits obese, overweight people with NAFLD

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world. A new study published in the Journal of Hepatology shows that exercise, regardless of frequency or intensity, benefits obese and overweight adults with NAFLD.

8 Apr 2015

Actavis seeks FDA marketing approval for Ambrisentan Tablets, 5 mg and 10 mg

Actavis plc today confirmed that it has filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration seeking approval to market Ambrisentan Tablets, 5 mg and 10 mg.

6 Apr 2015

NASH patients more likely to have increased intestinal permeability, shows study

Non-alcoholic steatohepatitis (NASH), the more severe form of non-alcoholic fatty liver disease (NAFLD) that can progress to liver fibrosis and cirrhosis, is associated with leakiness of the intestinal wall, which in turn may worsen liver disease, according to research published in Cellular and Molecular Gastroenterology and Hepatology, the new basic science journal of the American Gastroenterological Association.

3 Apr 2015

New study finds that walnuts have potential to benefit overall health

Multiple new research abstracts suggest walnuts may have the potential to positively affect several important health factors. From their impact on colon cancer and certain aspects of cognitive aging, to their positive effect on both gut health and vascular health, the research findings presented at Experimental Biology 2015 detail our latest understanding of walnuts' inner workings.

31 Mar 2015

Synthetic Biologics begins SYN-004 Phase 2a clinical trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced the initiation of a Phase 2a clinical trial to evaluate the gastrointestinal (GI) antibiotic-degrading effects and the safety of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent C. difficile infection (CDI).

30 Mar 2015

Fecal microbiota transplantation more successful for treating Clostridium difficile infections

Distasteful though it sounds, the transplantation of fecal matter is more successful for treating Clostridium difficile infections than previously thought.

30 Mar 2015

Women with IBD may be at increased risk for developing cervical cancer

Women with inflammatory bowel disease (IBD) may be at increased risk of cervical dysplasia and cancer, according to a new study1 published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

27 Mar 2015

Study identifies common causes of hospital readmissions following joint replacements procedures

A new study from researchers at NYU Langone's Hospital for Joint Diseases identifies common causes of hospital readmissions following total hip and knee arthoplasty procedures.

27 Mar 2015

apceth begins Agenmestencel-T Phase II clinical trial in gastrointestinal cancer patients

apceth, a global leader in engineered cell therapies, today announced the successful completion of the Phase I and initiation of the Phase II part of its ongoing monocentric Phase I/II clinical trial TREAT-ME 1 with the engineered cell therapeutic product Agenmestencel-T, at the Klinikum Grosshadern in Munich.

27 Mar 2015

Study shows high-fat diet may increase risk for depression, psychiatric disorders

Can the consumption of fatty foods change your behavior and your brain? High-fat diets have long been known to increase the risk for medical problems, including heart disease and stroke, but there is growing concern that diets high in fat might also increase the risk for depression and other psychiatric disorders.

26 Mar 2015

Researchers find strong association between lifestyles of indigenous communities and gut microbiome

An international team of researchers led by the University of Oklahoma has discovered a strong association between the lifestyles of indigenous communities and their gut microbial ecologies (gut microbiome), a study that may have implications for the health of all people.

26 Mar 2015

New AGA guideline changes clinical practice for patients with asymptomatic pancreatic cysts

A new guideline from the American Gastroenterological Association changes clinical practice by recommending longer surveillance periods for patients with asymptomatic pancreatic cysts and new criteria that limits surgery to those who will receive the most benefit.

25 Mar 2015

Norovirus vaccine may be available in the future

A multivalent candidate vaccine elicits broad antibody responses to a range of norovirus strains, including strains not included in the vaccine or previously encountered by participants, according to a new study published this week in PLOS Medicine.

25 Mar 2015

Key finding may point to immediate cause of CF exacerbations

In the genetic disorder cystic fibrosis (CF), the most severe symptoms are recurring episodes of lung inflammation and bacterial infection (known as "exacerbations") that happen from one to three times a year and cause ever-increasing amounts of lung damage through the course of a CF patient's life.

24 Mar 2015

TGAC plans to use miniaturised sequencing device to conduct live environmental surveillance

As one of the first research Institutes to take part in the MinION Access Programme (MAP) for portable DNA sequencing, introduced by Oxford Nanopore Technologies, The Genome Analysis Centre (TGAC)'s task force share their experience of the ground breaking trial so far.

From Oxford Nanopore Technologies 23 Mar 2015

Study reveals how Grhl2 plays a role in kidney function

The kidney carries out vital functions by continuously filtering the blood and excreting waste products into the urine. This is achieved by a complex system of tubules which transports the urine and regulates its composition.

19 Mar 2015

BCM-95 Curcumin improves chemotherapy's effectiveness in killing chemoresistant cancer cells

Cancer cell resistance to chemotherapy is a major cause of death in patients with colorectal cancer. In a first-of-its-kind study, BCM-95 Curcumin was found to improve chemotherapy's effectiveness in killing chemoresistant cells via a mechanism not previously identified.

19 Mar 2015

New microarray-based tool provides fast, reliable assessment of vaginal health

A new microarray-based tool, called VaginArray, offers the potential to provide a fast, reliable and low-cost assessment of vaginal health and diagnoses of infections. The research is published ahead of print March 2, in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.

19 Mar 2015

Medigus announces completion of three MUSE procedures for GERD treatment in Italy

Medigus Ltd., a medical device company developing minimally invasive endosurgical tools and a leader in direct visualization technology, announced the completion of three MUSE procedures in Italy by renowned gastroenterologist, Professor Pier Alberto Testoni, Director of Gastroenterology and Digestive Endoscopy IRCCS at San Raffaele Hospital in Milan.

18 Mar 2015

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Rhythm, Actavis announce initiation of relamorelin Phase 2b trial for treatment of diabetic gastroparesis

Exercise benefits obese, overweight people with NAFLD

Actavis seeks FDA marketing approval for Ambrisentan Tablets, 5 mg and 10 mg

NASH patients more likely to have increased intestinal permeability, shows study

New study finds that walnuts have potential to benefit overall health

Synthetic Biologics begins SYN-004 Phase 2a clinical trial to prevent C. difficile infection

Fecal microbiota transplantation more successful for treating Clostridium difficile infections

Women with IBD may be at increased risk for developing cervical cancer

Study identifies common causes of hospital readmissions following joint replacements procedures

apceth begins Agenmestencel-T Phase II clinical trial in gastrointestinal cancer patients

Study shows high-fat diet may increase risk for depression, psychiatric disorders

Researchers find strong association between lifestyles of indigenous communities and gut microbiome

New AGA guideline changes clinical practice for patients with asymptomatic pancreatic cysts

Norovirus vaccine may be available in the future

Key finding may point to immediate cause of CF exacerbations

TGAC plans to use miniaturised sequencing device to conduct live environmental surveillance

Study reveals how Grhl2 plays a role in kidney function

BCM-95 Curcumin improves chemotherapy's effectiveness in killing chemoresistant cancer cells

New microarray-based tool provides fast, reliable assessment of vaginal health

Medigus announces completion of three MUSE procedures for GERD treatment in Italy

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Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Microbiology eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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