Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Research shows how coevolution between humans and bacteria can affect gastric cancer risk

Research carried out in two distinct communities in Colombia illustrates how coevolution between humans and bacteria can affect a person's risk of disease. Working with colleagues in Columbia and the U.S., Scott Williams, PhD, a professor of genetics at the Geisel School of Medicine at Dartmouth, and his graduate student Nuri Kodaman discovered that the risk of developing gastric cancer depends heavily on both the ancestry of the person and the ancestry of Helicobacter pylori with which that person is infected.

15 Jan 2014

Study suggests effective way to counter influenza infections

McGill researchers, led by Dr. Maya Saleh of the Department of Medicine, have identified an enzyme, cIAP2 that helps the lungs protect themselves from the flu by giving them the ability to resist tissue damage. "It's a discovery that offers exciting new avenues for controlling influenza, since until now attempts to target the virus itself have proven challenging, especially in the face of emerging new strains of the virus," says Saleh, who is also a researcher at the Research Institute of the McGill University Health Centre.

15 Jan 2014

Study reveals high prevalence of TB infection among young children

A small study by investigators from the Johns Hopkins Children's Center and Byramjee Jeejeebhoy Government Medical College in India reveals high prevalence of tuberculosis infection among young children, troubling rates of disseminated disease and alarming patterns of drug resistance.

15 Jan 2014

Scientists progress towards understanding how some bacterial cells escape being killed by antibiotics

Scientists have made an important advance in understanding how a subset of bacterial cells escape being killed by many antibiotics.

10 Jan 2014

Nottingham scientists use MRI technology to assist in treatment, diagnosis of irritable bowel syndrome

Scientists at The University of Nottingham are leading the world in exploiting MRI technology to assist in the treatment and diagnosis of Irritable Bowel Syndrome (IBS), a condition that causes serious inconvenience and discomfort to sufferers.

10 Jan 2014

Nottingham scientists exploit MRI technology to assist in the treatment of IBS

Scientists at The University of Nottingham are leading the world in exploiting MRI technology to assist in the treatment and diagnosis of Irritable Bowel Syndrome, a condition that causes serious inconvenience and discomfort to sufferers.

9 Jan 2014

Subset of TH17 cells linked to inflammation in Crohn’s disease patients, find TSRI scientists

Two-thirds to three-quarters of the estimated 700,000 Americans living with Crohn’s disease, an autoimmune condition that can disrupt the entire gastrointestinal tract, will require surgery at some point during their life. Patients and physicians often turn to this surgical intervention after a patient develops resistance to current treatments, such as steroids.

9 Jan 2014

TSRI scientists identify small subset of immune cells that play major role in development of Crohn's disease

Two-thirds to three-quarters of the estimated 700,000 Americans living with Crohn's disease, an autoimmune condition that can disrupt the entire gastrointestinal tract, will require surgery at some point during their life.

9 Jan 2014

FDA approves Actavis' ANDA for Telmisartan Immediate-Release Tablets

Actavis plc today announced that it has received approval from the U.S. Food and Drug Administration on its Abbreviated New Drug Application for Telmisartan Immediate-Release Tablets, 20 mg, 40 mg and 80 mg, a generic equivalent to Boehringer Ingelheim's Micardis. Actavis intends to launch the product immediately.

9 Jan 2014

Forest Laboratories enters into definitive agreement to acquire Aptalis

Forest Laboratories, Inc. today announced that it has entered into a definitive agreement to acquire Aptalis, a privately held U.S. based specialty Gastrointestinal and Cystic Fibrosis company, for $2.9 billion in cash from its shareholders, including TPG, the global private investment firm. The acquisition, which requires review by anti-trust authorities in the US and Canada, is expected to be accretive to Forest's FY2015 non-GAAP EPS.

8 Jan 2014

Applied BioCode signs License and Supply Agreement with Genetic Analysis for BMB technology

Applied BioCode announced today that it has signed a License and Supply Agreement for its Barcoded Magnetic Bead technology with Genetic Analysis of Oslo, Norway.

7 Jan 2014

Actavis' subsidiary files ANDA for generic version of NuvaRing

Actavis plc today confirmed that its subsidiary, Warner Chilcott Company LLC, has filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market Ethinyl Estradiol and Etonogestrel Vaginal Ring, 0.015 mg/24 hour and 0.12 mg/24 hour.

26 Dec 2013

Synergy Pharmaceuticals closes patient enrollment in plecanatide phase 2b clinical trial in IBS-C

Synergy Pharmaceuticals Inc. today announced it has closed patient enrollment in its plecanatide phase 2b clinical trial in irritable bowel syndrome with constipation.

24 Dec 2013

Actavis' subsidiary receives FDA complete response letter for progestin-only patch NDA

Actavis plc today confirmed that the Company's subsidiary has received a complete response letter from the U.S. Food and Drug Administration for its New Drug Application for a progestin-only transdermal contraceptive patch (Norethindrone Transdermal Delivery System) for use by women to prevent pregnancy.

24 Dec 2013

Genotyping strategy could boost celiac screening efficacy

Genotyping for human leukocyte antigen followed by biopsy is a sensitive strategy for detecting histopathologic lesions in the close relatives of people with celiac disease, research indicates.

24 Dec 2013

Reflux disease diagnosis: an interview with Professor Peter Dettmar, Managing Director of RD Biomed Limited

Generally speaking, reflux has been a major chronic issue for probably the last 40 or 50 years. When you look at the global population, depending on which country we're talking about, around 20% to 40% of individuals have reflux disease within their populations.

23 Dec 2013

Study supports mounting evidence that inflammation may be the cause of chronic rhinosinusitis

Saint Louis University researchers have analyzed the microbiomes of people with chronic rhinosinusitis and healthy volunteers and found evidence that some chronic sinus issues may be the result of inflammation triggered by an immune response to otherwise harmless microorganisms in the sinus membranes.

20 Dec 2013

Researchers discover cancer-killing properties of frankincense in ovarian cancer

Researchers from the University of Leicester have, for the first time, demonstrated the potential of treating ovarian cancer using the Christmas gift frankincense.

20 Dec 2013

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Takeda Pharmaceutical Company Limited and Natrogen Therapeutics International, Inc. jointly announced today an agreement whereby Takeda will acquire an exclusive license to develop Natrogen's Natura-alpha compound as well as an option to acquire Natrogen. Natura-alpha is a synthetic small molecule oral compound that is believed to inhibit pro-inflammatory cytokine expression, which may help to reduce gastrointestinal inflammation. Natura-alpha is currently in Phase 2 development for the treatment of ulcerative colitis.

20 Dec 2013

Shades of gray in QoL measures after dental whitening

A complex picture has emerged of changes in oral-health-related quality of life after at-home dental bleaching, with some measures improving and others deteriorating after the treatment, a Brazilian double-blind randomized clinical trial has shown.

19 Dec 2013

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Research shows how coevolution between humans and bacteria can affect gastric cancer risk

Study suggests effective way to counter influenza infections

Study reveals high prevalence of TB infection among young children

Scientists progress towards understanding how some bacterial cells escape being killed by antibiotics

Nottingham scientists use MRI technology to assist in treatment, diagnosis of irritable bowel syndrome

Nottingham scientists exploit MRI technology to assist in the treatment of IBS

Subset of TH17 cells linked to inflammation in Crohn’s disease patients, find TSRI scientists

TSRI scientists identify small subset of immune cells that play major role in development of Crohn's disease

FDA approves Actavis' ANDA for Telmisartan Immediate-Release Tablets

Forest Laboratories enters into definitive agreement to acquire Aptalis

Applied BioCode signs License and Supply Agreement with Genetic Analysis for BMB technology

Actavis' subsidiary files ANDA for generic version of NuvaRing

Synergy Pharmaceuticals closes patient enrollment in plecanatide phase 2b clinical trial in IBS-C

Actavis' subsidiary receives FDA complete response letter for progestin-only patch NDA

Genotyping strategy could boost celiac screening efficacy

Reflux disease diagnosis: an interview with Professor Peter Dettmar, Managing Director of RD Biomed Limited

Study supports mounting evidence that inflammation may be the cause of chronic rhinosinusitis

Researchers discover cancer-killing properties of frankincense in ovarian cancer

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Shades of gray in QoL measures after dental whitening

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Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

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How can microdialysis benefit drug development

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