Gene News and Research

Latest Gene News and Research

Scientists identify biomarker strongly associated with aggressive breast cancer

Two Northwestern University scientists have identified a biomarker strongly associated with basal-like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy. The biomarker, a protein called STAT3, provides a smart target for new therapeutics designed to treat this often deadly cancer.

20 Aug 2014

Research validates Myc inhibition as effective therapeutic strategy for glioma

Research led by the Vall d'Hebron Institute of Oncology (VHIO) evidence the most conclusive preclinical results to-date validating Myc inhibition as a therapeutic strategy in glioma - a highly agressive tumor type that notoriously outsmarts current anti-cancer therapies.

19 Aug 2014

Research shows long non-coding RNAs regulate circadian clocks

Researchers at UT Southwestern Medical Center have found a new way that internal body clocks are regulated by a type of molecule known as long non-coding RNA.

19 Aug 2014

New study shows how immune system developed in the course of evolution

Scientists at the Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) in Freiburg re-activated expression of an ancient gene, which is not normally expressed in the mammalian immune system, and found that the animals developed a fish-like thymus.

19 Aug 2014

Social integration, strong family ties can help those who struggle with substance abuse

Social integration, including strong family ties, can protect one's well-being and even reduce the impact high-risk genes have on health.

19 Aug 2014

Researchers uncover role of epigenetic changes in Alzheimer's disease

A team led by researchers at the University of Exeter Medical School and King's College London has uncovered some of the strongest evidence yet that epigenetic changes in the brain play a role in Alzheimer's disease.

19 Aug 2014

BGRF scientists propose Oncofinder method for accurate analysis of gene expression data

Scientists from the Biogerontology Research Foundation (BGRF), a UK-based charity founded to support ageing research and address the challenges of a rapidly ageing population, propose a new concept for signalome-wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

19 Aug 2014

Research findings call for clinical testing of relevant drugs to prevent NASH

Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which can lead to cirrhosis and liver cancer. In recent years, NASH has become the leading cause of liver transplantation.

19 Aug 2014

Targeting club cells may help shorten duration of flu symptoms

A specialized subset of lung cells can shake flu infection, yet they remain stamped with an inflammatory gene signature that wreaks havoc in the lung, according to a study published in The Journal of Experimental Medicine.

19 Aug 2014

BRCA2 mutations herald poor prognosis in screen-detected prostate cancer

Among men with prostate cancer detected on screening, survival among those with a mutation in the BRCA2 gene is much poorer than in those without such a mutation, researchers report.

18 Aug 2014

Rare mutation in suspect gene disrupts brain circuitry in complex psychiatric disorders

Researchers have long suspected that major mental disorders are genetically-rooted diseases of synapses - the connections between neurons.

18 Aug 2014

Individual’s genetic make-up determines effect of stress on emotional centres

Our individual genetic make-up determines the effect that stress has on our emotional centres. These are the findings of a group of researchers from the MedUni Vienna. Not every individual reacts in the same way to life events that produce the same degree of stress.

18 Aug 2014

Study identifies genetic basis for Tibetan adaptation

In an environment where others struggle to survive, Tibetans thrive in the thin air on the Tibetan Plateau, with an average elevation of 14,800 feet.

18 Aug 2014

Researchers use new gene editing method to correct mutation that leads to DMD

UT Southwestern Medical Center researchers successfully used a new gene editing method to correct the mutation that leads to Duchenne muscular dystrophy (DMD) in a mouse model of the condition.

17 Aug 2014

Scientists create computer algorithm for cell and tissue engineering

In a boon to stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a "roadmap" for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.

16 Aug 2014

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Researchers from Boston University School of Medicine report that a tumor suppressor pathway, called the Hippo pathway, is responsible for sensing abnormal chromosome numbers in cells and triggering cell cycle arrest, thus preventing progression into cancer.

16 Aug 2014

Illness-linked genetic variation affects connections among neurons in the developing brain

A genetic variation linked to schizophrenia, bipolar disorder and severe depression wreaks havoc on connections among neurons in the developing brain, a team of researchers reports.

16 Aug 2014

New x-ray imaging system helps monitor effectiveness of treatment for cystic fibrosis

Scientists have developed an x-ray imaging system that enables researchers to see 'live' how effective treatments are for cystic fibrosis.

16 Aug 2014

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

15 Aug 2014

Research offers promise for personalized RNA combination therapies to treat lung cancer

Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential for new therapeutic agents to inhibit cancer cell growth. However, delivering these small RNAs to solid tumors remains a significant challenge, as the RNAs must target the correct cells and avoid being broken down by enzymes in the body.

15 Aug 2014

Gene News and Research

Latest Gene News and Research

Scientists identify biomarker strongly associated with aggressive breast cancer

Research validates Myc inhibition as effective therapeutic strategy for glioma

Research shows long non-coding RNAs regulate circadian clocks

New study shows how immune system developed in the course of evolution

Social integration, strong family ties can help those who struggle with substance abuse

Researchers uncover role of epigenetic changes in Alzheimer's disease

BGRF scientists propose Oncofinder method for accurate analysis of gene expression data

Research findings call for clinical testing of relevant drugs to prevent NASH

Targeting club cells may help shorten duration of flu symptoms

BRCA2 mutations herald poor prognosis in screen-detected prostate cancer

Rare mutation in suspect gene disrupts brain circuitry in complex psychiatric disorders

Individual’s genetic make-up determines effect of stress on emotional centres

Study identifies genetic basis for Tibetan adaptation

Researchers use new gene editing method to correct mutation that leads to DMD

Scientists create computer algorithm for cell and tissue engineering

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Illness-linked genetic variation affects connections among neurons in the developing brain

New x-ray imaging system helps monitor effectiveness of treatment for cystic fibrosis

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

Research offers promise for personalized RNA combination therapies to treat lung cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research