Gene News and Research

Latest Gene News and Research

NEBioCalculator: New online tool offers support for molecular biology experiments

NEBioCalculator, a new online "conversions and calculations" tool developed by New England Biolabs, offers bench-side support for molecular biology experimental planning.

From New England Biolabs 29 Jan 2014

Study: Genetic mutations in titin gene can cause skeletal muscle disease

A University of Arizona doctoral candidate has shown for the first time that genetic mutations in the titin gene can cause skeletal muscle myopathy, a disease in which muscle fibers do not function properly, resulting in muscle weakness.

29 Jan 2014

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

In normal development, all cells turn off genes they don’t need, often by attaching a chemical methyl group to the DNA, a process called methylation. Historically, scientists believed methyl groups could only stick to a particular DNA sequence: a cytosine followed by a guanine, called CpG. But in recent years, they have been found on other sequences, and so-called non-CpG methylation has been found in stem cells, and in neurons in the brain.

28 Jan 2014

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

If the content of many a situation comedy, not to mention late-night TV advertisements, is to be believed, there's an epidemic of balding men, and an intense desire to fix their follicular deficiencies.

28 Jan 2014

Researchers identify therapeutic target for cervix cancer

Gene related to the proliferation of cancerous cells blocked through molecular technology. A group of researchers from Mexico's General Hospital, Health Secretariat, Medicine Faculty and the Institute of Cellular Physiology of the National Autonomous University of Mexico (UNAM) identified a therapeutic target for cervix cancer: gene CDKN3.

28 Jan 2014

Researchers develop valid humanized model for facioscapulohumeral muscular dystrophy

Researchers at the Kennedy Krieger Institute recently announced study findings showing the successful development of a humanized preclinical model for facioscapulohumeral muscular dystrophy (FSHD), providing scientists with a much needed tool to accelerate novel therapeutic research and development.

28 Jan 2014

Study provides possible clue to high rate of preterm labor after human fetal surgery

As a fetal surgeon at UC San Francisco, Tippi MacKenzie, MD, has long known that conducting surgery on a fetus to correct a problems such as spina bifida often results in preterm labor and premature birth.

28 Jan 2014

Researchers discover unusually large bacteriophage that infects anthrax bacterium

From a zebra carcass on the plains of Namibia in Southern Africa, an international team of researchers has discovered a new, unusually large virus (or bacteriophage) that infects the bacterium that causes anthrax.

28 Jan 2014

BioTime: OncoCyte initiates clinical development of bladder cancer diagnostic test in U.S, China

BioTime, Inc. and its subsidiary OncoCyte Corporation today announced that OncoCyte has initiated clinical development of its bladder cancer diagnostic test in both the United States and China.

28 Jan 2014

Exposure to pesticide may increase risk of Alzheimer's disease, say researchers

Scientists have known for more than 40 years that the synthetic pesticide DDT is harmful to bird habitats and a threat to the environment.

27 Jan 2014

Jackson Laboratory associate professor receives grant to study gene regulation at RNA level

Jackson Laboratory Associate Professor Jeffrey Chuang, Ph.D., has been awarded a two-year grant totaling $519,750 from the National Human Genome Research Institute for his studies of how RNA (molecules vital to protein formation in cells) interacts with proteins to change how genes are expressed.

27 Jan 2014

South Korean lung SCC genetic secrets revealed

Close examination of DNA taken from squamous cell carcinoma of the lung in South Korean patients has identified a gene fusion that may be targeted by current treatments, scientists say.

27 Jan 2014

Research: Architecture of DNA maintained by protein ANP32E

A team of scientists from the National Cancer Centre Singapore (NCCS), the Institut de G-n-tique et de Biologie Moleculaire et Cellulaire (Strassbourg France), and the Institut Albert Bonniot (Grenoble, France) have made an important finding on how genes are regulated. This study will be released in the January 30th, 2014 print issue of the journal Nature.

27 Jan 2014

Researchers develop novel compound known to reverse spread of malignant breast cancer cells

Researchers at Cardiff University are developing a novel compound known to reverse the spread of malignant breast cancer cells.

26 Jan 2014

Large-scale analysis of over 20 tumor types increases catalog of cancer genes by 25%

A landmark study across many cancer types reveals that the universe of cancer mutations is much bigger than previously thought. By analyzing the genomes of thousands of patients' tumors, a Broad Institute-led research team has discovered many new cancer genes - expanding the list of known genes tied to these cancers by 25 percent. Moreover, the study shows that many key cancer genes still remain to be discovered.

25 Jan 2014

Scientists develop powerful RapidCaP mouse models for metastatic prostate cancer

Prostate cancer is the most common form of cancer in men. Affecting about 1 in 6 men, it is the second deadliest cancer. Research has been stymied by imperfect animal models of the disease, which are costly, take considerable time to develop, and fail to mimic the most lethal aspects of the illness.

25 Jan 2014

Novel HER2 mutation identified in familial lung adenocarcinomas

Researchers have identified a novel germline mutation in the transmembrane domain of the human epidermal growth factor receptor 2 gene in familial lung adenocarcinomas.

24 Jan 2014

Scientists identify genetic alterations in pediatric soft-tissue cancer

Scientists have mapped the genetic changes that drive tumors in rhabdomyosarcoma, a pediatric soft-tissue cancer, and found that the disease is characterized by two distinct genotypes. The genetic alterations identified in this malignancy could be useful in developing targeted diagnostic tools and treatments for children with the disease. The study, by researchers at the National Cancer Institute, part of the National Institutes of Health, and their colleagues, appeared in the Jan. 23, 2014, issue of the journal Cancer Discovery.

24 Jan 2014

Scientists aim to develop business plan to guide drug development for potential use in patients

What if an experimental treatment for an aggressive breast cancer had the potential to save women's lives, but nobody could use it because there was no money to develop and test it? With funding sources for research and development more scarce than in the past, it is not an unusual situation. It's a problem that Sourav Sinha, a Master's degree candidate at Rutgers' Graduate School of Biomedical Sciences, is working to tackle head-on.

24 Jan 2014

Researchers locate two molecules involved in perpetuating chronic pain

Setting the stage for possible advances in pain treatment, researchers at The Johns Hopkins University and the University of Maryland report they have pinpointed two molecules involved in perpetuating chronic pain in mice. The molecules, they say, also appear to have a role in the phenomenon that causes uninjured areas of the body to be more sensitive to pain when an area nearby has been hurt.

24 Jan 2014

Gene News and Research

Latest Gene News and Research

NEBioCalculator: New online tool offers support for molecular biology experiments

Study: Genetic mutations in titin gene can cause skeletal muscle disease

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

Researchers identify therapeutic target for cervix cancer

Researchers develop valid humanized model for facioscapulohumeral muscular dystrophy

Study provides possible clue to high rate of preterm labor after human fetal surgery

Researchers discover unusually large bacteriophage that infects anthrax bacterium

BioTime: OncoCyte initiates clinical development of bladder cancer diagnostic test in U.S, China

Exposure to pesticide may increase risk of Alzheimer's disease, say researchers

Jackson Laboratory associate professor receives grant to study gene regulation at RNA level

South Korean lung SCC genetic secrets revealed

Research: Architecture of DNA maintained by protein ANP32E

Researchers develop novel compound known to reverse spread of malignant breast cancer cells

Large-scale analysis of over 20 tumor types increases catalog of cancer genes by 25%

Scientists develop powerful RapidCaP mouse models for metastatic prostate cancer

Novel HER2 mutation identified in familial lung adenocarcinomas

Scientists identify genetic alterations in pediatric soft-tissue cancer

Scientists aim to develop business plan to guide drug development for potential use in patients

Researchers locate two molecules involved in perpetuating chronic pain

eBook: Using iPSCs models for human disease research and drug discovery eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research