Gene News and Research

Latest Gene News and Research

Rigontec raises €4.8 million in second closing of Series A financing round

Rigontec GmbH, a privately held biopharmaceutical company developing RNA-based immunotherapeutics for the treatment of cancer and viral diseases, today announces it has raised €4.8 million in a second closing of its Series A financing round from Forbion Capital Partners, a Dutch life-sciences venture capital firm, and Sunstone Capital, a Copenhagen based venture capital investor.

24 Mar 2015

Plexin D1 gene determines body fat distribution in humans

Scientists have known for some time that people who carry a lot of weight around their bellies are more likely to develop diabetes and heart disease than those who have bigger hips and thighs.

24 Mar 2015

Study: Progression of dysfunctional tau protein drives cognitive decline in Alzheimer's disease

By examining more than 3,600 postmortem brains, researchers at Mayo Clinic's campuses in Jacksonville, Florida, and Rochester, Minnesota, have found that the progression of dysfunctional tau protein drives the cognitive decline and memory loss seen in Alzheimer's disease.

24 Mar 2015

Scientists identify key molecules that trigger immune system to fight tularemia

Research led by scientists at St. Jude Children's Research Hospital has identified key molecules that trigger the immune system to launch an attack on the bacterium that causes tularemia.

24 Mar 2015

Vitamin D3 and metformin show promising results in preventing colorectal cancer

The concept was simple: If two compounds each individually show promise in preventing colon cancer, surely it's worth trying the two together to see if even greater impact is possible.

24 Mar 2015

Low zinc levels in older adults correspond with increased chronic inflammation

Zinc, an important mineral in human health, appears to affect how the immune system responds to stimulation, especially inflammation, new research from Oregon State University shows.

23 Mar 2015

Isis Pharmaceuticals announces positive results from ISIS-ANGPTL3Rx Phase 1 study

Isis Pharmaceuticals, Inc. announced today positive results from a Phase 1 study with ISIS-ANGPTL3Rx. In this study, healthy volunteers treated with ISIS-ANGPTL3Rx achieved dose-dependent, statistically significant reductions in angiopoietin-like 3 (ANGPTL3) of up to 93 percent with a mean reduction of up to 84 percent from baseline (p<0.001).

23 Mar 2015

GenVec collaborates with TheraBiologics to develop NSC-mediated cancer therapeutics

GenVec, Inc. today announced that it has formed a collaboration with TheraBiologics to develop cancer therapeutics leveraging both GenVec's proprietary gene delivery platform and TheraBiologics' proprietary neural stem cell (NSC) technology.

23 Mar 2015

Existing drugs could help prevent deadly familial stomach and lobular breast cancers

Deadly familial stomach and lobular breast cancers could be successfully treated at their earliest stages, or even prevented, by existing drugs that have been newly identified by cancer genetics researchers at New Zealand's University of Otago.

23 Mar 2015

Genomic Health presents 11 studies demonstrating value of Oncotype DX breast cancer test

Genomic Health today announced the presentation of 11 studies with the Oncotype DX breast cancer test at the 14th St. Gallen Breast Cancer Conference in Vienna, Austria. Studies presented include results from a real-life observational study in Ireland demonstrating significant reductions in chemotherapy and resulting cost savings when the test is used in early stage breast cancer.

23 Mar 2015

Stempeutics' Stempeucel drug receives ATMP classification from EMA for treatment of TAO

Stempeutics Research, a group company of Manipal Education and Medical Group and a Joint Venture with Cipla Group, announced today that the European Medicines Agency has granted Advanced Therapy Medicinal Product classification for its novel stem cell drug 'Stempeucel' which will be used for the treatment of Thromboangiitis Obliterans (TAO).

23 Mar 2015

Gene regulatory code remained same across the evolution

The language used in the switches that turn genes on and off has remained the same across millions of years of evolution, according to a new study led by researchers at Karolinska Institutet in Sweden. The findings, which are published in the scientific journal "eLife", indicate that the differences between animals reside in the content and length of the instructions that are written using this conserved language.

23 Mar 2015

Discovery may lead to new potential treatment for drug-resistant melanoma

In the last several years, targeted therapies - drugs that directly impact specific genes and proteins involved in the progression of cancer - have been approved for a wide variety of cancers, including melanoma, the deadliest form of skin cancer. Now, researchers at The Wistar Institute have discovered one way in which melanoma becomes resistant to a particular form of targeted therapy, and understanding this phenomenon may lead to a new melanoma target or prompt new designs of these treatments.

23 Mar 2015

Researchers find key step in understanding genetic mechanism of plants' environmental adaptability

A fundamental question pursued by plant scientists worldwide for the past decade has been answered by researchers led by the University of Sydney in Australia.

23 Mar 2015

Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) - serves as a protective barrier inhibiting the development of these diseases.

21 Mar 2015

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Amgen today announced that an application seeking marketing approval of Repatha (evolocumab) for the treatment of high cholesterol has been submitted for review to the Ministry of Health, Labour and Welfare in Japan.

21 Mar 2015

Eli Lilly, Innovent Biologics announce biotech drug development collaborations in China

Eli Lilly and Company and Innovent Biologics, Inc. today announced one of the largest biotech drug development collaborations in China to date between a multi-national and domestic company.

21 Mar 2015

Shp2 enzyme blocks protection program, boosts tumor growth

Cells have two different programs to safeguard them from getting out of control and developing cancer. One of them is senescence (biological aging). It puts cancer cells into a permanent sleep so they no longer divide and grow in an uncontrolled way.

20 Mar 2015

Cambridge scientists successfully create 'mini-lungs' to study cystic fibrosis

Scientists at the University of Cambridge have successfully created 'mini-lungs' using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease.

20 Mar 2015

New triple combination therapy shows promise in controlling advanced melanoma

Results of a new study by UCLA researchers has found that a groundbreaking new triple combination therapy shows promising signs of more effectively controlling advanced melanoma than previous BRAF + MEK inhibitor or BRAF inhibitor + immunotherapy combos alone, and with increased immune response and fewer side effects.

20 Mar 2015

Gene News and Research

Latest Gene News and Research

Rigontec raises €4.8 million in second closing of Series A financing round

Plexin D1 gene determines body fat distribution in humans

Study: Progression of dysfunctional tau protein drives cognitive decline in Alzheimer's disease

Scientists identify key molecules that trigger immune system to fight tularemia

Vitamin D3 and metformin show promising results in preventing colorectal cancer

Low zinc levels in older adults correspond with increased chronic inflammation

Isis Pharmaceuticals announces positive results from ISIS-ANGPTL3Rx Phase 1 study

GenVec collaborates with TheraBiologics to develop NSC-mediated cancer therapeutics

Existing drugs could help prevent deadly familial stomach and lobular breast cancers

Genomic Health presents 11 studies demonstrating value of Oncotype DX breast cancer test

Stempeutics' Stempeucel drug receives ATMP classification from EMA for treatment of TAO

Gene regulatory code remained same across the evolution

Discovery may lead to new potential treatment for drug-resistant melanoma

Researchers find key step in understanding genetic mechanism of plants' environmental adaptability

Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Eli Lilly, Innovent Biologics announce biotech drug development collaborations in China

Shp2 enzyme blocks protection program, boosts tumor growth

Cambridge scientists successfully create 'mini-lungs' to study cystic fibrosis

New triple combination therapy shows promise in controlling advanced melanoma

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research