Gene News and Research

Latest Gene News and Research

The Avon Foundation awards $275,000 grant to George Washington University

The Avon Foundation announced $275,000 in grants to The George Washington University (GW) School of Medicine and Health Sciences (SMHS) and GW Cancer Institute (GWCI), at the close of the 11th annual Avon Walk for Breast Cancer in Washington, D.C.

8 May 2013

Patients with ASPS appear to benefit from anti-cancer drug, cediranib

Patients with advanced alveolar soft part sarcoma (ASPS), a rare cancer, achieved some control of their disease using an experimental anti-cancer drug called cediranib.

8 May 2013

Genetic loci associated with H pylori bacteria are linked to stomach cancer

Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and stomach ulcers and is linked to stomach cancer, findings that may help explain some of the observed variation in individual risk for H pylori infection, according to a study in the May 8 issue of JAMA.

8 May 2013

Scientists reexamine gene strongly linked to Alzheimer's disease

Scientists' picture of how a gene strongly linked to Alzheimer's disease harms the brain may have to be revised, researchers at Washington University School of Medicine in St. Louis have found. People with harmful forms of the APOE gene have up to 12 times the risk of developing Alzheimer's disease compared with those who have other variations of the gene.

8 May 2013

Seven-year quest to understand how breast cancer cells resist treatment

A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death.

8 May 2013

Scientists identify TR4 protein that drives the formation of pituitary tumors in Cushing's disease

Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this potentially life-threatening disorder.

8 May 2013

Idera to present data from Phase 2 trial of IMO-3100 in patients with psoriasis at IID 2013

Idera Pharmaceuticals today announced presentation of data from its randomized, double-blind, placebo-controlled Phase 2 trial that showed improvements from baseline of up to 90% in Psoriasis Area Severity Index scores in patients with moderate to severe plaque psoriasis following four weeks of treatment with the Toll-like Receptor antagonist IMO-3100.

8 May 2013

Cell Medica treats first pediatric patient in ASPIRE Trial

Cell Medica today announced the treatment of the first patient in the ASPIRE Trial, an early stage Phase I/II clinical study investigating the safety and efficacy of Cytovir ADV for the treatment of adenovirus infections in immunosuppressed pediatric patients following bone marrow transplantation.

8 May 2013

Study shows turning up few microRNAs may offer much anti-breast-cancer activity

A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot - and without the unwanted side effects.

8 May 2013

Testing Stat5 gene amplification in prostate cancer patients could provide powerful therapy: Study

An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells contain abnormally high levels of the pro-growth protein Stat5.

8 May 2013

Research discovery may lead to effective new treatments for neurodegenerative disease

UCLA researchers led by Drs. Peiyee Lee and Richard Gatti at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have used induced pluripotent stem cells to advance disease-in-a-dish modeling of a rare genetic disorder, Ataxia Telangiectasia.

8 May 2013

New skin cancer drug successfully tested in humans

A new class of drug targeting skin cancer's genetic material has been successfully tested in humans for the first time, opening the way to new treatments for a range of conditions from skin cancers to eye diseases.

8 May 2013

Isis begins clinical study of ISIS-STAT3 in patients with metastatic liver cancer

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 1b/2a clinical study of ISIS-STAT3Rx in patients with advanced metastatic hepatocellular carcinoma (HCC).

7 May 2013

New gene implicated in Parkinson can delay onset of aging, extend life span

UCLA life scientists have identified a gene previously implicated in Parkinson's disease that can delay the onset of aging and extend the healthy life span of fruit flies. The research, they say, could have important implications for aging and disease in humans.

7 May 2013

Study offers new hope to patients suffering from laminopathies

Laminopathies are hereditary diseases that affect mainly the muscle tissue. These diseases include for example Emery-Dreifuss Muscular dystrophy, dilated cardiomyopathy, limb-girdle muscular dystrophy and Hutchison-Gilford progeria syndrome.

7 May 2013

Neuroperspective reviews status and prospects of therapeutics for Parkinson's disease

NI Research, the leading publisher of independent research on the neurotherapeutics industry, has released the May issue of NeuroPerspective, which reviews the status and prospects of therapeutics for Parkinson's.

7 May 2013

Mutations in Ggamma13 gene may contribute to certain forms of smell disorders in humans

Researchers at the Monell Center and collaborators have identified a protein that is critical to the ability of mammals to smell. Mice engineered to be lacking the Ggamma13 protein in their olfactory receptors were functionally anosmic - unable to smell.

7 May 2013

Men with severe sleep problems face increase risk of prostate cancer

Men who reported sleep problems, including difficulty falling asleep and staying asleep, had up to a twofold increased risk for prostate cancer, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

7 May 2013

Royal Society elects scientists from JIC for advances in antibiotic discovery and in crop improvement

Two scientists from the John Innes Centre have been elected as Fellows of the Royal Society, the premier scientific accolade in the UK. Their breakthroughs in fundamental research have pioneered advances in antibiotic discovery and in crop improvement from which we all benefit.

6 May 2013

Mutations in phosphatase Wip1 could be a new target for treating cancer

Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new target for the treatment of certain cancers.

6 May 2013

Gene News and Research

Latest Gene News and Research

The Avon Foundation awards $275,000 grant to George Washington University

Patients with ASPS appear to benefit from anti-cancer drug, cediranib

Genetic loci associated with H pylori bacteria are linked to stomach cancer

Scientists reexamine gene strongly linked to Alzheimer's disease

Seven-year quest to understand how breast cancer cells resist treatment

Scientists identify TR4 protein that drives the formation of pituitary tumors in Cushing's disease

Idera to present data from Phase 2 trial of IMO-3100 in patients with psoriasis at IID 2013

Cell Medica treats first pediatric patient in ASPIRE Trial

Study shows turning up few microRNAs may offer much anti-breast-cancer activity

Testing Stat5 gene amplification in prostate cancer patients could provide powerful therapy: Study

Research discovery may lead to effective new treatments for neurodegenerative disease

New skin cancer drug successfully tested in humans

Isis begins clinical study of ISIS-STAT3 in patients with metastatic liver cancer

New gene implicated in Parkinson can delay onset of aging, extend life span

Study offers new hope to patients suffering from laminopathies

Neuroperspective reviews status and prospects of therapeutics for Parkinson's disease

Mutations in Ggamma13 gene may contribute to certain forms of smell disorders in humans

Men with severe sleep problems face increase risk of prostate cancer

Royal Society elects scientists from JIC for advances in antibiotic discovery and in crop improvement

Mutations in phosphatase Wip1 could be a new target for treating cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research